Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   AB4X21_RS04080 Genome accession   NZ_CP163380
Coordinates   771502..772170 (+) Length   222 a.a.
NCBI ID   WP_369088229.1    Uniprot ID   A0AB39LCT3
Organism   Streptococcus sp. CP1998     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 766502..777170
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AB4X21_RS04060 (AB4X21_04060) - 767094..767357 (-) 264 WP_270298751.1 GIY-YIG nuclease family protein -
  AB4X21_RS04065 (AB4X21_04065) - 767347..768093 (-) 747 WP_369088228.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  AB4X21_RS04070 (AB4X21_04070) - 768174..770513 (-) 2340 WP_320910852.1 cation-translocating P-type ATPase -
  AB4X21_RS04075 (AB4X21_04075) - 770689..771435 (+) 747 WP_155171508.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  AB4X21_RS04080 (AB4X21_04080) comEA/celA/cilE 771502..772170 (+) 669 WP_369088229.1 helix-hairpin-helix domain-containing protein Machinery gene
  AB4X21_RS04085 (AB4X21_04085) comEC/celB 772151..774397 (+) 2247 WP_369088230.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  AB4X21_RS04090 (AB4X21_04090) - 774473..775075 (+) 603 WP_369088231.1 DUF805 domain-containing protein -
  AB4X21_RS04095 (AB4X21_04095) holA 775099..776133 (+) 1035 WP_369088232.1 DNA polymerase III subunit delta -
  AB4X21_RS04100 (AB4X21_04100) - 776222..776824 (+) 603 Protein_756 superoxide dismutase -

Sequence

Protein


Download         Length: 222 a.a.        Molecular weight: 23923.67 Da        Isoelectric Point: 5.0097

>NTDB_id=1029427 AB4X21_RS04080 WP_369088229.1 771502..772170(+) (comEA/celA/cilE) [Streptococcus sp. CP1998]
MEDIIEKIKEYKLFLALTAIGLLLGGYFLFHRPQSSASTIPDFYQSSSSTSSKEKVQTASSKEEKTATSVSDAPEIITVD
VKGAVKQPGVYELRSDSRVHDAIHKAGGMTADANSQSVNLAQKLSDEAVIYVAKEGEDVPALGSSESPETSSAPAEKTDK
VHLNRATESELQTVSGIGQKRAQDIIAYREANGPFRSVNDLKNVSGIGEKTLEKLRDAFTVD

Nucleotide


Download         Length: 669 bp        

>NTDB_id=1029427 AB4X21_RS04080 WP_369088229.1 771502..772170(+) (comEA/celA/cilE) [Streptococcus sp. CP1998]
ATGGAGGATATCATCGAAAAAATCAAAGAATATAAGCTCTTTTTAGCTCTTACTGCTATCGGACTCTTACTTGGAGGGTA
TTTTCTTTTTCATCGACCTCAGTCAAGTGCATCCACCATACCGGATTTTTATCAGTCTTCTAGTTCAACTTCGAGCAAAG
AAAAGGTGCAGACCGCTAGTTCCAAAGAAGAAAAGACGGCGACTTCTGTGTCTGATGCACCCGAGATCATTACGGTCGAT
GTCAAAGGAGCCGTCAAACAACCAGGTGTCTATGAGTTGCGCTCAGATAGCAGAGTCCACGATGCTATTCATAAGGCGGG
TGGGATGACAGCAGATGCCAATAGCCAATCGGTCAACTTGGCGCAAAAACTCTCCGATGAAGCAGTGATCTATGTTGCTA
AAGAAGGAGAGGATGTTCCAGCACTTGGAAGTTCTGAAAGTCCTGAAACTTCGTCAGCGCCAGCAGAAAAAACAGACAAG
GTCCATTTAAATCGAGCGACCGAATCAGAGCTCCAGACAGTATCAGGCATTGGCCAGAAACGTGCCCAGGACATTATCGC
CTATCGCGAGGCAAATGGTCCTTTTCGATCAGTGAATGATCTGAAGAATGTTTCAGGAATCGGAGAGAAAACACTGGAGA
AACTAAGAGATGCTTTCACGGTGGATTAA

Domains

Predicted by InterproScan.

SLBB domain (SLBB)

(79-132)

Helix-hairpin-helix motif (HHH_3)

(158-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus mitis NCTC 12261

50.45

100

0.505
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

48.889

100

0.495
  comEA/celA/cilE Streptococcus mitis SK321

48.661

100

0.491
  comEA/celA/cilE Streptococcus pneumoniae R6

48.649

100

0.486
  comEA/celA/cilE Streptococcus pneumoniae Rx1

48.649

100

0.486
  comEA/celA/cilE Streptococcus pneumoniae D39

48.649

100

0.486
  comEA Lactococcus lactis subsp. cremoris KW2

43.103

100

0.45
  comEA Streptococcus thermophilus LMD-9

43.421

100

0.446
  comEA Staphylococcus aureus MW2

35.874

100

0.36

Multiple sequence alignment