Detailed information    

insolico Bioinformatically predicted

Overview


Name   comYC   Type   Machinery gene
Locus tag   ACEY2C_RS07445 Genome accession   NZ_CP169314
Coordinates   1546573..1546848 (-) Length   91 a.a.
NCBI ID   WP_029487321.1    Uniprot ID   -
Organism   Enterococcus gallinarum strain IFEGHNEK1     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Related MGE


Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 1508432..1564993 1546573..1546848 within 0


Gene organization within MGE regions


Location: 1508432..1564993
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACEY2C_RS07260 (ACEY2C_07260) - 1508480..1509973 (-) 1494 WP_005472834.1 phosphoglucomutase -
  ACEY2C_RS07265 (ACEY2C_07265) - 1510131..1510625 (-) 495 WP_003128475.1 methylated-DNA--[protein]-cysteine S-methyltransferase -
  ACEY2C_RS07270 (ACEY2C_07270) - 1510738..1512660 (-) 1923 WP_197081171.1 ABC transporter ATP-binding protein -
  ACEY2C_RS07275 (ACEY2C_07275) - 1512599..1514338 (-) 1740 WP_021149056.1 ABC transporter ATP-binding protein -
  ACEY2C_RS07280 (ACEY2C_07280) - 1514640..1516136 (-) 1497 WP_003128472.1 PASTA domain-containing protein -
  ACEY2C_RS07285 (ACEY2C_07285) - 1516129..1516803 (-) 675 WP_003128471.1 ABC transporter ATP-binding protein -
  ACEY2C_RS07290 (ACEY2C_07290) - 1516816..1518360 (-) 1545 WP_005472842.1 ABC transporter permease -
  ACEY2C_RS07295 (ACEY2C_07295) dtd 1518715..1519161 (-) 447 WP_003128467.1 D-aminoacyl-tRNA deacylase -
  ACEY2C_RS07300 (ACEY2C_07300) - 1519172..1521382 (-) 2211 WP_003128466.1 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase -
  ACEY2C_RS07305 (ACEY2C_07305) - 1521591..1522250 (-) 660 WP_123866838.1 deoxyribose-phosphate aldolase -
  ACEY2C_RS07310 (ACEY2C_07310) - 1522255..1523010 (-) 756 WP_005472847.1 16S rRNA (uracil(1498)-N(3))-methyltransferase -
  ACEY2C_RS07315 (ACEY2C_07315) prmA 1523021..1523962 (-) 942 WP_123866837.1 50S ribosomal protein L11 methyltransferase -
  ACEY2C_RS07320 (ACEY2C_07320) - 1523974..1524462 (-) 489 WP_003128461.1 DUF3013 family protein -
  ACEY2C_RS07325 (ACEY2C_07325) - 1524480..1525100 (-) 621 WP_005472850.1 DNA-3-methyladenine glycosylase -
  ACEY2C_RS07330 (ACEY2C_07330) - 1525277..1526554 (+) 1278 WP_005472852.1 replication-associated recombination protein A -
  ACEY2C_RS07340 (ACEY2C_07340) - 1526965..1527249 (+) 285 WP_005472853.1 hypothetical protein -
  ACEY2C_RS07345 (ACEY2C_07345) - 1527313..1527795 (+) 483 WP_003128457.1 universal stress protein -
  ACEY2C_RS07350 (ACEY2C_07350) - 1528170..1529750 (-) 1581 WP_003128454.1 hypothetical protein -
  ACEY2C_RS07355 (ACEY2C_07355) - 1529747..1530508 (-) 762 WP_005472856.1 ABC transporter ATP-binding protein -
  ACEY2C_RS07360 (ACEY2C_07360) - 1530780..1532786 (+) 2007 WP_374849445.1 KUP/HAK/KT family potassium transporter -
  ACEY2C_RS07365 (ACEY2C_07365) - 1532846..1532974 (+) 129 WP_005472862.1 hypothetical protein -
  ACEY2C_RS07370 (ACEY2C_07370) abc-f 1533078..1534661 (+) 1584 WP_005472864.1 ribosomal protection-like ABC-F family protein -
  ACEY2C_RS07375 (ACEY2C_07375) - 1534834..1535691 (-) 858 WP_005472866.1 radical SAM protein -
  ACEY2C_RS07380 (ACEY2C_07380) - 1535791..1537251 (-) 1461 WP_003128449.1 peptide MFS transporter -
  ACEY2C_RS07385 (ACEY2C_07385) - 1538242..1538583 (+) 342 WP_005472869.1 PadR family transcriptional regulator -
  ACEY2C_RS07390 (ACEY2C_07390) - 1538593..1539495 (+) 903 WP_374849449.1 ABC transporter ATP-binding protein -
  ACEY2C_RS07395 (ACEY2C_07395) - 1539499..1540278 (+) 780 WP_005472875.1 ABC transporter permease -
  ACEY2C_RS07400 (ACEY2C_07400) - 1540289..1540630 (+) 342 WP_003128445.1 DUF1048 domain-containing protein -
  ACEY2C_RS07405 (ACEY2C_07405) - 1540640..1540951 (+) 312 WP_005472877.1 DUF1048 domain-containing protein -
  ACEY2C_RS07410 (ACEY2C_07410) - 1541165..1542349 (-) 1185 WP_003128443.1 acetate/propionate family kinase -
  ACEY2C_RS07415 (ACEY2C_07415) - 1542374..1543381 (-) 1008 WP_029487317.1 class I SAM-dependent methyltransferase -
  ACEY2C_RS07420 (ACEY2C_07420) - 1543588..1544999 (+) 1412 WP_374849452.1 IS3 family transposase -
  ACEY2C_RS07425 (ACEY2C_07425) comGG 1545102..1545407 (-) 306 WP_238581784.1 competence type IV pilus minor pilin ComGG -
  ACEY2C_RS07430 (ACEY2C_07430) comGF 1545430..1545843 (-) 414 WP_003128440.1 competence type IV pilus minor pilin ComGF -
  ACEY2C_RS07435 (ACEY2C_07435) - 1545833..1546144 (-) 312 WP_029487319.1 hypothetical protein -
  ACEY2C_RS07440 (ACEY2C_07440) comGD 1546125..1546604 (-) 480 WP_003128438.1 competence type IV pilus minor pilin ComGD -
  ACEY2C_RS07445 (ACEY2C_07445) comYC 1546573..1546848 (-) 276 WP_029487321.1 competence type IV pilus major pilin ComGC Machinery gene
  ACEY2C_RS07450 (ACEY2C_07450) comGB 1546845..1547876 (-) 1032 WP_374849455.1 competence type IV pilus assembly protein ComGB -
  ACEY2C_RS07455 (ACEY2C_07455) comGA 1547851..1548792 (-) 942 WP_005472888.1 competence type IV pilus ATPase ComGA -
  ACEY2C_RS07460 (ACEY2C_07460) trmB 1548904..1549566 (-) 663 WP_003128433.1 tRNA (guanosine(46)-N7)-methyltransferase TrmB -
  ACEY2C_RS07465 (ACEY2C_07465) - 1549620..1550399 (-) 780 WP_003128432.1 phosphotransferase family protein -
  ACEY2C_RS07470 (ACEY2C_07470) - 1550504..1551715 (-) 1212 WP_029487323.1 ABC transporter permease -
  ACEY2C_RS07475 (ACEY2C_07475) - 1551712..1552446 (-) 735 WP_003128430.1 ABC transporter ATP-binding protein -
  ACEY2C_RS07480 (ACEY2C_07480) - 1552521..1553000 (-) 480 WP_003128429.1 hypothetical protein -
  ACEY2C_RS07485 (ACEY2C_07485) - 1553197..1553622 (+) 426 WP_005472896.1 HIT family protein -
  ACEY2C_RS07490 (ACEY2C_07490) - 1553623..1553988 (+) 366 WP_021149029.1 YtxH domain-containing protein -
  ACEY2C_RS07495 (ACEY2C_07495) - 1554116..1555144 (+) 1029 WP_003128425.1 peptidylprolyl isomerase -
  ACEY2C_RS07500 (ACEY2C_07500) - 1555183..1556127 (-) 945 WP_003128424.1 3'-5' exoribonuclease YhaM family protein -
  ACEY2C_RS07505 (ACEY2C_07505) - 1556156..1558816 (-) 2661 WP_005472902.1 AAA family ATPase -
  ACEY2C_RS07510 (ACEY2C_07510) - 1558813..1560000 (-) 1188 WP_003128421.1 DNA repair exonuclease -
  ACEY2C_RS07515 (ACEY2C_07515) - 1560265..1560606 (-) 342 WP_003128420.1 YlbF family regulator -
  ACEY2C_RS07520 (ACEY2C_07520) - 1560677..1562833 (-) 2157 WP_003128419.1 PBP1A family penicillin-binding protein -
  ACEY2C_RS07525 (ACEY2C_07525) - 1563027..1563878 (+) 852 WP_003128418.1 RluA family pseudouridine synthase -
  ACEY2C_RS07530 (ACEY2C_07530) - 1563971..1564696 (-) 726 WP_003128417.1 pseudouridine synthase -

Sequence


Protein


Download         Length: 91 a.a.        Molecular weight: 10464.26 Da        Isoelectric Point: 6.4633

>NTDB_id=1050433 ACEY2C_RS07445 WP_029487321.1 1546573..1546848(-) (comYC) [Enterococcus gallinarum strain IFEGHNEK1]
MRKLKHQGFTLVEMLIVLLVISILILLFVPNLSAQRTVIDEKGNAAIVKVVETQIELFQLNENRTPTRQELLAGNYVTEE
QYAIYLAHRNE

Nucleotide


Download         Length: 276 bp        

>NTDB_id=1050433 ACEY2C_RS07445 WP_029487321.1 1546573..1546848(-) (comYC) [Enterococcus gallinarum strain IFEGHNEK1]
ATGAGAAAATTGAAGCATCAAGGGTTCACATTGGTGGAGATGCTGATTGTACTGTTAGTGATCAGTATTTTGATTTTATT
GTTTGTACCAAACTTATCCGCACAACGTACAGTGATAGATGAGAAAGGAAATGCGGCAATCGTCAAAGTCGTAGAAACCC
AGATTGAGTTGTTCCAGCTTAATGAGAATCGAACACCTACTCGACAAGAATTACTAGCTGGAAATTATGTAACGGAGGAG
CAGTATGCGATTTACCTTGCCCATCGGAACGAATAG


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYC Streptococcus suis isolate S10

51.613

100

0.527

  comGC/cglC Streptococcus mitis NCTC 12261

50.538

100

0.516

  comYC Streptococcus mutans UA159

48.387

100

0.495

  comYC Streptococcus mutans UA140

48.387

100

0.495

  comGC/cglC Streptococcus pneumoniae TIGR4

48.352

100

0.484

  comGC/cglC Streptococcus pneumoniae Rx1

48.352

100

0.484

  comGC/cglC Streptococcus pneumoniae D39

48.352

100

0.484

  comGC/cglC Streptococcus pneumoniae R6

48.352

100

0.484

  comGC/cglC Streptococcus mitis SK321

51.765

93.407

0.484

  comGC Lactococcus lactis subsp. cremoris KW2

50

96.703

0.484

  comYC Streptococcus gordonii str. Challis substr. CH1

48.315

97.802

0.473

  comGC Staphylococcus aureus MW2

44.872

85.714

0.385

  comGC Staphylococcus aureus N315

44.872

85.714

0.385


Multiple sequence alignment