Detailed information NTG1021573

Bioinformatically predicted

Overview

• Name: comE/blpR
• Type: Regulator
• Locus tag: DQM69_RS01290
• Genome accession: NZ_LS483381
• Coordinates: 235708..236457 (+)
• Length: 249 a.a.
• NCBI ID: WP_019770842.1
• Uniprot ID: -
• Organism: Streptococcus sobrinus strain NCTC10921
• Function: activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 230708..241457

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM69_RS01270 (NCTC10921_00251)	-	231122..231667 (+)	546	WP_002962460.1	cysteine hydrolase family protein	-
DQM69_RS01275 (NCTC10921_00252)	gltX	231754..233208 (+)	1455	WP_019775465.1	glutamate--tRNA ligase	-
DQM69_RS01280 (NCTC10921_00253)	pnuC	233762..234562 (+)	801	WP_002962375.1	nicotinamide riboside transporter PnuC	-
DQM69_RS01285 (NCTC10921_00254)	-	234559..235293 (+)	735	WP_019770841.1	NUDIX domain-containing protein	-
DQM69_RS01290 (NCTC10921_00255)	comE/blpR	235708..236457 (+)	750	WP_019770842.1	response regulator transcription factor	Regulator
DQM69_RS01295 (NCTC10921_00256)	-	237258..238448 (+)	1191	WP_019770844.1	argininosuccinate synthase	-
DQM69_RS01300 (NCTC10921_00257)	argH	238897..240276 (+)	1380	WP_109982386.1	argininosuccinate lyase	-

Sequence

Protein

• Length: 249 a.a.
• Molecular weight: 28722.86 Da
• Isoelectric Point: 5.2334

>NTDB_id=1021573 DQM69_RS01290 WP_019770842.1 235708..236457(+) (comE/blpR) [Streptococcus sobrinus strain NCTC10921]
MNIFILEDNLIQQTRIKTLVAEILREDGVSARQFEVFSKSQNLLDAIVEKGNHQLFLLDIEIKGEEKRGLETAADIRQID
PNAIIVFVTTHSEFAPISFKYKVSALDFIDKTAPDEQFKADLREVIAYTANNMHRSEEVDEVFTFESAQARVQLPFKDIY
YFATSPTPHKVMLITRNERLEFYGSLSEIVEVNSKLFSCHRSFLINLDNISRVDKANLLVYFENGDFCPVSRLKMKALMK
EWEARQGKT

Nucleotide

• Length: 750 bp

>NTDB_id=1021573 DQM69_RS01290 WP_019770842.1 235708..236457(+) (comE/blpR) [Streptococcus sobrinus strain NCTC10921]
ATGAATATATTTATTTTAGAGGATAATTTAATCCAGCAGACGCGGATTAAAACTCTGGTGGCAGAGATTTTGCGGGAGGA
TGGCGTGTCCGCCCGTCAGTTTGAGGTTTTTTCAAAATCGCAAAATTTATTGGATGCGATTGTTGAAAAGGGGAATCATC
AACTGTTTCTTCTGGATATTGAGATTAAGGGAGAAGAAAAGCGGGGATTGGAGACTGCAGCGGACATCCGTCAGATTGAT
CCCAATGCTATTATTGTTTTTGTGACTACCCATTCAGAATTTGCACCAATTAGCTTCAAGTATAAGGTGTCTGCCCTTGA
TTTTATTGATAAGACGGCTCCTGATGAGCAGTTCAAAGCCGATTTGCGGGAGGTCATCGCCTATACGGCCAATAATATGC
ATCGTTCTGAGGAAGTTGATGAAGTCTTTACCTTTGAGTCCGCCCAAGCGCGTGTTCAGCTCCCTTTCAAGGATATTTAC
TACTTTGCGACCTCCCCAACTCCTCACAAGGTTATGTTGATTACGAGGAATGAGCGGCTTGAGTTTTATGGTAGTCTGTC
AGAAATTGTTGAAGTTAATTCCAAACTCTTCTCCTGTCACCGTTCTTTCCTGATAAATTTGGATAATATCAGTCGTGTTG
ATAAGGCCAACTTACTGGTCTATTTTGAAAATGGAGACTTCTGTCCAGTATCGCGTTTAAAGATGAAGGCGCTTATGAAG
GAGTGGGAAGCTAGACAGGGCAAGACCTAA

Domains

Predicted by InterProScan.

• LytTr DNA-binding domain (LytTR) (152-240)

• Response regulator receiver domain (Response_reg) (3-120)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/blpR	Streptococcus mutans UA159	49.58	95.582	0.474
comE/comE1	Streptococcus equinus JB1	43.673	98.394	0.43
comE/comE2	Streptococcus gordonii strain NCTC7865	40.637	100	0.41
comE/comE1	Streptococcus gordonii str. Challis substr. CH1	40.637	100	0.41
comE/comE2	Streptococcus equinus JB1	40.741	97.59	0.398
comE	Streptococcus mitis NCTC 12261	37.052	100	0.373
comE	Streptococcus pneumoniae D39	37.052	100	0.373
comE	Streptococcus pneumoniae Rx1	37.052	100	0.373
comE	Streptococcus pneumoniae R6	37.052	100	0.373
comE	Streptococcus pneumoniae TIGR4	37.052	100	0.373
comE	Streptococcus mitis SK321	37.052	100	0.373
comE	Streptococcus infantis strain Atu-4	36.653	100	0.369