Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/comE2   Type   Regulator
Locus tag   AB4X21_RS10050 Genome accession   NZ_CP163380
Coordinates   2046427..2047185 (-) Length   252 a.a.
NCBI ID   WP_151379380.1    Uniprot ID   -
Organism   Streptococcus sp. CP1998     
Function   activate transcription of early competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2041427..2052185
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AB4X21_RS10030 (AB4X21_10030) - 2041878..2043503 (+) 1626 WP_151379381.1 ATP-binding cassette domain-containing protein -
  AB4X21_RS10035 (AB4X21_10035) - 2043553..2046120 (+) 2568 WP_369087940.1 YfhO family protein -
  AB4X21_RS10050 (AB4X21_10050) comE/comE2 2046427..2047185 (-) 759 WP_151379380.1 LytTR family DNA-binding domain-containing protein Regulator
  AB4X21_RS10055 (AB4X21_10055) - 2047182..2048522 (-) 1341 WP_270300096.1 GHKL domain-containing protein -
  AB4X21_RS10065 (AB4X21_10065) rlmH 2048985..2049464 (-) 480 WP_369087941.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  AB4X21_RS10070 (AB4X21_10070) htrA 2049669..2050850 (+) 1182 WP_151379379.1 S1C family serine protease Regulator
  AB4X21_RS10075 (AB4X21_10075) spo0J 2050922..2051683 (+) 762 WP_369087942.1 ParB/RepB/Spo0J family partition protein Regulator

Sequence

Protein


Download         Length: 252 a.a.        Molecular weight: 29678.24 Da        Isoelectric Point: 5.7562

>NTDB_id=1029451 AB4X21_RS10050 WP_151379380.1 2046427..2047185(-) (comE/comE2) [Streptococcus sp. CP1998]
MKIFLLEDELSQQIRVEKHIVEIAKELEIKLEVISTGKLTEFENYIQHSDIHQLYFLDIHIQDNEYCGLEIAKKIRETNP
YAIIVFITTKSEFASITYRYKVSALDFIDKNLNEDLFRLKIKECIEYLTTIQIGNDDLTDYFEYDFKDKKIKIPFKDILY
IETVGSAYKLNLVGKNFQKEIAGSLSDVLEKDVEERYFSPHQSYIVNRSMIVGMDKKRKQLLLKEGYSCPISRSNIKRVK
KLIEEQNLEFSA

Nucleotide


Download         Length: 759 bp        

>NTDB_id=1029451 AB4X21_RS10050 WP_151379380.1 2046427..2047185(-) (comE/comE2) [Streptococcus sp. CP1998]
ATGAAGATTTTTTTATTAGAAGATGAGCTCTCTCAACAGATACGGGTAGAAAAACATATTGTAGAAATTGCTAAAGAATT
AGAAATTAAACTTGAAGTGATTTCTACCGGTAAACTTACGGAATTTGAAAATTATATCCAACATTCGGATATCCACCAAT
TATATTTTCTAGATATTCATATCCAAGACAATGAATATTGTGGGCTAGAAATTGCTAAAAAAATACGAGAAACAAATCCT
TATGCCATTATTGTTTTTATTACTACAAAATCAGAATTCGCTTCTATTACCTATCGTTATAAAGTATCTGCCTTGGATTT
TATTGATAAAAATTTGAATGAAGATTTATTTAGATTAAAAATAAAGGAGTGTATTGAGTATCTAACAACTATTCAAATTG
GAAATGATGATTTGACAGATTATTTTGAGTATGACTTTAAGGATAAAAAGATAAAAATTCCATTTAAGGATATTCTTTAT
ATTGAGACTGTTGGTTCGGCTTATAAATTAAACTTAGTTGGGAAAAATTTTCAAAAAGAAATTGCGGGAAGTTTATCAGA
TGTCTTGGAGAAAGATGTGGAGGAGAGATATTTCAGTCCCCATCAATCTTATATCGTAAATAGAAGTATGATCGTTGGGA
TGGATAAGAAAAGAAAACAGTTGTTGTTGAAAGAAGGGTATTCTTGTCCAATCTCAAGAAGCAATATCAAACGTGTCAAA
AAATTAATTGAAGAGCAAAATTTAGAATTTAGTGCTTGA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(149-243)

Response regulator receiver domain (Response_reg)

(30-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/comE2 Streptococcus gordonii strain NCTC7865

48.79

98.413

0.48
  comE/comE1 Streptococcus gordonii str. Challis substr. CH1

48.79

98.413

0.48
  comE Streptococcus pneumoniae Rx1

46.371

98.413

0.456
  comE Streptococcus pneumoniae D39

46.371

98.413

0.456
  comE Streptococcus pneumoniae R6

46.371

98.413

0.456
  comE Streptococcus pneumoniae TIGR4

46.371

98.413

0.456
  comE Streptococcus mitis SK321

46.371

98.413

0.456
  comE Streptococcus mitis NCTC 12261

46.371

98.413

0.456
  comE Streptococcus infantis strain Atu-4

45.161

98.413

0.444
  comE/blpR Streptococcus mutans UA159

37.652

98.016

0.369

Multiple sequence alignment