Detailed information NTG1003790

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: E0F32_RS10345
• Genome accession: NZ_LR216050
• Coordinates: 1891954..1892394 (-)
• Length: 146 a.a.
• NCBI ID: WP_001206582.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain GPSC10 substr. ST2013 isolate GPS_US_PATH396-sc-2296505
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1886954..1897394

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
E0F32_RS10315 (SAMEA3431333_01940)	-	1887263..1888138 (+)	876	WP_000669493.1	substrate-binding domain-containing protein	-
E0F32_RS10320 (SAMEA3431333_01941)	pstC	1888256..1889119 (+)	864	WP_000165892.1	phosphate ABC transporter permease subunit PstC	-
E0F32_RS10325 (SAMEA3431333_01942)	pstA	1889112..1889927 (+)	816	WP_000049768.1	phosphate ABC transporter permease PstA	-
E0F32_RS10330 (SAMEA3431333_01943)	pstB	1889929..1890681 (+)	753	WP_000536449.1	phosphate ABC transporter ATP-binding protein PstB	-
E0F32_RS10335 (SAMEA3431333_01944)	phoU	1890696..1891346 (+)	651	WP_001245781.1	phosphate signaling complex protein PhoU	-
E0F32_RS10340 (SAMEA3431333_01945)	-	1891387..1891839 (+)	453	Protein_1925	transposase	-
E0F32_RS10345 (SAMEA3431333_01946)	comR	1891954..1892394 (-)	441	WP_001206582.1	helix-turn-helix domain-containing protein	Regulator
E0F32_RS10350 (SAMEA3431333_01947)	-	1892606..1893622 (+)	1017	WP_000415103.1	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase	-
E0F32_RS10355 (SAMEA3431333_01948)	galU	1893644..1894543 (+)	900	WP_024477964.1	UTP--glucose-1-phosphate uridylyltransferase GalU	-
E0F32_RS10360 (SAMEA3431333_01949)	-	1894610..1895287 (-)	678	WP_000658498.1	rhomboid family intramembrane serine protease	-
E0F32_RS10365 (SAMEA3431333_01950)	-	1895271..1895810 (-)	540	WP_024477965.1	5-formyltetrahydrofolate cyclo-ligase	-
E0F32_RS10370 (SAMEA3431333_01951)	-	1895822..1896952 (-)	1131	WP_000885066.1	N-acetyldiaminopimelate deacetylase	-

Sequence

Protein

• Length: 146 a.a.
• Molecular weight: 17758.49 Da
• Isoelectric Point: 4.8659

>NTDB_id=1003790 E0F32_RS10345 WP_001206582.1 1891954..1892394(-) (comR) [Streptococcus pneumoniae strain GPSC10 substr. ST2013 isolate GPS_US_PATH396-sc-2296505]
MREFGEKIKRLRLAKKISRSEFCGDESELSIRQLIRIENGESRPILTKLKYIAERLEVEDYKLMPSYIELDKEYLELKYF
LMRTPTYEDETIAQKKESVFDKIFEEYYDRLPEEERFIIPNYSYLALTNYTVQKLPEKLVEILSFW

Nucleotide

• Length: 441 bp

>NTDB_id=1003790 E0F32_RS10345 WP_001206582.1 1891954..1892394(-) (comR) [Streptococcus pneumoniae strain GPSC10 substr. ST2013 isolate GPS_US_PATH396-sc-2296505]
TTGCGAGAGTTTGGCGAAAAAATTAAAAGATTACGTTTGGCTAAAAAAATCAGTCGTTCAGAATTTTGTGGTGATGAGTC
TGAATTAAGTATCCGTCAATTAATTAGAATTGAAAATGGAGAATCCAGACCAATACTAACAAAGTTAAAATATATTGCTG
AACGTTTGGAGGTTGAAGATTACAAGTTGATGCCAAGTTATATAGAGTTGGATAAGGAATACCTAGAATTGAAGTATTTC
TTGATGAGGACTCCTACATACGAAGATGAAACTATCGCCCAAAAGAAAGAGAGTGTTTTTGATAAGATTTTTGAAGAGTA
TTATGATAGGCTACCTGAGGAAGAAAGATTTATCATCCCAAATTATTCATATCTGGCACTAACGAACTACACAGTTCAAA
AATTACCAGAAAAGCTAGTTGAAATACTGTCCTTCTGGTGA

Domains

Predicted by InterProScan.

• ComR tetratricopeptide (ComR_TPR) (72-119)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus pyogenes MGAS8232	55	82.192	0.452
comR	Streptococcus pyogenes MGAS315	53.333	82.192	0.438
comR	Streptococcus mutans UA159	51.667	82.192	0.425
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	53.636	75.342	0.404
comR	Streptococcus suis P1/7	46.61	80.822	0.377
comR	Streptococcus suis 05ZYH33	46.61	80.822	0.377
comR	Streptococcus suis D9	45.763	80.822	0.37
comR/comR1	Streptococcus sobrinus strain NIDR 6715-7	46.491	78.082	0.363