Detailed information of T6SS
Note: only experimentally validated proteins are displayed in the graph.
Summary
| T6SS ID | T6SS01275  |
| T6SS type | Type i4b |
| Strain | Acinetobacter baumannii DSM 30011 |
| Replicon (RefSeq) | chromosome (NZ_JJOC02000004) |
| Location | 536657..556068 |
| Function | anti-bacterial; anti-eukaryotic |
| Comment | The A. baumannii DSM30011 T6SS is required for virulence and out-competing E. coli in vivo. |
| References | [1] Repizo GD et al (2015) Differential Role of the T6SS in Acinetobacter baumannii Virulence. PLoS One. 10(9):e0138265. [PudMed:26401654] |
Experimental investigation has been performed.T6SS components and genome coordinates
| Component | TagF | TssA | TssB | TssC | TssD | TssE | TssF | TssH | TssK | TssL | TssM |
| Number | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 1 |
| Component ID | Component | Locus tag (Gene) | Coordinate | Strand | Size (bp) | NCBI ID | Product |
|---|---|---|---|---|---|---|---|
| DSM30011_RS11500 | 531731..532909 | - | 1179 | 1129439365 | cyanate transporter | ||
| DSM30011_RS11505 | 532909..533391 | - | 483 | 1129439366 | nucleoside deaminase | ||
| DSM30011_RS11510 | 533407..534075 | - | 669 | 447154950 | ankyrin repeat domain-containing protein | ||
| DSM30011_RS11515 | 534227..535078 | + | 852 | 446382329 | LysR family transcriptional regulator | ||
| DSM30011_RS11520 | 535081..536034 | - | 954 | 1129439367 | M15 family metallopeptidase | ||
| DSM30011_RS11525 | 536042..536644 | - | 603 | 1129439368 | hypothetical protein | ||
| T6CP015846 | TssL | DSM30011_RS11530 (icmH) | 536657..537463 | - | 807 | 446005774 | type IVB secretion system protein IcmH/DotU |
| T6CP015847 | TssK | DSM30011_RS11535 (tssK) | 537481..538845 | - | 1365 | 446393589 | type VI secretion system baseplate subunit TssK |
| T6CP015848 | TssA | DSM30011_RS11540 (tssA) | 538862..539956 | - | 1095 | 445942860 | type VI secretion system protein TssA |
| T6CP015849 | TssH | DSM30011_RS11545 (tssH) | 539980..542661 | - | 2682 | 1332932850 | type VI secretion system ATPase TssH |
| DSM30011_RS11550 | 542881..543144 | - | 264 | 446090256 | PAAR domain-containing protein | ||
| DSM30011_RS11555 | 543161..543928 | - | 768 | 1129439370 | OmpA family protein | ||
| T6CP015850 | TagF | DSM30011_RS11560 (tagF) | 543931..544890 | - | 960 | 446479387 | type VI secretion system-associated protein TagF |
| T6CP015851 | TssM | DSM30011_RS11565 (tssM) | 544928..548752 | - | 3825 | 446479065 | type VI secretion system membrane subunit TssM |
| DSM30011_RS11570 | 548783..550195 | - | 1413 | 446514541 | hypothetical protein | ||
| T6CP015852 | TssK | DSM30011_RS11575 (tssG) | 550192..551190 | - | 999 | 447113133 | type VI secretion system baseplate subunit TssG |
| T6CP015853 | TssF | DSM30011_RS11580 (tssF) | 551154..552965 | - | 1812 | 1047309619 | type VI secretion system baseplate subunit TssF |
| T6CP015854 | TssE | DSM30011_RS11585 (tssE) | 552982..553458 | - | 477 | 446969775 | type VI secretion system baseplate subunit TssE |
| T6CP015855 | TssD | DSM30011_RS11590 | 553538..554041 | - | 504 | 446575849 | type VI secretion system tube protein Hcp |
| T6CP015856 | TssC | DSM30011_RS11595 (tssC) | 554091..555572 | - | 1482 | 446989267 | type VI secretion system contractile sheath large subunit |
| T6CP015857 | TssB | DSM30011_RS11600 (tssB) | 555565..556068 | - | 504 | 447041786 | type VI secretion system contractile sheath small subunit |
| DSM30011_RS11605 | 556085..556774 | - | 690 | 446792448 | hypothetical protein | ||
| DSM30011_RS11610 | 557517..557714 | + | 198 | 446900370 | hypothetical protein | ||
| DSM30011_RS11615 | 557749..558453 | + | 705 | 545155703 | SUMF1/EgtB/PvdO family nonheme iron enzyme | ||
| DSM30011_RS11620 | 558709..559614 | - | 906 | 1129439371 | sel1 repeat family protein | ||
| DSM30011_RS11625 | 559626..559919 | - | 294 | 487935666 | hypothetical protein | ||
| DSM30011_RS11630 | 559933..560409 | - | 477 | 1129439372 | hypothetical protein |
Genes in the 5-Kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any.
Download FASTA format files
Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
Experimental investigation has been performed.
Bioinformatics investigation has been performed.| Regulator ID | Locus tag (Gene) | Regulator type | Regulatory pathway | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Target (Regulation) |
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Experimental investigation has been performed. Bioinformatics investigation has been performed.| Effector ID | Locus tag (Gene) | Classification | Cognate immunity protein | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
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Experimental investigation has been performed. Bioinformatics investigation has been performed.| Immunity protein ID | Locus tag (Gene) | Cognate effector | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
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Experimental investigation has been performed.| Accessory protein ID | Locus tag (Gene) | Type | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Related structure protein | Related effector |
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