Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC/celB   Type   Machinery gene
Locus tag   AB4X21_RS04085 Genome accession   NZ_CP163380
Coordinates   772151..774397 (+) Length   748 a.a.
NCBI ID   WP_369088230.1    Uniprot ID   A0AB39LF47
Organism   Streptococcus sp. CP1998     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 767151..779397
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AB4X21_RS04065 (AB4X21_04065) - 767347..768093 (-) 747 WP_369088228.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  AB4X21_RS04070 (AB4X21_04070) - 768174..770513 (-) 2340 WP_320910852.1 cation-translocating P-type ATPase -
  AB4X21_RS04075 (AB4X21_04075) - 770689..771435 (+) 747 WP_155171508.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  AB4X21_RS04080 (AB4X21_04080) comEA/celA/cilE 771502..772170 (+) 669 WP_369088229.1 helix-hairpin-helix domain-containing protein Machinery gene
  AB4X21_RS04085 (AB4X21_04085) comEC/celB 772151..774397 (+) 2247 WP_369088230.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  AB4X21_RS04090 (AB4X21_04090) - 774473..775075 (+) 603 WP_369088231.1 DUF805 domain-containing protein -
  AB4X21_RS04095 (AB4X21_04095) holA 775099..776133 (+) 1035 WP_369088232.1 DNA polymerase III subunit delta -
  AB4X21_RS04100 (AB4X21_04100) - 776222..776824 (+) 603 Protein_756 superoxide dismutase -
  AB4X21_RS04105 (AB4X21_04105) - 777035..778502 (+) 1468 Protein_757 helicase HerA-like domain-containing protein -

Sequence

Protein


Download         Length: 748 a.a.        Molecular weight: 85770.09 Da        Isoelectric Point: 9.1905

>NTDB_id=1029428 AB4X21_RS04085 WP_369088230.1 772151..774397(+) (comEC/celB) [Streptococcus sp. CP1998]
MLSRWIKNLPFSLIHLAFVLLWSYYSVYQPSWLSISGLVVVGILAVHHYKGERSSLLGLALATLCFAAFFVFQRLQDHPV
QAESQPPSHLRLIPDTIKINGDALSFRARNQGRTYQVFYTLKSEKEKQHWQSQTHLLELTYKGVIEEPEGQRNFRGFDYR
SYLETQGIHYQIKIEAIQSALPIQTWNVFDWLSRWRRQAIVWSKEHFPQPMNQYMTGLLFGYLDTDFEEMDQLYTSLGII
HLFALSGMQVGFFINGIRKALLRLGILQETVDIWMVPISLVYAGLTGFSVSVVRSLLQKILSQKGIRGMENMAMTLLLLM
FLMPKFLLTAGGVLSCAYAFILTLVDTSSYSGLKKILVESFWISLGILPLLTYYFSVFQPWSLPLTFLFSFLFDLVLLPG
LTVLFILSILKPLTIFNSFFLLIEECIRWISKLTSLPLVFGQPTGPALIALFLLLGILYDLRKKKNFRFLVIGMILLIFC
WTKHPLENEITMVDIGQGDSIFLRDWKGRTILIDVGGRVTFKSGDKWQERSQSANADQTLIPYLKSRGVGKIDALVLTHT
DQDHMGDMVEVAKQIPVKKVYVSPGSLTNSQFREKLKQLHSPIKVVQRGDRLPIFDHHLEVLSPDEVGDGKNDDSIVLYG
QFYQKRFLFTGDLEEAGEKKLLENDPQLQVDVLKVGHHGSKGSSSDVFLDQLHPQLALISVGKKNRYQHPHKELLDRLEE
RSISYLRTDERGAIRLIGWEHWRVETVR

Nucleotide


Download         Length: 2247 bp        

>NTDB_id=1029428 AB4X21_RS04085 WP_369088230.1 772151..774397(+) (comEC/celB) [Streptococcus sp. CP1998]
ATGCTTTCACGGTGGATTAAAAACCTTCCTTTTTCGCTTATCCATCTCGCCTTTGTACTCCTATGGTCGTATTATAGTGT
TTATCAACCATCTTGGCTTTCGATCAGCGGTCTAGTAGTAGTGGGAATTTTAGCGGTTCATCACTATAAAGGGGAGCGCT
CAAGTTTGCTAGGGCTTGCTTTAGCAACCCTTTGTTTTGCGGCCTTCTTTGTCTTTCAGCGACTACAGGATCATCCAGTA
CAAGCAGAAAGTCAGCCCCCATCCCACTTACGCCTGATTCCAGATACCATCAAGATCAATGGGGATGCCCTGTCTTTTCG
TGCTAGAAATCAGGGAAGGACCTACCAAGTCTTCTACACTTTAAAATCAGAAAAAGAAAAACAGCATTGGCAAAGTCAAA
CCCACTTGCTGGAGTTGACATATAAAGGTGTTATAGAGGAACCAGAAGGGCAGCGAAATTTTAGAGGATTTGACTATCGG
TCTTATTTGGAAACACAGGGGATTCACTATCAAATAAAAATTGAAGCGATCCAATCCGCGCTTCCTATACAGACTTGGAA
TGTTTTTGACTGGCTATCTCGATGGAGACGCCAAGCCATTGTTTGGAGTAAAGAGCACTTTCCGCAGCCGATGAACCAGT
ATATGACCGGCCTTCTTTTTGGCTATTTAGATACGGATTTTGAAGAGATGGACCAGCTTTACACGAGTTTAGGCATCATC
CATTTATTCGCCTTATCTGGGATGCAGGTTGGCTTTTTCATCAATGGGATCCGGAAAGCTCTCTTACGTCTAGGAATCTT
GCAAGAAACAGTTGATATCTGGATGGTTCCAATTTCTTTGGTCTATGCTGGCTTGACAGGTTTTTCAGTTTCAGTGGTTC
GTAGTCTCTTGCAAAAGATCCTCTCTCAAAAGGGGATCCGAGGGATGGAGAATATGGCGATGACCTTGCTGCTTTTAATG
TTTCTCATGCCCAAGTTTCTCCTGACAGCTGGAGGGGTCTTGAGTTGTGCCTATGCCTTTATTTTGACCTTGGTAGATAC
CAGTTCTTATTCAGGACTTAAAAAGATACTAGTGGAAAGTTTCTGGATTAGCCTGGGGATTTTGCCTCTTTTGACCTATT
ACTTTAGTGTCTTTCAACCCTGGTCACTCCCTTTAACCTTCCTCTTTTCTTTCTTATTTGACCTTGTTCTTCTTCCGGGT
TTAACGGTGCTATTTATCTTATCGATTCTAAAGCCCCTTACCATTTTTAACAGTTTCTTTCTTCTCATAGAGGAGTGTAT
TCGTTGGATTTCAAAGCTCACGTCGCTACCTTTGGTATTCGGTCAGCCGACGGGACCAGCTCTGATCGCTCTCTTCCTTC
TTTTAGGGATCTTGTATGATCTTCGAAAGAAAAAGAACTTTCGTTTTCTGGTAATAGGCATGATTCTACTCATCTTTTGT
TGGACCAAACATCCTTTAGAAAATGAGATCACCATGGTGGATATCGGTCAAGGAGACAGTATCTTTTTACGCGATTGGAA
AGGAAGAACCATATTAATTGATGTCGGAGGACGCGTCACTTTTAAAAGTGGAGACAAGTGGCAAGAGCGCAGTCAATCTG
CTAATGCGGATCAAACCTTGATTCCATATCTCAAGAGTCGAGGTGTTGGAAAAATCGATGCGCTGGTCTTGACTCATACA
GACCAGGACCATATGGGTGATATGGTGGAGGTCGCCAAACAAATCCCAGTTAAAAAAGTGTATGTCAGTCCAGGCAGTCT
AACCAATTCTCAATTTCGAGAGAAATTGAAACAGCTTCATAGTCCGATTAAAGTAGTCCAGAGAGGGGATCGACTTCCTA
TTTTTGATCATCATCTAGAAGTCTTATCCCCTGATGAAGTGGGGGATGGTAAAAATGATGATTCGATTGTCCTATACGGG
CAGTTCTATCAGAAACGATTTTTGTTCACGGGTGATCTAGAAGAAGCTGGAGAGAAAAAACTATTGGAAAACGATCCACA
ATTACAAGTAGATGTCTTGAAAGTAGGCCACCACGGATCTAAAGGTTCCTCTAGTGATGTGTTTTTAGACCAGTTACATC
CTCAGTTGGCCTTGATCTCTGTTGGAAAGAAAAATCGCTACCAGCATCCCCATAAAGAATTGCTCGATCGTCTAGAGGAA
CGCTCTATTTCTTATCTTCGTACCGATGAAAGAGGAGCAATTCGCTTGATTGGATGGGAGCATTGGAGGGTAGAAACGGT
CCGCTAG

Domains

Predicted by InterproScan.

Competence protein (Competence)

(218-463)

Metallo-beta-lactamase superfamily (Lactamase_B)

(496-700)

Domain of unknown function (DUF4131) (DUF4131)

(30-178)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC/celB Streptococcus mitis SK321

53.129

100

0.533
  comEC/celB Streptococcus mitis NCTC 12261

52.4

100

0.525
  comEC/celB Streptococcus pneumoniae TIGR4

52.33

100

0.525
  comEC/celB Streptococcus pneumoniae Rx1

52.064

100

0.523
  comEC/celB Streptococcus pneumoniae D39

52.064

100

0.523
  comEC/celB Streptococcus pneumoniae R6

52.064

100

0.523
  comEC Lactococcus lactis subsp. cremoris KW2

49.28

92.781

0.457

Multiple sequence alignment