Detailed information    

insolico Bioinformatically predicted

Overview


Name   comGC   Type   Machinery gene
Locus tag   ACFDA9_RS06180 Genome accession   NZ_CP170245
Coordinates   1280883..1281200 (+) Length   105 a.a.
NCBI ID   WP_381405476.1    Uniprot ID   -
Organism   Staphylococcus epidermidis strain Q17     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 1275883..1286200
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACFDA9_RS06150 (ACFDA9_06145) - 1276660..1276860 (+) 201 WP_002446537.1 YqgQ family protein -
  ACFDA9_RS06155 (ACFDA9_06150) - 1276860..1277846 (+) 987 WP_002446536.1 ROK family glucokinase -
  ACFDA9_RS06160 (ACFDA9_06155) - 1277846..1278172 (+) 327 WP_070853595.1 MTH1187 family thiamine-binding protein -
  ACFDA9_RS06165 (ACFDA9_06160) - 1278172..1278795 (+) 624 WP_002446535.1 MBL fold metallo-hydrolase -
  ACFDA9_RS06170 (ACFDA9_06165) comGA 1278852..1279826 (+) 975 WP_145377817.1 competence type IV pilus ATPase ComGA Machinery gene
  ACFDA9_RS06175 (ACFDA9_06170) comGB 1279798..1280865 (+) 1068 WP_002446533.1 competence type IV pilus assembly protein ComGB Machinery gene
  ACFDA9_RS06180 (ACFDA9_06175) comGC 1280883..1281200 (+) 318 WP_381405476.1 competence type IV pilus major pilin ComGC Machinery gene
  ACFDA9_RS06185 (ACFDA9_06180) comGD 1281190..1281627 (+) 438 WP_002446531.1 competence type IV pilus minor pilin ComGD -
  ACFDA9_RS06190 (ACFDA9_06185) - 1281614..1281907 (+) 294 WP_002446530.1 hypothetical protein -
  ACFDA9_RS06195 (ACFDA9_06190) - 1281831..1282322 (+) 492 WP_070853594.1 competence type IV pilus minor pilin ComGF -
  ACFDA9_RS06200 (ACFDA9_06195) - 1282487..1282999 (+) 513 WP_002457723.1 shikimate kinase -
  ACFDA9_RS06205 (ACFDA9_06200) gcvT 1283217..1284308 (+) 1092 WP_002457722.1 glycine cleavage system aminomethyltransferase GcvT -
  ACFDA9_RS06210 (ACFDA9_06205) gcvPA 1284328..1285674 (+) 1347 WP_002446526.1 aminomethyl-transferring glycine dehydrogenase subunit GcvPA -

Sequence


Protein


Download         Length: 105 a.a.        Molecular weight: 11492.52 Da        Isoelectric Point: 8.5267

>NTDB_id=1055874 ACFDA9_RS06180 WP_381405476.1 1280883..1281200(+) (comGC) [Staphylococcus epidermidis strain Q17]
MKTLKLLKQTRAFTLIEMLLVLLIISLLLILIIPNIAKQTSHIQSTGCDAQVKMVNSQIEAYALKHNRDPSNIDDLVSDG
FIKEGQKTCKSGQTISIANGEAVAN

Nucleotide


Download         Length: 318 bp        

>NTDB_id=1055874 ACFDA9_RS06180 WP_381405476.1 1280883..1281200(+) (comGC) [Staphylococcus epidermidis strain Q17]
ATGAAAACATTGAAATTATTGAAACAAACACGAGCATTTACCTTGATAGAAATGCTTTTAGTATTACTAATAATCAGTTT
ATTATTAATACTTATAATTCCAAATATTGCAAAACAAACATCTCATATTCAGTCAACTGGATGTGATGCTCAAGTTAAAA
TGGTAAACAGTCAAATAGAAGCCTACGCTTTAAAACATAACCGCGACCCTTCTAATATTGATGATTTGGTTTCAGATGGT
TTTATAAAAGAAGGACAAAAAACATGTAAATCCGGTCAGACAATTAGTATTGCAAATGGAGAGGCAGTTGCCAATTAA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC Staphylococcus aureus N315

85.294

97.143

0.829

  comGC Staphylococcus aureus MW2

85.294

97.143

0.829

  comGC/cglC Streptococcus mitis SK321

44.66

98.095

0.438

  comGC/cglC Streptococcus pneumoniae R6

44.681

89.524

0.4

  comGC/cglC Streptococcus pneumoniae TIGR4

44.681

89.524

0.4

  comGC/cglC Streptococcus pneumoniae Rx1

44.681

89.524

0.4

  comGC/cglC Streptococcus pneumoniae D39

44.681

89.524

0.4

  comYC Streptococcus mutans UA159

48.837

81.905

0.4

  comYC Streptococcus mutans UA140

48.837

81.905

0.4

  comYC Streptococcus suis isolate S10

47.674

81.905

0.39

  comYC Streptococcus gordonii str. Challis substr. CH1

47.674

81.905

0.39

  comGC/cglC Streptococcus mitis NCTC 12261

51.316

72.381

0.371

  comGC Lactococcus lactis subsp. cremoris KW2

47.561

78.095

0.371

  comGC Bacillus subtilis subsp. subtilis str. 168

41.758

86.667

0.362


Multiple sequence alignment