Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYC   Type   Machinery gene
Locus tag   ACB348_RS00780 Genome accession   NZ_CP167002
Coordinates   117928..118254 (+) Length   108 a.a.
NCBI ID   WP_032465607.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain Isolate 30     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 112928..123254
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACB348_RS00765 (ACB348_00765) - 115560..115925 (+) 366 WP_002986560.1 DUF1033 family protein -
  ACB348_RS00770 (ACB348_00770) comYA 116018..116956 (+) 939 WP_111704879.1 competence type IV pilus ATPase ComGA Machinery gene
  ACB348_RS00775 (ACB348_00775) comYB 116892..117926 (+) 1035 WP_011054115.1 competence type IV pilus assembly protein ComGB Machinery gene
  ACB348_RS00780 (ACB348_00780) comYC 117928..118254 (+) 327 WP_032465607.1 competence type IV pilus major pilin ComGC Machinery gene
  ACB348_RS00785 (ACB348_00785) comGD 118229..118657 (+) 429 WP_002986548.1 competence type IV pilus minor pilin ComGD -
  ACB348_RS00790 (ACB348_00790) comGE 118614..118898 (+) 285 WP_002987779.1 competence type IV pilus minor pilin ComGE -
  ACB348_RS00795 (ACB348_00795) comYF 118891..119325 (+) 435 WP_023612536.1 competence type IV pilus minor pilin ComGF Machinery gene
  ACB348_RS00800 (ACB348_00800) comGG 119309..119635 (+) 327 WP_002992739.1 competence type IV pilus minor pilin ComGG -
  ACB348_RS00805 (ACB348_00805) comYH 119733..120686 (+) 954 WP_002987790.1 class I SAM-dependent methyltransferase Machinery gene
  ACB348_RS00810 (ACB348_00810) - 120745..121941 (+) 1197 WP_023612537.1 acetate kinase -
  ACB348_RS00815 (ACB348_00815) - 122128..122436 (+) 309 WP_030126458.1 hypothetical protein -

Sequence

Protein


Download         Length: 108 a.a.        Molecular weight: 12375.38 Da        Isoelectric Point: 10.0732

>NTDB_id=1036901 ACB348_RS00780 WP_032465607.1 117928..118254(+) (comYC) [Streptococcus pyogenes strain Isolate 30]
MINQWNNLRHKKLKGFTLLEMLLVILVISVLMLLFVPNLSKQKDRVTETGNAAVVKLVENQAELYELSQGSKPSLSQLKA
DGSITEKQEKAYQDYYNKHKNEKARLSN

Nucleotide


Download         Length: 327 bp        

>NTDB_id=1036901 ACB348_RS00780 WP_032465607.1 117928..118254(+) (comYC) [Streptococcus pyogenes strain Isolate 30]
ATGATTAATCAATGGAACAACTTACGACACAAGAAGCTAAAAGGATTTACTCTTCTAGAAATGTTATTGGTGATTCTTGT
CATCAGTGTTTTGATGCTATTATTTGTGCCTAATTTAAGCAAGCAAAAAGACAGGGTTACAGAAACAGGTAATGCCGCTG
TTGTTAAATTAGTGGAGAATCAAGCAGAACTATATGAATTATCTCAAGGCTCAAAACCAAGTTTGAGCCAGTTAAAGGCA
GATGGTAGTATCACTGAGAAACAAGAAAAAGCTTATCAAGACTATTATAACAAACATAAAAATGAAAAAGCCCGTCTTAG
CAATTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(12-34)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYC Streptococcus gordonii str. Challis substr. CH1

56.19

97.222

0.546
  comGC/cglC Streptococcus mitis SK321

61.957

85.185

0.528
  comGC Lactococcus lactis subsp. cremoris KW2

55.882

94.444

0.528
  comGC/cglC Streptococcus mitis NCTC 12261

60.87

85.185

0.519
  comGC/cglC Streptococcus pneumoniae TIGR4

59.783

85.185

0.509
  comGC/cglC Streptococcus pneumoniae Rx1

59.783

85.185

0.509
  comGC/cglC Streptococcus pneumoniae D39

59.783

85.185

0.509
  comGC/cglC Streptococcus pneumoniae R6

59.783

85.185

0.509
  comYC Streptococcus mutans UA140

55.208

88.889

0.491
  comYC Streptococcus mutans UA159

55.208

88.889

0.491
  comYC Streptococcus suis isolate S10

59.259

75

0.444

Multiple sequence alignment