Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYE   Type   Machinery gene
Locus tag   ACFSN5_RS00830 Genome accession   NZ_CP172427
Coordinates   146088..146381 (+) Length   97 a.a.
NCBI ID   WP_165212381.1    Uniprot ID   -
Organism   Streptococcus sp. ZJ 1593     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 141088..151381
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACFSN5_RS00805 (ACFSN5_00805) - 142983..143357 (+) 375 WP_165329442.1 DUF1033 family protein -
  ACFSN5_RS00810 (ACFSN5_00810) comGA/cglA 143491..144438 (+) 948 WP_165212397.1 competence type IV pilus ATPase ComGA Machinery gene
  ACFSN5_RS00815 (ACFSN5_00815) comYB 144362..145405 (+) 1044 WP_277423768.1 competence type IV pilus assembly protein ComGB Machinery gene
  ACFSN5_RS00820 (ACFSN5_00820) comYC 145402..145728 (+) 327 WP_165212393.1 competence type IV pilus major pilin ComGC Machinery gene
  ACFSN5_RS00825 (ACFSN5_00825) comYD 145682..146116 (+) 435 WP_165212383.1 competence type IV pilus minor pilin ComGD Machinery gene
  ACFSN5_RS00830 (ACFSN5_00830) comYE 146088..146381 (+) 294 WP_165212381.1 competence type IV pilus minor pilin ComGE Machinery gene
  ACFSN5_RS00835 (ACFSN5_00835) comYF 146365..146802 (+) 438 WP_165212379.1 competence type IV pilus minor pilin ComGF Machinery gene
  ACFSN5_RS00840 (ACFSN5_00840) comGG 146780..147238 (+) 459 WP_165212377.1 competence type IV pilus minor pilin ComGG -
  ACFSN5_RS00845 (ACFSN5_00845) comYH 147415..148368 (+) 954 WP_165212375.1 class I SAM-dependent methyltransferase Machinery gene
  ACFSN5_RS00850 (ACFSN5_00850) - 148431..149627 (+) 1197 WP_165212373.1 acetate kinase -
  ACFSN5_RS00855 (ACFSN5_00855) - 149812..150714 (+) 903 WP_165212371.1 LysR family transcriptional regulator -
  ACFSN5_RS00860 (ACFSN5_00860) - 150845..151111 (+) 267 WP_165212369.1 ACT domain-containing protein -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 10780.66 Da        Isoelectric Point: 10.3151

>NTDB_id=1067651 ACFSN5_RS00830 WP_165212381.1 146088..146381(+) (comYE) [Streptococcus sp. ZJ 1593]
MVAIKKRKIKAYILLESLIALAVLVTIVSLILGEINRNRQELAVSLHRQEALNVAQMAVQTKQDQLSLNGVTVQVQRTST
SITVYEDGKEVLHVSKN

Nucleotide


Download         Length: 294 bp        

>NTDB_id=1067651 ACFSN5_RS00830 WP_165212381.1 146088..146381(+) (comYE) [Streptococcus sp. ZJ 1593]
GTGGTCGCTATAAAAAAACGGAAAATTAAAGCTTATATTCTTTTAGAAAGTTTGATTGCTCTGGCGGTTTTGGTTACTAT
CGTTAGCCTGATTCTAGGTGAGATTAATCGGAACCGCCAAGAGTTAGCAGTCAGTCTTCATCGACAAGAAGCGCTCAATG
TCGCCCAAATGGCGGTTCAAACCAAGCAGGACCAGTTGAGTCTTAATGGGGTGACTGTCCAAGTTCAGCGAACCTCAACC
AGTATTACCGTTTATGAAGACGGAAAGGAGGTCCTTCATGTGTCCAAAAACTAG

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(13-94)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYE Streptococcus mutans UA140

51.042

98.969

0.505
  comYE Streptococcus mutans UA159

51.042

98.969

0.505
  comGE/cglE Streptococcus pneumoniae Rx1

44.681

96.907

0.433
  comGE/cglE Streptococcus pneumoniae D39

44.681

96.907

0.433
  comGE/cglE Streptococcus pneumoniae R6

44.681

96.907

0.433
  comGE/cglE Streptococcus pneumoniae TIGR4

44.681

96.907

0.433
  comGE/cglE Streptococcus mitis NCTC 12261

43.617

96.907

0.423
  comGE/cglE Streptococcus mitis SK321

43.617

96.907

0.423
  comGE Lactococcus lactis subsp. cremoris KW2

41.489

96.907

0.402

Multiple sequence alignment