Detailed information NTG1036902

Bioinformatically predicted

Overview

• Name: comYF
• Type: Machinery gene
• Locus tag: ACB348_RS00795
• Genome accession: NZ_CP167002
• Coordinates: 118891..119325 (+)
• Length: 144 a.a.
• NCBI ID: WP_023612536.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain Isolate 30
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 113891..124325

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACB348_RS00765 (ACB348_00765)	-	115560..115925 (+)	366	WP_002986560.1	DUF1033 family protein	-
ACB348_RS00770 (ACB348_00770)	comYA	116018..116956 (+)	939	WP_111704879.1	competence type IV pilus ATPase ComGA	Machinery gene
ACB348_RS00775 (ACB348_00775)	comYB	116892..117926 (+)	1035	WP_011054115.1	competence type IV pilus assembly protein ComGB	Machinery gene
ACB348_RS00780 (ACB348_00780)	comYC	117928..118254 (+)	327	WP_032465607.1	competence type IV pilus major pilin ComGC	Machinery gene
ACB348_RS00785 (ACB348_00785)	comGD	118229..118657 (+)	429	WP_002986548.1	competence type IV pilus minor pilin ComGD	-
ACB348_RS00790 (ACB348_00790)	comGE	118614..118898 (+)	285	WP_002987779.1	competence type IV pilus minor pilin ComGE	-
ACB348_RS00795 (ACB348_00795)	comYF	118891..119325 (+)	435	WP_023612536.1	competence type IV pilus minor pilin ComGF	Machinery gene
ACB348_RS00800 (ACB348_00800)	comGG	119309..119635 (+)	327	WP_002992739.1	competence type IV pilus minor pilin ComGG	-
ACB348_RS00805 (ACB348_00805)	comYH	119733..120686 (+)	954	WP_002987790.1	class I SAM-dependent methyltransferase	Machinery gene
ACB348_RS00810 (ACB348_00810)	-	120745..121941 (+)	1197	WP_023612537.1	acetate kinase	-
ACB348_RS00815 (ACB348_00815)	-	122128..122436 (+)	309	WP_030126458.1	hypothetical protein	-
ACB348_RS00820 (ACB348_00820)	proC	122519..123289 (-)	771	WP_002986527.1	pyrroline-5-carboxylate reductase	-

Sequence

Protein

• Length: 144 a.a.
• Molecular weight: 16688.29 Da
• Isoelectric Point: 10.2526

>NTDB_id=1036902 ACB348_RS00795 WP_023612536.1 118891..119325(+) (comYF) [Streptococcus pyogenes strain Isolate 30]
MSKQLSNIKAFTFLEALIALLVISGSLLVYQGLTRTLLKHSHYLARHDQDNWLLFSHQLREELSGARFYKVADNKLYVEK
GKKVLAFGQFKSHDFRKSASNGKGYQPMLFGISRSHIHIEQSQICITLKWKSGLERTFYYAFQD

Nucleotide

• Length: 435 bp

>NTDB_id=1036902 ACB348_RS00795 WP_023612536.1 118891..119325(+) (comYF) [Streptococcus pyogenes strain Isolate 30]
TTGAGTAAACAATTAAGTAACATAAAAGCTTTTACCTTTCTAGAGGCGTTAATAGCCTTACTCGTGATATCAGGGTCTTT
ATTGGTTTATCAAGGTTTGACCCGAACCCTCCTTAAACATAGCCATTATCTAGCCCGTCATGATCAAGATAATTGGCTCT
TATTTTCTCATCAATTGCGAGAGGAGTTAAGTGGAGCAAGATTTTACAAAGTAGCTGATAATAAACTATACGTTGAAAAA
GGAAAGAAAGTACTAGCTTTTGGCCAATTTAAAAGTCATGATTTTCGAAAATCAGCTAGTAATGGAAAAGGGTATCAACC
CATGTTATTTGGAATATCACGTAGTCATATTCACATAGAGCAGTCACAGATTTGCATTACTTTAAAGTGGAAAAGTGGGT
TAGAAAGGACTTTTTATTATGCCTTTCAAGACTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (41-135)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYF	Streptococcus mutans UA140	50.36	96.528	0.486
comYF	Streptococcus mutans UA159	49.64	96.528	0.479
comGF	Lactococcus lactis subsp. cremoris KW2	46.715	95.139	0.444
comGF/cglF	Streptococcus mitis NCTC 12261	43.284	93.056	0.403
comGF/cglF	Streptococcus pneumoniae Rx1	42.105	92.361	0.389
comGF/cglF	Streptococcus pneumoniae D39	42.105	92.361	0.389
comGF/cglF	Streptococcus pneumoniae R6	42.105	92.361	0.389
comGF/cglF	Streptococcus pneumoniae TIGR4	42.105	92.361	0.389
comGF/cglF	Streptococcus mitis SK321	41.353	92.361	0.382