Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   ABZ559_RS12630 Genome accession   NZ_CP160400
Coordinates   2507291..2508028 (-) Length   245 a.a.
NCBI ID   WP_367006675.1    Uniprot ID   -
Organism   Streptococcus sp. ZY19097     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 2502291..2513028
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABZ559_RS12610 (ABZ559_12610) - 2503406..2504179 (-) 774 WP_367006667.1 hypothetical protein -
  ABZ559_RS12615 (ABZ559_12615) - 2504181..2505056 (-) 876 WP_367006668.1 ABC transporter ATP-binding protein -
  ABZ559_RS12620 (ABZ559_12620) - 2505084..2505821 (-) 738 WP_367006671.1 hypothetical protein -
  ABZ559_RS12625 (ABZ559_12625) - 2505933..2507297 (-) 1365 WP_367006673.1 GHKL domain-containing protein -
  ABZ559_RS12630 (ABZ559_12630) comE/blpR 2507291..2508028 (-) 738 WP_367006675.1 response regulator transcription factor Regulator
  ABZ559_RS12635 (ABZ559_12635) - 2508135..2508476 (+) 342 WP_277291053.1 hypothetical protein -
  ABZ559_RS12640 (ABZ559_12640) - 2508763..2509317 (+) 555 WP_367006676.1 TetR/AcrR family transcriptional regulator -
  ABZ559_RS12645 (ABZ559_12645) - 2509314..2509547 (+) 234 WP_367006677.1 hypothetical protein -
  ABZ559_RS12650 (ABZ559_12650) - 2509560..2510180 (+) 621 WP_367006678.1 hypothetical protein -
  ABZ559_RS12655 (ABZ559_12655) - 2510353..2510736 (-) 384 WP_367006679.1 hypothetical protein -
  ABZ559_RS12660 (ABZ559_12660) - 2510856..2511128 (-) 273 WP_367006681.1 hypothetical protein -
  ABZ559_RS12665 (ABZ559_12665) recO 2511249..2512007 (-) 759 WP_018375457.1 DNA repair protein RecO -

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28185.23 Da        Isoelectric Point: 5.2192

>NTDB_id=1020966 ABZ559_RS12630 WP_367006675.1 2507291..2508028(-) (comE/blpR) [Streptococcus sp. ZY19097]
MLRIFILEDDFMQQARLEQVIEEAVKTSDVAYKTLEVFGKPQQLLEAVTETGNHQLFFLDIEIRGEEKKGMEIAREIRAR
DPHAVIVFVTTHSEFMPLTYKYRVSALDFIDKGLDEPAFKEAVADVLQHAYSHISQTVSDDAFVFKSEFSQIQVPFSDIL
YFETSSTPHKVVLTTKSGHTEFYGKVSDIAKMDERLYQSHRAYVVNPANILRVDAVERMVYFEQEESCLVSRMKLKGLLE
RVGKC

Nucleotide


Download         Length: 738 bp        

>NTDB_id=1020966 ABZ559_RS12630 WP_367006675.1 2507291..2508028(-) (comE/blpR) [Streptococcus sp. ZY19097]
ATGTTACGGATTTTTATCTTGGAAGATGATTTTATGCAACAAGCTAGGTTGGAGCAGGTGATTGAGGAAGCTGTAAAAAC
GAGTGACGTTGCCTACAAGACCTTAGAAGTGTTTGGTAAACCTCAGCAGTTACTTGAGGCTGTAACAGAGACTGGAAACC
ATCAACTCTTTTTCCTAGATATTGAGATTAGAGGTGAGGAGAAGAAAGGGATGGAGATTGCACGGGAGATAAGGGCGCGT
GATCCGCATGCTGTGATTGTTTTTGTAACGACGCATTCGGAATTTATGCCTTTGACCTATAAATACCGTGTGTCAGCTCT
TGATTTTATTGATAAGGGGTTGGATGAGCCTGCCTTTAAGGAAGCGGTGGCAGATGTTCTCCAACATGCTTATAGTCATA
TCAGTCAGACTGTGAGTGATGATGCTTTTGTTTTCAAGAGTGAGTTTTCTCAGATTCAGGTGCCGTTTTCAGATATTTTG
TATTTTGAAACCTCTTCAACGCCTCATAAGGTTGTCTTGACAACCAAGTCAGGTCATACAGAGTTTTATGGCAAGGTATC
AGATATTGCTAAAATGGATGAACGTTTGTACCAGAGCCATCGGGCTTATGTGGTCAATCCTGCTAATATTCTTCGTGTGG
ATGCTGTGGAGCGGATGGTTTATTTTGAACAGGAGGAATCTTGCTTGGTCTCTCGAATGAAACTGAAAGGTTTGCTAGAG
AGGGTTGGTAAATGCTAG

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(152-241)

Response regulator receiver domain (Response_reg)

(4-123)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

55.649

97.551

0.543
  comE/comE1 Streptococcus equinus JB1

45.607

97.551

0.445
  comE/comE2 Streptococcus equinus JB1

40.336

97.143

0.392
  comE/comE2 Streptococcus gordonii strain NCTC7865

38.272

99.184

0.38
  comE/comE1 Streptococcus gordonii str. Challis substr. CH1

38.272

99.184

0.38
  comE Streptococcus infantis strain Atu-4

36.905

100

0.38
  comE Streptococcus mitis SK321

37.449

99.184

0.371
  comE Streptococcus pneumoniae Rx1

37.449

99.184

0.371
  comE Streptococcus pneumoniae D39

37.449

99.184

0.371
  comE Streptococcus pneumoniae R6

37.449

99.184

0.371
  comE Streptococcus pneumoniae TIGR4

37.449

99.184

0.371
  comE Streptococcus mitis NCTC 12261

37.449

99.184

0.371

Multiple sequence alignment