Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   BCV18_RS10445 Genome accession   NZ_CP170009
Coordinates   2248018..2249247 (-) Length   409 a.a.
NCBI ID   WP_016768204.1    Uniprot ID   A0A7Z1S1U0
Organism   Vibrio cyclitrophicus strain 10N.286.54.F2     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2243018..2254247
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BCV18_RS10405 (BCV18_10405) rpsP 2243119..2243367 (+) 249 WP_004410028.1 30S ribosomal protein S16 -
  BCV18_RS10410 (BCV18_10410) rimM 2243392..2243946 (+) 555 WP_016768202.1 ribosome maturation factor RimM -
  BCV18_RS10415 (BCV18_10415) trmD 2243973..2244713 (+) 741 WP_010435912.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  BCV18_RS10420 (BCV18_10420) rplS 2244773..2245126 (+) 354 WP_004735514.1 50S ribosomal protein L19 -
  BCV18_RS10425 (BCV18_10425) yacG 2245419..2245616 (-) 198 WP_010435916.1 DNA gyrase inhibitor YacG -
  BCV18_RS10430 (BCV18_10430) zapD 2245698..2246438 (-) 741 WP_010435917.1 cell division protein ZapD -
  BCV18_RS10435 (BCV18_10435) coaE 2246465..2247079 (-) 615 WP_010435920.1 dephospho-CoA kinase -
  BCV18_RS10440 (BCV18_10440) pilD 2247082..2247951 (-) 870 WP_016768203.1 prepilin peptidase Machinery gene
  BCV18_RS10445 (BCV18_10445) pilC 2248018..2249247 (-) 1230 WP_016768204.1 type II secretion system F family protein Machinery gene
  BCV18_RS10450 (BCV18_10450) pilB 2249262..2250947 (-) 1686 WP_065100288.1 type IV-A pilus assembly ATPase PilB Machinery gene
  BCV18_RS10455 (BCV18_10455) pilA 2250947..2251420 (-) 474 WP_016790756.1 pilin Machinery gene
  BCV18_RS10460 (BCV18_10460) nadC 2251674..2252564 (-) 891 WP_004738163.1 carboxylating nicotinate-nucleotide diphosphorylase -
  BCV18_RS10465 (BCV18_10465) ampD 2252648..2253247 (+) 600 WP_016790757.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -

Sequence

Protein


Download         Length: 409 a.a.        Molecular weight: 45165.12 Da        Isoelectric Point: 10.1000

>NTDB_id=1054433 BCV18_RS10445 WP_016768204.1 2248018..2249247(-) (pilC) [Vibrio cyclitrophicus strain 10N.286.54.F2]
MSSKSKQSQLKNYHWKGINSSGKKMSGQSLALTELEVREKLKEQHIQIKKIKKKSISAITRLTHRVKAKDITILTRQLAT
MLATGVPIVQAIKLVSDNHRKAEMKSILSHICKGVEAGTPISKAMRTASRHFDDLYTDLVATGELSGNLAQVFERLATYR
EKSEQLKAKVVKALIYPAMVVTVALTVSYLMLTMVIPEFESMFSGFGADLPWFTQQVLDLSHWMQAYSFYTALGIGATSL
VVHQLCQRSYSIRLSASRLVLRFPVLGGVMAKASIAKFSRTLSTSFSSGIPILMSLKTTAKTAGSLHYESAIIEVHRETA
AGMPMYIAMRNTNAFPEMVLQMVMIGEESGNLDDMLNKVASIYEFEVDNTVDNLGKILEPLIIVFLGTVVGGLVVAMYLP
IFNLMSVLG

Nucleotide


Download         Length: 1230 bp        

>NTDB_id=1054433 BCV18_RS10445 WP_016768204.1 2248018..2249247(-) (pilC) [Vibrio cyclitrophicus strain 10N.286.54.F2]
ATGAGTAGTAAAAGCAAACAATCACAACTAAAAAACTACCATTGGAAGGGAATCAATAGTTCTGGCAAGAAAATGTCTGG
GCAGAGCTTAGCGCTCACCGAATTAGAAGTGCGAGAGAAGCTCAAAGAGCAACATATCCAAATTAAGAAAATCAAAAAGA
AAAGTATCTCCGCAATCACTCGTTTAACCCATAGAGTCAAAGCCAAAGACATCACTATTTTGACGAGACAGCTTGCTACC
ATGCTCGCTACGGGTGTGCCTATCGTGCAAGCCATAAAGTTGGTATCAGATAATCATCGTAAAGCAGAAATGAAATCTAT
TTTATCGCATATCTGCAAAGGTGTAGAAGCCGGAACGCCAATCTCAAAAGCAATGAGAACCGCAAGCCGCCACTTTGACG
ATCTCTACACCGACCTAGTCGCCACCGGAGAGCTTTCCGGCAACCTCGCACAAGTCTTTGAACGCTTAGCGACCTATCGT
GAAAAAAGTGAACAGTTAAAAGCTAAGGTGGTGAAAGCGCTTATCTATCCAGCAATGGTGGTCACGGTTGCGCTGACCGT
CTCCTATCTCATGCTCACCATGGTCATCCCAGAGTTTGAATCGATGTTTTCAGGCTTTGGTGCCGATCTTCCCTGGTTCA
CCCAACAAGTCCTCGACCTGTCTCATTGGATGCAAGCTTACAGTTTTTATACCGCCCTAGGCATCGGGGCTACCAGCCTG
GTTGTTCATCAACTGTGCCAACGTTCTTACTCGATTCGACTATCAGCCAGCCGCTTAGTGTTACGCTTTCCTGTACTAGG
TGGCGTAATGGCAAAGGCCTCTATCGCCAAGTTCAGCCGCACCTTATCAACCAGCTTTAGTTCTGGTATTCCGATTCTAA
TGAGCCTCAAAACTACAGCCAAAACCGCAGGCAGTCTGCATTATGAATCTGCGATCATCGAAGTACACCGAGAAACAGCC
GCGGGTATGCCGATGTATATTGCAATGCGCAATACCAATGCCTTCCCTGAAATGGTGTTACAGATGGTGATGATTGGTGA
AGAGTCAGGTAACCTTGATGATATGCTGAATAAAGTCGCTTCCATCTATGAGTTTGAAGTCGACAATACCGTCGACAACT
TAGGCAAAATTTTAGAGCCACTGATCATCGTGTTTTTAGGTACAGTTGTGGGTGGGCTTGTTGTCGCGATGTACTTACCA
ATCTTTAATCTTATGAGTGTGTTAGGATAG

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(278-400)

Type II secretion system (T2SS), protein F (T2SSF)

(75-197)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7Z1S1U0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Vibrio cholerae strain A1552

79.5

97.8

0.778
  pilC Vibrio campbellii strain DS40M4

73.775

99.756

0.736
  pilC Acinetobacter baylyi ADP1

42.054

100

0.421
  pilC Legionella pneumophila strain ERS1305867

42.145

98.044

0.413
  pilC Acinetobacter baumannii D1279779

41.584

98.778

0.411
  pilC Pseudomonas stutzeri DSM 10701

40.347

98.778

0.399
  pilG Neisseria gonorrhoeae MS11

40.05

98.289

0.394
  pilG Neisseria meningitidis 44/76-A

39.801

98.289

0.391

Multiple sequence alignment