Detailed information NTG1085998

Bioinformatically predicted

Overview

• Name: comE/blpR
• Type: Regulator
• Locus tag: ACJWMD_RS02320
• Genome accession: NZ_CP177182
• Coordinates: 441500..442243 (-)
• Length: 247 a.a.
• NCBI ID: WP_002886749.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain MRD6060
• Function: activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 436500..447243

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACJWMD_RS02295	-	436501..437037 (+)	537	WP_002886744.1	hypothetical protein	-
ACJWMD_RS02300	-	437130..437822 (+)	693	WP_002886745.1	hypothetical protein	-
ACJWMD_RS02305	-	438141..438800 (+)	660	WP_002886746.1	ABC transporter ATP-binding protein	-
ACJWMD_RS02310	-	438815..439531 (+)	717	WP_002886747.1	hypothetical protein	-
ACJWMD_RS02315	-	440183..441010 (-)	828	WP_224119046.1	sensor histidine kinase	-
ACJWMD_RS02320	comE/blpR	441500..442243 (-)	744	WP_002886749.1	response regulator transcription factor	Regulator
ACJWMD_RS02325	tnpA	443768..444184 (+)	417	WP_002886752.1	IS200/IS605 family transposase	-
ACJWMD_RS02330	-	444502..444888 (+)	387	WP_002886754.1	helix-turn-helix domain-containing protein	-
ACJWMD_RS02335	-	445023..445715 (+)	693	WP_002886755.1	DUF6287 domain-containing protein	-
ACJWMD_RS02340	-	445780..446070 (+)	291	WP_002885564.1	hypothetical protein	-

Sequence

Protein

• Length: 247 a.a.
• Molecular weight: 28781.30 Da
• Isoelectric Point: 7.0440

>NTDB_id=1085998 ACJWMD_RS02320 WP_002886749.1 441500..442243(-) (comE/blpR) [Streptococcus salivarius strain MRD6060]
MLNIFILEDDFLQQSRIETVIKDVISKKSLKCKGPEIYGKPSQLLDAITERGSHQLFFLDIEIKGEEKKGLDIAKEIRKK
DPNATIVFVTTHSEFMPVTFKYRVAALDFIDKALNDEFFYERVRLAIEYTMDKLGATITQDSFTFETSMAHVQVPFNNIL
FFETSPTIHKVILHTKEERMEFYASISEVERADERLYRCHRSFIVNPENILKINKEEKMAMFDNNIGCPISRTKYRGLLE
KVKSMKS

Nucleotide

• Length: 744 bp

>NTDB_id=1085998 ACJWMD_RS02320 WP_002886749.1 441500..442243(-) (comE/blpR) [Streptococcus salivarius strain MRD6060]
TTGTTAAATATTTTTATTTTAGAAGATGATTTCTTACAACAATCACGAATAGAAACAGTTATTAAGGATGTTATTTCAAA
AAAATCTCTAAAATGTAAAGGACCTGAGATTTATGGAAAACCTAGCCAATTACTTGACGCAATTACCGAAAGAGGCTCTC
ACCAACTTTTCTTTTTAGATATTGAAATCAAGGGTGAAGAAAAGAAGGGGCTAGACATTGCTAAAGAAATTCGAAAAAAA
GATCCTAATGCAACAATTGTTTTTGTAACAACACACTCAGAATTCATGCCAGTCACTTTTAAATATAGAGTTGCTGCCCT
AGATTTTATTGATAAAGCTTTGAATGATGAGTTTTTTTATGAACGTGTCCGTTTAGCAATTGAATATACTATGGATAAAC
TGGGGGCTACCATTACCCAAGATTCATTTACTTTTGAAACATCAATGGCCCACGTTCAAGTGCCTTTTAACAATATTTTA
TTTTTTGAAACGTCTCCAACAATACATAAGGTTATTTTGCATACTAAAGAAGAAAGAATGGAGTTTTACGCAAGTATTTC
AGAAGTTGAGCGTGCTGACGAACGCTTATATCGATGCCATCGTTCGTTTATCGTTAATCCTGAAAATATCCTTAAAATCA
ACAAAGAAGAAAAAATGGCAATGTTTGATAACAATATTGGATGTCCCATCTCCCGTACGAAATATAGGGGCCTTTTGGAG
AAGGTTAAATCGATGAAAAGCTAA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (4-122)

• LytTr DNA-binding domain (LytTR) (152-241)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/blpR	Streptococcus mutans UA159	54.772	97.571	0.534
comE/comE1	Streptococcus equinus JB1	44.856	98.381	0.441
comE/comE2	Streptococcus gordonii strain NCTC7865	38.057	100	0.381
comE/comE1	Streptococcus gordonii str. Challis substr. CH1	38.057	100	0.381
comE/comE2	Streptococcus equinus JB1	37.805	99.595	0.377
comE	Streptococcus pneumoniae R6	37.759	97.571	0.368
comE	Streptococcus pneumoniae TIGR4	37.759	97.571	0.368
comE	Streptococcus mitis SK321	37.759	97.571	0.368
comE	Streptococcus mitis NCTC 12261	37.759	97.571	0.368
comE	Streptococcus pneumoniae Rx1	37.759	97.571	0.368
comE	Streptococcus pneumoniae D39	37.759	97.571	0.368
comE	Streptococcus infantis strain Atu-4	36.929	97.571	0.36