Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   ABD410_RS00655 Genome accession   NZ_CP155740
Coordinates   101656..102594 (+) Length   312 a.a.
NCBI ID   WP_023612548.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain 1851/03     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 96656..107594
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABD410_RS00645 (ABD410_00635) rpoC 97405..101046 (+) 3642 WP_023612544.1 DNA-directed RNA polymerase subunit beta' -
  ABD410_RS00650 (ABD410_00640) - 101198..101563 (+) 366 WP_002986560.1 DUF1033 family protein -
  ABD410_RS00655 (ABD410_00645) comYA 101656..102594 (+) 939 WP_023612548.1 competence type IV pilus ATPase ComGA Machinery gene
  ABD410_RS00660 (ABD410_00650) comYB 102530..103564 (+) 1035 WP_229363300.1 competence type IV pilus assembly protein ComGB Machinery gene
  ABD410_RS00665 (ABD410_00655) comYC 103566..103892 (+) 327 WP_032465607.1 competence type IV pilus major pilin ComGC Machinery gene
  ABD410_RS00670 (ABD410_00660) comGD 103867..104295 (+) 429 WP_002986548.1 competence type IV pilus minor pilin ComGD -
  ABD410_RS00675 (ABD410_00665) comGE 104252..104536 (+) 285 WP_002987779.1 competence type IV pilus minor pilin ComGE -
  ABD410_RS00680 (ABD410_00670) comYF 104529..104963 (+) 435 WP_023612536.1 competence type IV pilus minor pilin ComGF Machinery gene
  ABD410_RS00685 (ABD410_00675) comGG 104947..105273 (+) 327 WP_002992739.1 competence type IV pilus minor pilin ComGG -
  ABD410_RS00690 (ABD410_00680) comYH 105371..106324 (+) 954 WP_002987790.1 class I SAM-dependent methyltransferase Machinery gene
  ABD410_RS00695 (ABD410_00685) - 106383..107579 (+) 1197 WP_023612537.1 acetate kinase -

Sequence

Protein


Download         Length: 312 a.a.        Molecular weight: 35045.27 Da        Isoelectric Point: 8.5799

>NTDB_id=999173 ABD410_RS00655 WP_023612548.1 101656..102594(+) (comYA) [Streptococcus pyogenes strain 1851/03]
MVQALAKAILAKAEQVQAQDIYILPRADQYDLFLRIGDERRLVDVYQSDRMAPLVSHFKFVAGMIVGEKRRCQVGSCDYK
LSKDKQLSLRLSSVGDYRGQESLVIRLLHHQNKSVHYWFDGLTKVANQVGGRGLYLFAGPVGSGKTTLMYQLISNYHQEA
QVISIEDPVEIKNHQILQLQVNDDIGMTYDNLIKLSLRHRPDILVIGEIRDSQTARAVIRASLTGAMVFSTVHAKSISGV
YARLLELGVTKAELSNCLALIAYQRLLNGGALIDSTQNEFEYYSSSNWNQQIDQLLEAGHLNPKQAKLEKII

Nucleotide


Download         Length: 939 bp        

>NTDB_id=999173 ABD410_RS00655 WP_023612548.1 101656..102594(+) (comYA) [Streptococcus pyogenes strain 1851/03]
ATGGTACAAGCATTAGCAAAAGCTATTCTAGCAAAAGCTGAACAGGTTCAGGCACAAGATATTTATATTTTGCCAAGAGC
AGATCAATATGATCTTTTTTTACGAATAGGAGATGAAAGGAGATTAGTTGATGTTTATCAGAGCGATCGGATGGCTCCTC
TTGTTAGTCACTTTAAATTCGTTGCAGGAATGATAGTTGGTGAAAAGAGACGTTGTCAGGTGGGTTCATGTGATTATAAG
CTCAGTAAAGATAAGCAGTTATCTTTGCGCTTATCTAGCGTGGGTGATTATCGCGGGCAAGAAAGCTTAGTGATTCGTCT
GCTTCATCATCAAAATAAAAGTGTACATTATTGGTTTGATGGATTGACAAAAGTAGCCAATCAGGTTGGCGGTAGAGGGT
TGTATTTATTTGCAGGACCAGTTGGGTCTGGGAAGACAACCTTGATGTACCAGCTGATTTCGAATTATCATCAAGAAGCA
CAGGTTATTAGTATAGAAGATCCTGTAGAAATTAAAAATCACCAGATTTTACAATTACAAGTGAATGATGATATTGGTAT
GACTTATGACAATTTGATCAAACTGTCTTTACGCCATCGACCAGATATTTTAGTTATTGGTGAGATTCGAGATAGTCAAA
CAGCAAGAGCCGTTATTAGGGCTAGTCTAACAGGTGCCATGGTTTTTTCAACGGTTCACGCTAAAAGTATCTCGGGTGTT
TATGCAAGATTGTTAGAACTTGGTGTAACGAAAGCAGAACTGTCTAATTGCTTAGCATTAATTGCTTACCAAAGGTTACT
TAATGGAGGAGCATTGATTGACTCTACTCAAAACGAATTTGAATATTATTCCTCATCGAACTGGAATCAACAAATTGATC
AGCTTCTTGAGGCAGGACATCTCAATCCCAAGCAAGCTAAGCTTGAAAAAATTATCTAG

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA159

61.415

99.679

0.612
  comYA Streptococcus mutans UA140

61.415

99.679

0.612
  comYA Streptococcus gordonii str. Challis substr. CH1

60.45

99.679

0.603
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

60.323

99.359

0.599
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

59.164

99.679

0.59
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

58.521

99.679

0.583
  comGA/cglA/cilD Streptococcus pneumoniae D39

58.521

99.679

0.583
  comGA/cglA/cilD Streptococcus pneumoniae R6

58.521

99.679

0.583
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

58.521

99.679

0.583
  comGA Lactococcus lactis subsp. cremoris KW2

50.482

99.679

0.503
  comGA Latilactobacillus sakei subsp. sakei 23K

39.655

92.949

0.369

Multiple sequence alignment