Detailed information NTG1029452

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: AB4X21_RS10070
• Genome accession: NZ_CP163380
• Coordinates: 2049669..2050850 (+)
• Length: 393 a.a.
• NCBI ID: WP_151379379.1
• Uniprot ID: -
• Organism: Streptococcus sp. CP1998
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2044669..2055850

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AB4X21_RS10050 (AB4X21_10050)	comE/comE2	2046427..2047185 (-)	759	WP_151379380.1	LytTR family DNA-binding domain-containing protein	Regulator
AB4X21_RS10055 (AB4X21_10055)	-	2047182..2048522 (-)	1341	WP_270300096.1	GHKL domain-containing protein	-
AB4X21_RS10065 (AB4X21_10065)	rlmH	2048985..2049464 (-)	480	WP_369087941.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
AB4X21_RS10070 (AB4X21_10070)	htrA	2049669..2050850 (+)	1182	WP_151379379.1	S1C family serine protease	Regulator
AB4X21_RS10075 (AB4X21_10075)	spo0J	2050922..2051683 (+)	762	WP_369087942.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 393 a.a.
• Molecular weight: 41677.79 Da
• Isoelectric Point: 5.7871

>NTDB_id=1029452 AB4X21_RS10070 WP_151379379.1 2049669..2050850(+) (htrA) [Streptococcus sp. CP1998]
MKSSSNLLKKVGSIALIFVVGFLGGILGTFLTLQTSHSSTSNTESKQVHSTTVKTAYKNTTSTSEAVDKVKNAVVSVITY
SDSSNQGLFEKEENSDSQISSEGSGVIYKKEGKYAYLVTNTHVINGAKKVDILLADGNKVPGEVVGSDIYSDIAVVRISA
DKAKAVAEFGDSNQLTVGETAIAIGSPLGTDYANSVTQGIISSQGRNVKLKADNGQNISTRALQTDAAINPGNSGGPLIN
IQGQVIGITSSKISNNGQTSVEGMGFAIPANDVVNIIKQLEEKGKVVRPALGIQMMDLSNLSTSDLSQLKLPEKISGGVL
VRSTLENMPASDKLQRYDVITKIDDTDIESTADLQSALYSHQINDTIKVTFYRDGKQQTTSIKLTKSTEDLSD

Nucleotide

• Length: 1182 bp

>NTDB_id=1029452 AB4X21_RS10070 WP_151379379.1 2049669..2050850(+) (htrA) [Streptococcus sp. CP1998]
ATGAAATCTTCATCTAATTTACTGAAAAAAGTTGGAAGCATAGCCCTCATTTTTGTTGTGGGTTTTCTAGGTGGGATTCT
TGGAACCTTTTTAACCTTACAAACATCTCATTCTTCTACTTCAAATACTGAAAGTAAGCAAGTCCACTCAACCACTGTTA
AAACAGCTTATAAAAATACGACCTCAACTAGTGAAGCCGTCGATAAAGTGAAAAATGCTGTTGTTTCTGTAATTACTTAT
TCTGATTCTTCGAATCAAGGATTGTTTGAAAAAGAAGAAAACTCTGACTCACAAATTTCTAGTGAAGGTTCTGGAGTCAT
TTATAAAAAAGAAGGAAAATATGCCTACCTTGTTACCAATACCCATGTCATTAATGGTGCTAAAAAAGTAGATATTCTTT
TAGCAGATGGTAATAAAGTCCCTGGAGAAGTAGTTGGATCAGATATCTATTCTGATATTGCAGTAGTTCGCATTAGTGCG
GATAAAGCAAAGGCAGTAGCTGAATTCGGAGATTCAAACCAATTAACGGTTGGTGAGACTGCGATTGCGATCGGTAGCCC
TCTTGGAACAGATTATGCTAATTCTGTTACCCAAGGGATTATTTCCAGCCAAGGCCGCAATGTGAAATTGAAAGCCGATA
ATGGACAAAATATCTCTACACGTGCCTTACAAACAGATGCAGCCATCAACCCAGGGAATTCTGGAGGTCCATTAATCAAT
ATTCAAGGACAAGTCATTGGAATTACCTCAAGTAAAATTTCAAATAACGGACAAACTTCAGTAGAAGGAATGGGATTTGC
AATTCCTGCAAATGATGTTGTCAATATTATCAAGCAACTAGAAGAAAAAGGAAAAGTGGTTCGACCAGCTCTTGGAATCC
AAATGATGGATTTATCCAATCTTTCAACTTCTGATTTAAGCCAATTAAAACTTCCTGAAAAAATCTCTGGAGGGGTACTG
GTTCGTTCAACACTTGAAAATATGCCTGCTTCAGATAAATTGCAACGCTACGATGTCATCACAAAGATTGATGATACAGA
TATCGAGTCAACTGCAGATTTACAATCTGCCCTTTATTCTCACCAAATCAATGATACGATCAAGGTCACATTCTATCGTG
ATGGAAAACAACAAACAACTTCTATCAAGTTGACAAAATCAACTGAGGATCTAAGCGATTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (289-384)

• Trypsin-like peptidase domain (Trypsin_2) (103-248)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus gordonii str. Challis substr. CH1	68.09	100	0.69
htrA	Streptococcus mitis NCTC 12261	63.359	100	0.634
htrA	Streptococcus pneumoniae Rx1	63.359	100	0.634
htrA	Streptococcus pneumoniae D39	63.359	100	0.634
htrA	Streptococcus pneumoniae R6	63.359	100	0.634
htrA	Streptococcus pneumoniae TIGR4	63.359	100	0.634
htrA	Streptococcus mutans UA159	54.026	97.964	0.529