Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   ACF1RT_RS01120 Genome accession   NZ_CP172847
Coordinates   229951..230982 (+) Length   343 a.a.
NCBI ID   WP_255262788.1    Uniprot ID   -
Organism   Streptococcus mutans strain DPC6143     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 224951..235982
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACF1RT_RS01110 (ACF1RT_01110) - 228561..228944 (+) 384 WP_002264248.1 DUF1033 family protein -
  ACF1RT_RS01115 (ACF1RT_01115) comYA 229074..230015 (+) 942 WP_002263435.1 competence type IV pilus ATPase ComGA Machinery gene
  ACF1RT_RS01120 (ACF1RT_01120) comYB 229951..230982 (+) 1032 WP_255262788.1 competence type IV pilus assembly protein ComGB Machinery gene
  ACF1RT_RS01125 (ACF1RT_01125) comYC 230982..231296 (+) 315 WP_002263437.1 competence type IV pilus major pilin ComGC Machinery gene
  ACF1RT_RS01130 (ACF1RT_01130) comYD 231283..231687 (+) 405 WP_002263438.1 competence type IV pilus minor pilin ComGD Machinery gene
  ACF1RT_RS01135 (ACF1RT_01135) comYE 231659..231952 (+) 294 WP_002263439.1 competence type IV pilus minor pilin ComGE Machinery gene
  ACF1RT_RS01140 (ACF1RT_01140) comYF 231939..232373 (+) 435 WP_002263440.1 competence type IV pilus minor pilin ComGF Machinery gene
  ACF1RT_RS01145 (ACF1RT_01145) comYG 232351..232740 (+) 390 WP_226711279.1 competence type IV pilus minor pilin ComGG Machinery gene
  ACF1RT_RS01150 (ACF1RT_01150) comYH 232795..233748 (+) 954 WP_002269808.1 class I SAM-dependent methyltransferase Machinery gene
  ACF1RT_RS01155 (ACF1RT_01155) - 233807..235006 (+) 1200 WP_002263443.1 acetate kinase -
  ACF1RT_RS01160 (ACF1RT_01160) tnpA 235219..235682 (+) 464 Protein_203 IS200/IS605 family transposase -

Sequence

Protein


Download         Length: 343 a.a.        Molecular weight: 39856.51 Da        Isoelectric Point: 9.5151

>NTDB_id=1069057 ACF1RT_RS01120 WP_255262788.1 229951..230982(+) (comYB) [Streptococcus mutans strain DPC6143]
MIFLQQDISLKEKHKQKKLKIKKQRKVIQLFNNLFTSGFNLTEIIDFLERSHLLAEIYTKKMRQGLLNGLHLAEIMSSLG
FSDDVVTQLALSEVHGNTQKSLLKIESYLNNLILVKKKLVEVITYPIILLIFLVVIMLGLKNYLLPQLERGNFATRLISN
FPILFLLGCCFFILLVGIFTFFSRKISRLHLIGFCSHLPFAGKYLQLYLTAYYAREWGNLIGQGVEMAQIVRLMQDQKSQ
LFREIGYDMEKALLSGQEFHQKVLDYPFFLKELSLMIEYGEVKSKLGNELEIYAEETWEHFFAKLKKATQFVQPLIFVFV
AIVIVMIYAAMLLPIYQNMEVNL

Nucleotide


Download         Length: 1032 bp        

>NTDB_id=1069057 ACF1RT_RS01120 WP_255262788.1 229951..230982(+) (comYB) [Streptococcus mutans strain DPC6143]
ATGATCTTTTTACAGCAGGATATATCACTGAAGGAGAAGCACAAGCAGAAGAAATTGAAGATTAAAAAGCAAAGAAAAGT
TATCCAGCTTTTTAATAATCTCTTTACTAGTGGTTTTAATTTAACAGAAATTATAGATTTTTTAGAACGAAGTCACTTGT
TAGCAGAAATATACACAAAGAAAATGCGACAAGGGTTGTTGAATGGTCTGCATTTGGCTGAAATAATGAGTTCTTTGGGA
TTCTCAGATGATGTTGTTACTCAATTAGCACTTTCTGAAGTTCATGGAAACACTCAAAAAAGTCTTTTAAAGATTGAATC
TTATCTAAATAATCTGATACTTGTTAAAAAGAAATTAGTTGAGGTTATCACTTATCCGATCATTTTATTGATTTTTCTTG
TCGTTATTATGTTGGGATTAAAGAATTATTTATTACCACAACTTGAAAGGGGAAATTTTGCGACTCGGTTGATTTCTAAT
TTCCCAATACTTTTCTTGCTGGGATGTTGCTTTTTTATTTTACTAGTTGGCATTTTTACTTTCTTTTCACGAAAGATCAG
TCGTCTGCATTTAATTGGTTTTTGCAGCCATTTGCCTTTTGCTGGTAAGTATTTGCAACTTTATTTAACAGCTTATTATG
CGCGTGAATGGGGTAATCTTATTGGGCAAGGAGTAGAAATGGCTCAGATAGTTAGATTGATGCAAGATCAAAAGTCACAA
CTTTTTAGAGAAATTGGCTATGATATGGAGAAGGCTCTGCTATCAGGTCAAGAGTTTCATCAAAAAGTTTTAGATTATCC
TTTCTTTTTAAAAGAACTAAGCCTTATGATTGAATATGGAGAAGTAAAGTCAAAATTGGGAAATGAATTGGAAATTTATG
CTGAGGAAACATGGGAACACTTTTTTGCAAAGTTAAAAAAAGCAACACAGTTTGTTCAGCCACTCATCTTTGTTTTTGTA
GCTATTGTTATTGTTATGATTTATGCAGCCATGCTTTTGCCAATTTATCAGAATATGGAGGTTAATTTATAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(29-146)

Type II secretion system (T2SS), protein F (T2SSF)

(214-334)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus mutans UA159

99.708

100

0.997
  comYB Streptococcus mutans UA140

99.125

100

0.991
  comYB Streptococcus gordonii str. Challis substr. CH1

60.411

99.417

0.601
  comGB/cglB Streptococcus mitis NCTC 12261

58.407

98.834

0.577
  comGB/cglB Streptococcus mitis SK321

56.548

97.959

0.554
  comGB/cglB Streptococcus pneumoniae Rx1

55.952

97.959

0.548
  comGB/cglB Streptococcus pneumoniae D39

55.952

97.959

0.548
  comGB/cglB Streptococcus pneumoniae R6

55.952

97.959

0.548
  comGB/cglB Streptococcus pneumoniae TIGR4

55.952

97.959

0.548
  comGB Lactococcus lactis subsp. cremoris KW2

51.632

98.251

0.507

Multiple sequence alignment