Detailed information NTG1059188

Bioinformatically predicted

Overview

• Name: comE/blpR
• Type: Regulator
• Locus tag: ACFKHJ_RS00550
• Genome accession: NZ_CP170759
• Coordinates: 93733..94470 (+)
• Length: 245 a.a.
• NCBI ID: WP_239604425.1
• Uniprot ID: -
• Organism: Streptococcus parasuis strain FZ1
• Function: activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 88733..99470

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACFKHJ_RS00530	-	89315..89851 (-)	537	WP_216806237.1	GNAT family N-acetyltransferase	-
ACFKHJ_RS00535	-	89962..92166 (+)	2205	WP_239604424.1	bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase	-
ACFKHJ_RS00540	dtd	92168..92611 (+)	444	WP_130554438.1	D-aminoacyl-tRNA deacylase	-
ACFKHJ_RS00545	-	92688..92873 (+)	186	WP_024391547.1	hypothetical protein	-
ACFKHJ_RS00550	comE/blpR	93733..94470 (+)	738	WP_239604425.1	response regulator transcription factor	Regulator
ACFKHJ_RS00555	-	94467..95813 (+)	1347	WP_239604426.1	sensor histidine kinase	-
ACFKHJ_RS00560	-	95942..96067 (-)	126	WP_216806233.1	bacteriocin	-
ACFKHJ_RS00565	-	96269..97057 (+)	789	WP_239604427.1	ParA family protein	-
ACFKHJ_RS00570	-	97070..97294 (+)	225	WP_024379520.1	hypothetical protein	-
ACFKHJ_RS00575	-	97540..97683 (+)	144	WP_153594002.1	bacteriocin	-
ACFKHJ_RS00580	-	97694..97819 (+)	126	WP_105129977.1	bacteriocin	-
ACFKHJ_RS00585	-	97998..98186 (+)	189	WP_029176448.1	hypothetical protein	-
ACFKHJ_RS00590	-	98207..98398 (+)	192	WP_029176447.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
ACFKHJ_RS00595	-	98426..98635 (+)	210	WP_172089147.1	hypothetical protein	-

Sequence

Protein

• Length: 245 a.a.
• Molecular weight: 28479.40 Da
• Isoelectric Point: 5.4204

>NTDB_id=1059188 ACFKHJ_RS00550 WP_239604425.1 93733..94470(+) (comE/blpR) [Streptococcus parasuis strain FZ1]
MLNIFVLEDDFFQQSRLENAIRRCVEETSVRYKFLEVFGKPNQLLESIEEAGNHQFFFLDIEIKGEEKKGMEIAKEIRAR
DPYAVIVFVTTHSEFMPVTYRYRVSALDFIDKGLEDSDFQKAVSDVLVHAFENIDHTIAENSFVYKTETAYIQVPFSDIL
YFETSSTIHKVILKTKTGQTEFYGKVSDIAKADERLYQAHRSCVVNPLNITRLDRTNHIAYFENGESCFVSRLKQKKLAD
LLEIK

Nucleotide

• Length: 738 bp

>NTDB_id=1059188 ACFKHJ_RS00550 WP_239604425.1 93733..94470(+) (comE/blpR) [Streptococcus parasuis strain FZ1]
ATGCTTAATATTTTTGTATTAGAAGATGATTTTTTTCAGCAGAGCAGGCTAGAAAATGCTATTAGGCGGTGTGTTGAAGA
AACGTCAGTAAGGTATAAATTCCTAGAAGTTTTTGGTAAACCAAATCAGTTATTGGAATCAATTGAGGAAGCAGGCAATC
ACCAATTTTTCTTTTTAGATATTGAAATTAAAGGCGAAGAAAAGAAAGGAATGGAAATCGCTAAAGAAATCCGTGCTCGC
GATCCCTATGCTGTTATTGTCTTTGTAACAACTCACTCAGAATTTATGCCGGTAACGTATCGTTATCGAGTTTCTGCTTT
AGATTTTATAGATAAAGGCCTAGAGGATAGTGACTTTCAAAAGGCAGTATCAGATGTGTTAGTGCATGCTTTTGAAAATA
TTGATCATACTATAGCTGAAAATTCTTTTGTATATAAAACTGAAACTGCTTATATTCAAGTCCCTTTTAGTGATATTCTT
TATTTTGAAACATCATCAACGATTCATAAAGTCATTTTAAAAACGAAAACAGGTCAGACTGAGTTTTACGGGAAAGTATC
CGATATAGCGAAAGCTGACGAACGACTTTACCAGGCACATCGTTCTTGTGTAGTGAATCCATTAAATATAACAAGATTGG
ACAGAACAAACCATATTGCCTATTTTGAGAATGGAGAATCTTGTTTTGTTTCTCGTTTGAAGCAGAAGAAACTTGCAGAT
TTGCTGGAGATTAAATGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (4-123)

• LytTr DNA-binding domain (LytTR) (151-242)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/blpR	Streptococcus mutans UA159	55.649	97.551	0.543
comE/comE1	Streptococcus equinus JB1	50	97.143	0.486
comE/comE2	Streptococcus equinus JB1	41.564	99.184	0.412
comE	Streptococcus mitis NCTC 12261	38.645	100	0.396
comE	Streptococcus pneumoniae TIGR4	38.645	100	0.396
comE	Streptococcus mitis SK321	38.645	100	0.396
comE	Streptococcus infantis strain Atu-4	38.645	100	0.396
comE	Streptococcus pneumoniae Rx1	38.645	100	0.396
comE	Streptococcus pneumoniae D39	38.645	100	0.396
comE	Streptococcus pneumoniae R6	38.645	100	0.396
comE/comE1	Streptococcus gordonii str. Challis substr. CH1	38.71	100	0.392
comE/comE2	Streptococcus gordonii strain NCTC7865	38.71	100	0.392