Detailed information NTG1006432

Bioinformatically predicted

Overview

• Name: comE/blpR
• Type: Regulator
• Locus tag: FQT45_RS09610
• Genome accession: NZ_LR595858
• Coordinates: 1950312..1951049 (-)
• Length: 245 a.a.
• NCBI ID: WP_077322586.1
• Uniprot ID: -
• Organism: Streptococcus pseudoporcinus strain NCTC10228
• Function: activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1945312..1956049

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FQT45_RS09585	-	1945926..1946078 (-)	153	Protein_1842	toprim domain-containing protein	-
FQT45_RS09595 (NCTC10228_01979)	jag	1947337..1948296 (-)	960	WP_077322583.1	RNA-binding cell elongation regulator Jag/EloR	-
FQT45_RS09600 (NCTC10228_01980)	-	1948312..1949124 (-)	813	WP_077322584.1	YidC/Oxa1 family membrane protein insertase	-
FQT45_RS09605 (NCTC10228_01981)	rnpA	1949108..1949467 (-)	360	WP_077322585.1	ribonuclease P protein component	-
FQT45_RS09610 (NCTC10228_01982)	comE/blpR	1950312..1951049 (-)	738	WP_077322586.1	response regulator transcription factor	Regulator
FQT45_RS09615 (NCTC10228_01983)	-	1951051..1952358 (-)	1308	WP_077322587.1	histidine kinase	-
FQT45_RS09620 (NCTC10228_01984)	-	1952359..1953705 (-)	1347	WP_077322588.1	GHKL domain-containing protein	-
FQT45_RS09625 (NCTC10228_01985)	gltX	1954085..1955530 (-)	1446	WP_077322589.1	glutamate--tRNA ligase	-

Sequence

Protein

• Length: 245 a.a.
• Molecular weight: 28803.10 Da
• Isoelectric Point: 5.2197

>NTDB_id=1006432 FQT45_RS09610 WP_077322586.1 1950312..1951049(-) (comE/blpR) [Streptococcus pseudoporcinus strain NCTC10228]
MNIFILEDDYIQQGRIESVIEEILKEQKIAKSYMEVFSNPQKLLDSIHERGEHQLFFLDIDIKGETKRGLELAAEIRMLD
SNAVIVFVTTHSEFAPISFKYKVSALDFIDKAVDNAQFKEQIQECILYTRQMMSNHETEEVFLFETPQTRLRLPYKDILY
FATSTTPHKVCLWTQTERLEFYGNLAELQEVAPKLFLCHRSFLVNLENVVRIDKSHQLVYFENGDSCLVSRLKIKHLIEK
WESLN

Nucleotide

• Length: 738 bp

>NTDB_id=1006432 FQT45_RS09610 WP_077322586.1 1950312..1951049(-) (comE/blpR) [Streptococcus pseudoporcinus strain NCTC10228]
ATGAATATTTTTATATTAGAAGACGACTATATCCAACAGGGCCGGATAGAGTCTGTCATTGAAGAGATTTTAAAAGAGCA
GAAGATCGCGAAATCTTATATGGAGGTTTTTTCTAATCCACAAAAACTCCTAGATAGTATTCATGAACGTGGAGAGCATC
AACTTTTTTTCTTAGATATTGATATCAAAGGGGAAACAAAAAGGGGATTAGAATTAGCAGCGGAGATTCGGATGTTAGAT
TCTAATGCTGTTATTGTGTTCGTTACGACCCACTCTGAATTTGCACCTATTTCATTCAAATATAAGGTTTCAGCTCTTGA
TTTTATTGATAAAGCTGTTGACAATGCCCAATTTAAAGAACAAATTCAAGAATGTATCCTCTATACAAGACAGATGATGT
CAAACCATGAGACAGAAGAAGTATTTTTGTTTGAAACCCCTCAAACTCGTCTTCGGTTACCCTATAAAGATATTTTATAT
TTTGCCACCTCGACAACTCCCCATAAGGTCTGCCTTTGGACTCAGACAGAACGTTTAGAATTTTATGGTAATTTAGCAGA
ACTTCAAGAAGTTGCCCCCAAACTATTTCTTTGTCATCGTTCATTTTTAGTGAATTTGGAAAATGTAGTGCGAATAGACA
AATCTCATCAATTGGTCTATTTTGAAAATGGGGATTCCTGCCTAGTTTCGCGTTTGAAAATAAAGCATTTAATTGAAAAA
TGGGAATCACTCAACTAA

Domains

Predicted by InterProScan.

• LytTr DNA-binding domain (LytTR) (151-241)

• Response regulator receiver domain (Response_reg) (3-122)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/blpR	Streptococcus mutans UA159	48.739	97.143	0.473
comE/comE1	Streptococcus equinus JB1	44.118	97.143	0.429
comE/comE2	Streptococcus gordonii strain NCTC7865	40.8	100	0.416
comE/comE1	Streptococcus gordonii str. Challis substr. CH1	40.8	100	0.416
comE/comE2	Streptococcus equinus JB1	41.393	99.592	0.412
comE	Streptococcus infantis strain Atu-4	38.589	98.367	0.38
comE	Streptococcus mitis NCTC 12261	38.174	98.367	0.376
comE	Streptococcus pneumoniae Rx1	38.174	98.367	0.376
comE	Streptococcus pneumoniae D39	38.174	98.367	0.376
comE	Streptococcus pneumoniae R6	38.174	98.367	0.376
comE	Streptococcus pneumoniae TIGR4	38.174	98.367	0.376
comE	Streptococcus mitis SK321	38.174	98.367	0.376