Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   AB9L16_RS21910 Genome accession   NZ_CP168138
Coordinates   4852595..4853812 (+) Length   405 a.a.
NCBI ID   WP_150638505.1    Uniprot ID   A0A5E7NZ39
Organism   Pseudomonas sp. LW8     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 4847595..4858812
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AB9L16_RS21890 (AB9L16_21890) - 4849030..4849329 (+) 300 WP_095181833.1 DUF2845 domain-containing protein -
  AB9L16_RS21895 (AB9L16_21895) - 4849594..4849947 (-) 354 WP_071173629.1 BON domain-containing protein -
  AB9L16_RS21900 (AB9L16_21900) pilA/pilAI 4850243..4850665 (-) 423 WP_252876912.1 pilin Machinery gene
  AB9L16_RS21905 (AB9L16_21905) pilB 4850892..4852592 (+) 1701 WP_056790439.1 type IV-A pilus assembly ATPase PilB Machinery gene
  AB9L16_RS21910 (AB9L16_21910) pilC 4852595..4853812 (+) 1218 WP_150638505.1 type II secretion system F family protein Machinery gene
  AB9L16_RS21915 (AB9L16_21915) pilD 4853814..4854686 (+) 873 WP_252876914.1 A24 family peptidase Machinery gene
  AB9L16_RS21920 (AB9L16_21920) coaE 4854683..4855306 (+) 624 WP_252876915.1 dephospho-CoA kinase -
  AB9L16_RS21925 (AB9L16_21925) yacG 4855303..4855503 (+) 201 WP_016773149.1 DNA gyrase inhibitor YacG -
  AB9L16_RS21930 (AB9L16_21930) - 4855511..4855726 (-) 216 WP_016773148.1 hypothetical protein -
  AB9L16_RS21935 (AB9L16_21935) - 4855792..4856481 (-) 690 WP_041477814.1 energy-coupling factor ABC transporter permease -
  AB9L16_RS21940 (AB9L16_21940) - 4856672..4857298 (+) 627 WP_007909887.1 DUF1780 domain-containing protein -
  AB9L16_RS21945 (AB9L16_21945) - 4857295..4857822 (+) 528 WP_095181837.1 MOSC domain-containing protein -
  AB9L16_RS21950 (AB9L16_21950) - 4857874..4858047 (+) 174 WP_007909875.1 DUF3094 domain-containing protein -

Sequence

Protein


Download         Length: 405 a.a.        Molecular weight: 44057.75 Da        Isoelectric Point: 10.1214

>NTDB_id=1042507 AB9L16_RS21910 WP_150638505.1 4852595..4853812(+) (pilC) [Pseudomonas sp. LW8]
MAVKAAKVSIYAWEGTDRKGSKVSGELSGQNPALIKAQLRKQGINPGKVRKKSASLLTFGKRIKPQDIALFTRQMATMMK
AGVPLLQSFDIIGEGFENPAMRKLVDEVKQEVAAGNSFATALRKKPQYFDELYCNLVDAGEQSGALDTLLERVATYKEKS
EALKAKIKKAMTYPTAVVLVAAVVTGILLVKVVPQFQSVFSGFGAELPGFTLMIISLSEFMQQWWWAILFALVAAFFGTR
HALKTSQALRDRRDAWLLKLPLVGTLMYKSAVARFARTLSTTFAAGVPLVEALDSVAGATGNVVFKRAVLRVRQDVSTGM
QLNFSMRSTGVFPNMAVQMTAIGEESGALDDMLDKVAGFYEAEVDNMVDNLTSLMEPFIMVVLGVIVGGLVVAMYLPIFQ
LGSAI

Nucleotide


Download         Length: 1218 bp        

>NTDB_id=1042507 AB9L16_RS21910 WP_150638505.1 4852595..4853812(+) (pilC) [Pseudomonas sp. LW8]
ATGGCGGTCAAGGCAGCGAAAGTCAGCATTTACGCCTGGGAAGGCACGGACCGCAAAGGCAGTAAAGTCAGCGGCGAGTT
GAGCGGACAGAACCCCGCACTGATCAAGGCGCAACTGCGCAAACAGGGGATCAACCCGGGCAAGGTGCGCAAGAAATCCG
CGTCCCTGCTGACCTTCGGCAAACGCATCAAACCGCAGGACATCGCCCTGTTCACCCGGCAGATGGCAACGATGATGAAG
GCCGGTGTACCGCTGTTGCAGTCCTTCGACATCATCGGCGAAGGCTTCGAAAATCCGGCCATGCGCAAACTGGTCGACGA
GGTCAAACAGGAGGTCGCGGCCGGTAACAGCTTCGCTACGGCCCTGCGCAAGAAACCACAATACTTCGACGAGTTGTACT
GCAATCTGGTCGACGCCGGCGAACAGTCTGGCGCCCTCGACACCTTGCTTGAACGTGTGGCGACCTATAAGGAAAAAAGC
GAAGCGCTCAAGGCCAAGATCAAAAAAGCCATGACCTACCCCACCGCCGTGGTGCTGGTGGCGGCAGTGGTAACAGGCAT
TCTGCTGGTCAAGGTGGTGCCGCAGTTCCAGTCGGTATTCTCCGGGTTCGGCGCCGAACTGCCGGGCTTCACCCTGATGA
TCATCAGCCTGTCGGAATTCATGCAGCAGTGGTGGTGGGCGATTCTTTTTGCGCTGGTGGCAGCGTTTTTCGGCACTCGC
CACGCGCTGAAGACATCGCAGGCCCTGCGTGACCGCCGCGATGCCTGGCTGTTGAAGCTGCCACTGGTGGGCACCTTGAT
GTACAAGTCCGCCGTCGCACGTTTTGCCCGCACCCTGTCGACCACATTCGCAGCCGGTGTGCCGCTGGTGGAAGCACTGG
ATTCGGTCGCCGGTGCCACCGGCAATGTGGTGTTCAAGCGCGCGGTGTTGCGGGTGCGGCAGGACGTCTCGACCGGCATG
CAACTGAATTTCTCCATGCGCAGCACCGGTGTGTTTCCCAACATGGCGGTGCAGATGACCGCCATCGGCGAGGAATCGGG
CGCGCTGGATGACATGCTCGACAAGGTCGCCGGTTTTTATGAAGCGGAAGTCGATAACATGGTCGACAACCTCACCAGCC
TGATGGAGCCGTTCATCATGGTGGTGCTGGGGGTCATCGTCGGTGGACTGGTGGTGGCCATGTACCTGCCGATCTTCCAA
CTCGGCTCAGCGATCTGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(275-397)

Type II secretion system (T2SS), protein F (T2SSF)

(71-194)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A5E7NZ39

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

73.827

100

0.738
  pilC Acinetobacter baylyi ADP1

58.578

100

0.59
  pilC Acinetobacter baumannii D1279779

58.578

100

0.59
  pilC Legionella pneumophila strain ERS1305867

52.75

98.765

0.521
  pilC Vibrio cholerae strain A1552

44.697

97.778

0.437
  pilG Neisseria gonorrhoeae MS11

43.424

99.506

0.432
  pilG Neisseria meningitidis 44/76-A

42.68

99.506

0.425
  pilC Vibrio campbellii strain DS40M4

41.872

100

0.42
  pilC Thermus thermophilus HB27

39.348

98.519

0.388

Multiple sequence alignment