Detailed information NTG1021371

Bioinformatically predicted

Overview

• Name: comE/blpR
• Type: Regulator
• Locus tag: DQM97_RS01305
• Genome accession: NZ_LS483378
• Coordinates: 236620..237369 (+)
• Length: 249 a.a.
• NCBI ID: WP_002962370.1
• Uniprot ID: A0ABM6W475
• Organism: Streptococcus sobrinus strain NCTC12279
• Function: activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 231620..242369

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM97_RS01285 (NCTC12279_00258)	-	232035..232580 (+)	546	WP_002962460.1	cysteine hydrolase family protein	-
DQM97_RS01290 (NCTC12279_00259)	gltX	232667..234121 (+)	1455	WP_002962462.1	glutamate--tRNA ligase	-
DQM97_RS01295 (NCTC12279_00260)	pnuC	234675..235475 (+)	801	WP_002962375.1	nicotinamide riboside transporter PnuC	-
DQM97_RS01300 (NCTC12279_00261)	-	235472..236206 (+)	735	WP_002962372.1	NUDIX hydrolase	-
DQM97_RS01305 (NCTC12279_00262)	comE/blpR	236620..237369 (+)	750	WP_002962370.1	response regulator transcription factor	Regulator
DQM97_RS01310 (NCTC12279_00263)	-	238169..239359 (+)	1191	WP_002962368.1	argininosuccinate synthase	-
DQM97_RS01315 (NCTC12279_00264)	argH	239729..241177 (+)	1449	WP_019769029.1	argininosuccinate lyase	-

Sequence

Protein

• Length: 249 a.a.
• Molecular weight: 28712.82 Da
• Isoelectric Point: 5.2334

>NTDB_id=1021371 DQM97_RS01305 WP_002962370.1 236620..237369(+) (comE/blpR) [Streptococcus sobrinus strain NCTC12279]
MNIFILEDNLIQQTRIKTLVAEILREDGVSARQFEVFSKSQNLLDAIVEKGNHQLFLLDIEIKGEEKRGLETAADIRQID
SNAIIVFVTTHSEFAPISFKYKVSALDFIDKTAPDEQFKADLREVIAYTANNMHRSEEVDEVFTFESAQARVQLPFKDIY
YFATSPTPHKVMLITRNERLEFYGSLSEIVEVNSKLFSCHRSFLINLDNISRVDKANLLVYFENGDFCPVSRLKMKALMK
EWEARQGKT

Nucleotide

• Length: 750 bp

>NTDB_id=1021371 DQM97_RS01305 WP_002962370.1 236620..237369(+) (comE/blpR) [Streptococcus sobrinus strain NCTC12279]
ATGAATATATTTATTTTAGAGGATAATTTAATCCAGCAGACGCGGATTAAAACTCTGGTGGCAGAGATTTTGCGGGAGGA
TGGCGTGTCCGCCCGTCAGTTTGAGGTTTTTTCAAAATCGCAAAATTTATTGGATGCGATTGTTGAAAAGGGGAATCATC
AACTGTTTCTTCTGGATATTGAGATTAAGGGAGAAGAAAAGCGGGGATTGGAGACTGCAGCGGACATCCGTCAGATTGAT
TCTAATGCTATCATTGTTTTTGTGACTACCCATTCAGAATTTGCACCAATTAGCTTCAAGTATAAGGTGTCTGCCCTTGA
TTTTATTGATAAGACGGCTCCTGATGAGCAGTTCAAAGCCGATTTGCGGGAGGTCATCGCCTATACGGCCAATAATATGC
ATCGTTCTGAGGAAGTTGATGAAGTCTTTACCTTTGAGTCCGCCCAAGCGCGTGTTCAGCTCCCTTTCAAGGATATTTAC
TACTTTGCGACCTCCCCAACTCCTCACAAGGTTATGTTGATTACGAGGAATGAGCGGCTTGAGTTTTATGGTAGTCTGTC
AGAAATTGTTGAAGTTAATTCCAAACTCTTCTCCTGTCACCGTTCCTTCCTGATAAATTTGGATAATATCAGTCGTGTTG
ATAAGGCCAACTTACTGGTCTATTTTGAAAATGGAGACTTCTGTCCAGTATCGCGTTTAAAGATGAAGGCGCTTATGAAG
GAGTGGGAAGCTAGACAGGGCAAGACCTAA

Domains

Predicted by InterProScan.

• LytTr DNA-binding domain (LytTR) (152-240)

• Response regulator receiver domain (Response_reg) (3-120)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/blpR	Streptococcus mutans UA159	49.16	95.582	0.47
comE/comE1	Streptococcus equinus JB1	43.265	98.394	0.426
comE/comE2	Streptococcus gordonii strain NCTC7865	40.239	100	0.406
comE/comE1	Streptococcus gordonii str. Challis substr. CH1	40.239	100	0.406
comE/comE2	Streptococcus equinus JB1	40.741	97.59	0.398
comE	Streptococcus mitis NCTC 12261	36.653	100	0.369
comE	Streptococcus pneumoniae D39	36.653	100	0.369
comE	Streptococcus pneumoniae Rx1	36.653	100	0.369
comE	Streptococcus pneumoniae R6	36.653	100	0.369
comE	Streptococcus pneumoniae TIGR4	36.653	100	0.369
comE	Streptococcus mitis SK321	36.653	100	0.369
comE	Streptococcus infantis strain Atu-4	36.255	100	0.365