Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   ACA346_RS00410 Genome accession   NZ_CP166970
Coordinates   73282..74463 (+) Length   393 a.a.
NCBI ID   WP_217374496.1    Uniprot ID   -
Organism   Streptococcus parasuis strain NX1     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 68282..79463
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACA346_RS00395 (ACA346_00395) mutL 69378..71315 (+) 1938 WP_418127489.1 DNA mismatch repair endonuclease MutL -
  ACA346_RS00400 (ACA346_00400) ruvA 71561..72151 (+) 591 WP_418126909.1 Holliday junction branch migration protein RuvA -
  ACA346_RS00405 (ACA346_00405) - 72676..73245 (+) 570 WP_217374495.1 DNA-3-methyladenine glycosylase I -
  ACA346_RS00410 (ACA346_00410) cinA 73282..74463 (+) 1182 WP_217374496.1 competence/damage-inducible protein A Machinery gene
  ACA346_RS00415 (ACA346_00415) recA 74515..75669 (+) 1155 WP_418126910.1 recombinase RecA Machinery gene
  ACA346_RS00420 (ACA346_00420) spx 75883..76281 (+) 399 WP_217374497.1 transcriptional regulator Spx -
  ACA346_RS00425 (ACA346_00425) - 76391..76657 (+) 267 WP_130554425.1 IreB family regulatory phosphoprotein -
  ACA346_RS00430 (ACA346_00430) ruvX 76657..77076 (+) 420 WP_130554426.1 Holliday junction resolvase RuvX -
  ACA346_RS00435 (ACA346_00435) - 77088..77408 (+) 321 WP_024392832.1 DUF1292 domain-containing protein -
  ACA346_RS00440 (ACA346_00440) - 77713..77853 (+) 141 Protein_67 ISL3 family transposase -
  ACA346_RS00445 (ACA346_00445) - 77883..78431 (+) 549 WP_418126911.1 nucleotidyltransferase family protein -
  ACA346_RS00450 (ACA346_00450) comX/sigX 78614..79084 (+) 471 WP_130554428.1 sigma-70 family RNA polymerase sigma factor Regulator

Sequence

Protein


Download         Length: 393 a.a.        Molecular weight: 42726.70 Da        Isoelectric Point: 4.4569

>NTDB_id=1036412 ACA346_RS00410 WP_217374496.1 73282..74463(+) (cinA) [Streptococcus parasuis strain NX1]
MKAELIAVGTEILTGQIVNTNAQFLSEKCAELGIDVYFHTAVGDNEQRLLSVLEIASKRSDLVILCGGLGPTEDDLTKQT
LATFLQKELVVDELAMAKLDRFFASRPGRVRTPNNERQAQIVEGSQALQNPAGLAVGGMIEQDGVTYIVLPGPPSELKAM
FSESLLPFLTQSQQQLYSRVLRFFGIGESQLVTVLADLIDKQTDPTIAPYAKVGEVTLRLSTKADSQEEANVRLNQLEEE
ILQRDHLRVFFYAYGDDNSLVKTVATLLEEKKQSLGILENGTGGLLQAELSLALAGQPYYSGGKIIGQLGTESGGLSEEA
SRIREELQADLGLVVSVAVKPESTVDNVLAKVYLALASTSGISKKEVDLGGYSWQYLRQLACLQALDFVRNTL

Nucleotide


Download         Length: 1182 bp        

>NTDB_id=1036412 ACA346_RS00410 WP_217374496.1 73282..74463(+) (cinA) [Streptococcus parasuis strain NX1]
ATGAAAGCAGAATTAATTGCTGTTGGAACAGAAATATTGACAGGTCAAATTGTGAATACGAATGCTCAATTCTTGTCAGA
AAAATGTGCAGAGCTAGGTATCGATGTATACTTCCATACTGCTGTAGGTGATAATGAACAGCGACTATTGTCTGTACTTG
AAATTGCAAGTAAACGAAGTGATCTGGTCATTTTATGTGGTGGTTTAGGTCCTACTGAAGACGACTTGACCAAGCAAACT
TTAGCGACATTTTTGCAAAAAGAGTTGGTTGTTGACGAACTAGCGATGGCAAAATTAGACCGTTTTTTTGCCAGTCGACC
AGGTCGTGTTCGCACACCTAATAATGAGCGTCAAGCACAGATTGTGGAGGGAAGTCAGGCGCTACAGAACCCAGCTGGTT
TAGCTGTAGGTGGTATGATTGAGCAAGATGGTGTGACCTATATTGTTTTGCCTGGCCCACCAAGTGAACTCAAGGCCATG
TTTTCTGAGAGTCTGTTACCTTTTTTGACTCAATCTCAGCAACAACTTTACTCGCGTGTCCTACGCTTTTTTGGAATAGG
TGAAAGCCAGTTGGTGACTGTTTTAGCGGATTTGATTGACAAGCAGACAGACCCGACTATTGCGCCTTATGCAAAAGTTG
GAGAGGTGACGCTTCGTTTATCTACAAAGGCAGATAGCCAGGAAGAAGCGAACGTGCGTTTGAATCAGTTGGAAGAAGAG
ATATTGCAACGTGACCATTTGAGAGTTTTTTTCTATGCATATGGGGATGATAATAGTTTGGTTAAAACCGTAGCGACTCT
TTTAGAGGAAAAGAAACAATCTTTGGGCATCCTAGAGAATGGAACAGGTGGTTTATTACAAGCAGAATTGAGTCTGGCTT
TGGCTGGTCAGCCGTATTATAGTGGAGGAAAAATCATCGGTCAGCTAGGGACAGAATCGGGCGGGCTATCAGAAGAAGCA
AGTCGCATTCGGGAGGAACTACAAGCTGATTTAGGGCTAGTTGTGTCGGTGGCAGTCAAACCAGAATCAACAGTAGACAA
CGTACTTGCTAAAGTATATCTAGCCTTGGCCAGTACCTCGGGTATTTCTAAAAAAGAGGTAGATTTAGGAGGTTATTCAT
GGCAATACCTTCGTCAACTTGCTTGTTTACAGGCGTTAGATTTTGTACGAAACACTTTGTGA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-244)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus suis isolate S10

87.023

100

0.87
  cinA Streptococcus mitis SK321

55.288

100

0.585
  cinA Streptococcus mitis NCTC 12261

55.048

100

0.583
  cinA Streptococcus pneumoniae TIGR4

54.808

100

0.58
  cinA Streptococcus pneumoniae Rx1

54.808

100

0.58
  cinA Streptococcus pneumoniae R6

54.808

100

0.58
  cinA Streptococcus mutans UA159

55.474

100

0.58
  cinA Streptococcus pneumoniae D39

54.567

100

0.578
  cinA Bacillus subtilis subsp. subtilis str. 168

47.869

77.608

0.372

Multiple sequence alignment