Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   AB6N02_RS01020 Genome accession   NZ_CP163510
Coordinates   202753..203994 (+) Length   413 a.a.
NCBI ID   WP_010675822.1    Uniprot ID   A0A2L0TT63
Organism   Aeromonas caviae strain 103     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 197753..208994
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AB6N02_RS00995 (AB6N02_00995) ampD 198181..198753 (-) 573 WP_039040507.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  AB6N02_RS01000 (AB6N02_01000) - 198882..199352 (+) 471 WP_042015101.1 TIGR02281 family clan AA aspartic protease -
  AB6N02_RS01005 (AB6N02_01005) nadC 199356..200219 (+) 864 WP_052814467.1 carboxylating nicotinate-nucleotide diphosphorylase -
  AB6N02_RS01010 (AB6N02_01010) - 200380..200919 (+) 540 WP_270825191.1 prepilin-type N-terminal cleavage/methylation domain-containing protein -
  AB6N02_RS01015 (AB6N02_01015) pilB 200919..202625 (+) 1707 WP_052814466.1 PilB family type IVa pilus assembly ATPase TapB Machinery gene
  AB6N02_RS01020 (AB6N02_01020) pilC 202753..203994 (+) 1242 WP_010675822.1 type II secretion system F family protein Machinery gene
  AB6N02_RS01025 (AB6N02_01025) pilD 204072..204947 (+) 876 WP_052814465.1 A24 family peptidase Machinery gene
  AB6N02_RS01030 (AB6N02_01030) coaE 204966..205580 (+) 615 WP_369325401.1 dephospho-CoA kinase -
  AB6N02_RS01035 (AB6N02_01035) zapD 205618..206340 (+) 723 WP_010675825.1 cell division protein ZapD -
  AB6N02_RS01040 (AB6N02_01040) yacG 206351..206545 (+) 195 WP_039040499.1 DNA gyrase inhibitor YacG -
  AB6N02_RS01045 (AB6N02_01045) mutT 206603..207007 (-) 405 WP_174213873.1 8-oxo-dGTP diphosphatase MutT -
  AB6N02_RS01050 (AB6N02_01050) - 207016..208200 (-) 1185 WP_049637195.1 tetratricopeptide repeat protein -

Sequence

Protein


Download         Length: 413 a.a.        Molecular weight: 45435.37 Da        Isoelectric Point: 9.9380

>NTDB_id=1030211 AB6N02_RS01020 WP_010675822.1 202753..203994(+) (pilC) [Aeromonas caviae strain 103]
MATLAQKRNAPKKVFSYRWHGVNRKGQKVSGELQADSITTVKAELRKQGVNVTRVSKQSQGLFSKGGAKIKPMDIAVISR
QITTMLSAGVPLVQSLQIIARGHEKAAVRELIGQIAADVETGTPLSEALRRHPRHFDDLYCDLVEAGEQSGALETIYDRI
AIYREKNEALKSKIKKAMFYPSMVILVAIVVTSILLLFVIPQFEDIFKSFGAELPAFTRFVIAISRFMQEWWYAIFGGAA
LAVFLYVRAWRKSQKVRDNTDKFILTIPVVGNILHKAAMARFARTLSTTFSAGIPLVDALVSAAGASGNYVYRTATMAIR
NEVVAGMQINVAMRTVDLFPDMVTQMVMIGEESGAIDDMLSKVAAIFEQEVDDMVDGLTSLLEPIIMVVLGVLVGGMVVA
MYLPIFKLGSVIH

Nucleotide


Download         Length: 1242 bp        

>NTDB_id=1030211 AB6N02_RS01020 WP_010675822.1 202753..203994(+) (pilC) [Aeromonas caviae strain 103]
ATGGCCACATTAGCTCAAAAACGCAACGCACCGAAAAAAGTCTTCTCCTACCGCTGGCACGGCGTCAACCGCAAGGGACA
GAAGGTCTCCGGCGAGCTGCAAGCCGACAGCATCACCACCGTCAAGGCCGAGCTGCGCAAGCAGGGCGTCAACGTCACCA
GGGTCAGCAAGCAGAGCCAGGGGCTCTTCTCCAAGGGCGGCGCCAAGATCAAGCCGATGGACATCGCCGTCATCTCCCGC
CAGATCACCACCATGCTCTCCGCCGGCGTGCCTCTGGTGCAGAGTCTTCAGATCATTGCTCGCGGCCACGAGAAAGCGGC
GGTGCGCGAACTCATCGGCCAGATCGCCGCCGATGTGGAAACGGGCACCCCGCTCTCGGAGGCGTTGCGCCGCCATCCCC
GCCACTTCGACGACCTCTATTGCGACCTGGTCGAGGCCGGGGAGCAATCCGGTGCCCTGGAGACCATCTACGACCGTATC
GCCATCTACCGCGAGAAGAACGAAGCCCTCAAATCCAAGATCAAGAAGGCCATGTTCTATCCGTCCATGGTCATTCTGGT
GGCCATCGTCGTCACCTCCATCCTGCTGCTCTTCGTCATTCCCCAGTTCGAGGATATCTTCAAGAGCTTCGGTGCCGAGC
TGCCCGCCTTTACCCGGTTCGTCATCGCCATCTCCCGCTTCATGCAGGAGTGGTGGTACGCCATCTTTGGCGGCGCGGCT
CTCGCCGTCTTCCTCTATGTGCGGGCCTGGCGAAAATCCCAGAAGGTCAGGGACAACACGGACAAGTTCATCCTCACCAT
TCCCGTGGTGGGCAACATACTGCACAAGGCGGCCATGGCCCGTTTTGCACGCACCCTCTCCACCACCTTCTCCGCCGGTA
TCCCACTGGTGGATGCCCTGGTCTCGGCGGCCGGAGCATCGGGCAACTATGTCTATCGCACTGCGACCATGGCCATTCGC
AACGAGGTGGTGGCCGGCATGCAGATCAACGTCGCCATGCGCACCGTGGATCTTTTCCCCGACATGGTGACCCAGATGGT
GATGATCGGTGAGGAATCCGGCGCCATCGACGACATGCTCTCCAAGGTCGCCGCCATTTTCGAACAGGAGGTGGACGACA
TGGTCGACGGCCTCACCAGCCTGCTCGAACCCATCATCATGGTGGTGCTCGGGGTGCTGGTCGGCGGCATGGTCGTGGCC
ATGTACCTCCCCATTTTCAAGCTGGGCTCTGTGATACACTGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(79-201)

Type II secretion system (T2SS), protein F (T2SSF)

(282-404)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2L0TT63

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

56.566

95.884

0.542
  pilC Legionella pneumophila strain ERS1305867

52.099

98.063

0.511
  pilC Acinetobacter baylyi ADP1

50.971

99.758

0.508
  pilC Acinetobacter baumannii D1279779

52.369

97.094

0.508
  pilC Vibrio cholerae strain A1552

47.368

96.61

0.458
  pilC Vibrio campbellii strain DS40M4

45.113

96.61

0.436
  pilG Neisseria meningitidis 44/76-A

41.602

93.705

0.39
  pilG Neisseria gonorrhoeae MS11

41.602

93.705

0.39
  pilC Thermus thermophilus HB27

38.75

96.852

0.375

Multiple sequence alignment