Detailed information of T6SS
Note: only experimentally validated proteins are displayed in the graph.
Summary
| T6SS ID | T6SS00930  |
| T6SS type | Type i1 |
| Strain | Escherichia coli SEPT362 |
| Replicon (RefSeq) | chromosome (NZ_AOGL01000004) |
| Location | 11200..34631 |
| Function | anti-eukaryotic; adherence |
| Comment | Virulence in chick; adhesion to and actin rearrangement in cultured epithelial cells. |
| References | [1] de Pace F et al (2010) The type VI secretion system plays a role in type 1 fimbria expression and pathogenesis of an avian pathogenic Escherichia coli strain. Infect Immun. 78(12):4990-8. [PudMed:20855516] [2] de Pace F et al (2011) Characterization of IcmF of the type VI secretion system in an avian pathogenic Escherichia coli (APEC) strain. Microbiology. 157(Pt 10):2954-62. [PudMed:21778203] |
Experimental investigation has been performed.T6SS components and genome coordinates
| Component | TssA | TssB | TssC | TssD | TssE | TssF | TssG | TssH | TssI | TssJ | TssK | TssL | TssM |
| Number | 2 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
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Component ID | Component | Locus tag (Gene) | Coordinate | Strand | Size (bp) | NCBI ID | Product |
|---|---|---|---|---|---|---|---|
| A364_RS23170 (rnhA) | 6751..7218 | - | 468 | 446840627 | ribonuclease HI | ||
| A364_RS23165 (dnaQ) | 7283..8014 | + | 732 | 485738897 | DNA polymerase III subunit epsilon | ||
| A364_RS23155 | 8552..9352 | + | 801 | 447008880 | hypothetical protein | ||
| A364_RS31070 | 9478..9687 | - | 210 | 485792222 | hypothetical protein | ||
| A364_RS23150 | 9831..10280 | - | 450 | 585328819 | DUF1311 domain-containing protein | ||
| A364_RS0124945 | 10283..11179 | - | 897 | 445924848 | hypothetical protein | ||
| T6CP016042 | TssD | A364_RS23145 | 11200..11679 | - | 480 | 447207703 | Hcp family type VI secretion system effector |
| T6CP016043 | TssA | A364_RS23140 | 11706..13055 | - | 1350 | 447010491 | type VI secretion system ImpA and VasL domain-containing protein |
| T6CP016044 | TssM | A364_RS23135 (tssM) | 13066..16500 | - | 3435 | 1511023396 | type VI secretion system membrane subunit TssM |
| T6CP016045 | TssA | A364_RS23130 (tssA) | 16609..18021 | - | 1413 | 487471235 | type VI secretion system protein TssA |
Genes in the 5-Kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any.
Download FASTA format files
Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
Experimental investigation has been performed.
Bioinformatics investigation has been performed.
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Regulator ID | Locus tag (Gene) | Regulator type | Regulatory pathway | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Target (Regulation) |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
Experimental investigation has been performed. Bioinformatics investigation has been performed.
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Effector ID | Locus tag (Gene) | Classification | Cognate immunity protein | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
|---|---|---|---|---|---|---|---|
| EFF01440 | A364_RS23060 | - | - | Escherichia coli SEPT362 | chromosome (NZ_AOGL01000004) | 31762..32280 (+) | 447065702 |
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Experimental investigation has been performed. Bioinformatics investigation has been performed.
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Immunity protein ID | Locus tag (Gene) | Cognate effector | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
|---|---|---|---|---|---|---|
| No matching records found | ||||||
Experimental investigation has been performed.
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Accessory protein ID | Locus tag (Gene) | Type | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Related structure protein | Related effector |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||