Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   ACFSN5_RS00815 Genome accession   NZ_CP172427
Coordinates   144362..145405 (+) Length   347 a.a.
NCBI ID   WP_277423768.1    Uniprot ID   -
Organism   Streptococcus sp. ZJ 1593     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 139362..150405
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACFSN5_RS00795 (ACFSN5_00795) - 139426..140046 (+) 621 WP_165212401.1 TetR/AcrR family transcriptional regulator -
  ACFSN5_RS00800 (ACFSN5_00800) - 140389..142764 (-) 2376 WP_165329443.1 HAD-IC family P-type ATPase -
  ACFSN5_RS00805 (ACFSN5_00805) - 142983..143357 (+) 375 WP_165329442.1 DUF1033 family protein -
  ACFSN5_RS00810 (ACFSN5_00810) comGA/cglA 143491..144438 (+) 948 WP_165212397.1 competence type IV pilus ATPase ComGA Machinery gene
  ACFSN5_RS00815 (ACFSN5_00815) comYB 144362..145405 (+) 1044 WP_277423768.1 competence type IV pilus assembly protein ComGB Machinery gene
  ACFSN5_RS00820 (ACFSN5_00820) comYC 145402..145728 (+) 327 WP_165212393.1 competence type IV pilus major pilin ComGC Machinery gene
  ACFSN5_RS00825 (ACFSN5_00825) comYD 145682..146116 (+) 435 WP_165212383.1 competence type IV pilus minor pilin ComGD Machinery gene
  ACFSN5_RS00830 (ACFSN5_00830) comYE 146088..146381 (+) 294 WP_165212381.1 competence type IV pilus minor pilin ComGE Machinery gene
  ACFSN5_RS00835 (ACFSN5_00835) comYF 146365..146802 (+) 438 WP_165212379.1 competence type IV pilus minor pilin ComGF Machinery gene
  ACFSN5_RS00840 (ACFSN5_00840) comGG 146780..147238 (+) 459 WP_165212377.1 competence type IV pilus minor pilin ComGG -
  ACFSN5_RS00845 (ACFSN5_00845) comYH 147415..148368 (+) 954 WP_165212375.1 class I SAM-dependent methyltransferase Machinery gene
  ACFSN5_RS00850 (ACFSN5_00850) - 148431..149627 (+) 1197 WP_165212373.1 acetate kinase -

Sequence

Protein


Download         Length: 347 a.a.        Molecular weight: 39965.27 Da        Isoelectric Point: 9.8874

>NTDB_id=1067648 ACFSN5_RS00815 WP_277423768.1 144362..145405(+) (comYB) [Streptococcus sp. ZJ 1593]
MRKLTSFLQQDISLTSRQKPKRLRTSRQRKVIQLFNNLLESGFTLTEIVDFLERSHLLAQYYTQEMRSSLLAGENLASMM
GRLGFSDDVVTQLALADIHGNTQGSLLKIESYLANLMTVKRKLLEVASYPIILLTFLILIMLGLRNYLLPQLEGTNLATR
IINHFPMVFLTGVLVLALVILLLTWLQRRSRKISWYSHLAKLPLLGRFAKLYLTAYYAREWGNLIGQGVEMSQIVQLMQK
QKSQLFQELGREMEDALLAGQEFHNKVLDYPFFLRELSLIIEYGQVKAKLGSELEVYAQETWDAFFSRVNRATQLIQPLV
FILVALVIVMIYAAMLLPMYHNMEVPL

Nucleotide


Download         Length: 1044 bp        

>NTDB_id=1067648 ACFSN5_RS00815 WP_277423768.1 144362..145405(+) (comYB) [Streptococcus sp. ZJ 1593]
ATAAGAAAATTGACCAGCTTTTTACAACAGGACATCTCACTTACGAGCAGGCAGAAGCCGAAAAGATTAAGAACTAGCCG
CCAGCGCAAGGTTATTCAGCTCTTTAATAATCTTTTGGAATCTGGTTTCACTCTGACTGAGATTGTGGATTTTCTGGAAC
GCAGTCATCTTCTGGCTCAGTATTATACACAGGAAATGCGTTCTAGTCTCTTAGCAGGTGAAAATCTAGCTTCTATGATG
GGGAGACTGGGCTTTTCTGATGATGTGGTGACTCAGTTGGCTTTAGCCGATATCCACGGGAATACCCAAGGCAGTCTTTT
AAAAATTGAGAGTTATCTAGCTAATTTGATGACTGTAAAAAGAAAGCTCTTGGAAGTAGCTAGTTATCCCATCATCCTTT
TAACTTTTTTAATTCTTATCATGTTGGGACTTCGCAATTACCTCTTGCCACAGTTGGAGGGAACAAACCTAGCAACCCGT
ATTATCAATCATTTTCCCATGGTTTTTCTAACAGGAGTTTTGGTCCTAGCATTGGTTATCCTTTTATTAACTTGGTTGCA
GAGGCGATCACGAAAAATTTCTTGGTACAGTCATTTGGCTAAGCTTCCCTTGCTTGGCAGATTTGCCAAACTTTACTTGA
CGGCTTATTATGCGCGGGAATGGGGGAATTTGATCGGTCAAGGGGTGGAAATGAGTCAGATTGTCCAGCTTATGCAGAAG
CAGAAGTCTCAGCTCTTTCAAGAACTTGGCCGTGAGATGGAGGATGCCTTGCTGGCCGGTCAAGAGTTTCACAATAAGGT
CTTAGATTATCCCTTCTTCCTACGAGAATTGAGTCTGATTATTGAATACGGTCAGGTCAAAGCTAAACTGGGTAGTGAGC
TAGAAGTCTATGCTCAGGAGACTTGGGACGCCTTCTTTAGCCGGGTTAACCGAGCAACCCAATTGATTCAGCCTCTGGTC
TTTATCTTGGTGGCCCTTGTTATCGTCATGATTTATGCAGCCATGCTACTGCCCATGTATCACAATATGGAGGTACCCTT
ATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(218-338)

Type II secretion system (T2SS), protein F (T2SSF)

(32-150)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus mutans UA140

65.789

98.559

0.648
  comYB Streptococcus mutans UA159

65.789

98.559

0.648
  comYB Streptococcus gordonii str. Challis substr. CH1

60.174

99.135

0.597
  comGB/cglB Streptococcus mitis NCTC 12261

57.91

96.542

0.559
  comGB/cglB Streptococcus mitis SK321

57.313

96.542

0.553
  comGB/cglB Streptococcus pneumoniae Rx1

57.015

96.542

0.55
  comGB/cglB Streptococcus pneumoniae D39

57.015

96.542

0.55
  comGB/cglB Streptococcus pneumoniae R6

57.015

96.542

0.55
  comGB/cglB Streptococcus pneumoniae TIGR4

57.015

96.542

0.55
  comGB Lactococcus lactis subsp. cremoris KW2

50.296

97.406

0.49

Multiple sequence alignment