Detailed information NTG0999176

Bioinformatically predicted

Overview

• Name: comYF
• Type: Machinery gene
• Locus tag: ABD410_RS00680
• Genome accession: NZ_CP155740
• Coordinates: 104529..104963 (+)
• Length: 144 a.a.
• NCBI ID: WP_023612536.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain 1851/03
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 99529..109963

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ABD410_RS00650 (ABD410_00640)	-	101198..101563 (+)	366	WP_002986560.1	DUF1033 family protein	-
ABD410_RS00655 (ABD410_00645)	comYA	101656..102594 (+)	939	WP_023612548.1	competence type IV pilus ATPase ComGA	Machinery gene
ABD410_RS00660 (ABD410_00650)	comYB	102530..103564 (+)	1035	WP_229363300.1	competence type IV pilus assembly protein ComGB	Machinery gene
ABD410_RS00665 (ABD410_00655)	comYC	103566..103892 (+)	327	WP_032465607.1	competence type IV pilus major pilin ComGC	Machinery gene
ABD410_RS00670 (ABD410_00660)	comGD	103867..104295 (+)	429	WP_002986548.1	competence type IV pilus minor pilin ComGD	-
ABD410_RS00675 (ABD410_00665)	comGE	104252..104536 (+)	285	WP_002987779.1	competence type IV pilus minor pilin ComGE	-
ABD410_RS00680 (ABD410_00670)	comYF	104529..104963 (+)	435	WP_023612536.1	competence type IV pilus minor pilin ComGF	Machinery gene
ABD410_RS00685 (ABD410_00675)	comGG	104947..105273 (+)	327	WP_002992739.1	competence type IV pilus minor pilin ComGG	-
ABD410_RS00690 (ABD410_00680)	comYH	105371..106324 (+)	954	WP_002987790.1	class I SAM-dependent methyltransferase	Machinery gene
ABD410_RS00695 (ABD410_00685)	-	106383..107579 (+)	1197	WP_023612537.1	acetate kinase	-
ABD410_RS00700 (ABD410_00690)	-	107766..108074 (+)	309	WP_032465606.1	hypothetical protein	-
ABD410_RS00705 (ABD410_00695)	proC	108157..108927 (-)	771	WP_002986527.1	pyrroline-5-carboxylate reductase	-

Sequence

Protein

• Length: 144 a.a.
• Molecular weight: 16688.29 Da
• Isoelectric Point: 10.2526

>NTDB_id=999176 ABD410_RS00680 WP_023612536.1 104529..104963(+) (comYF) [Streptococcus pyogenes strain 1851/03]
MSKQLSNIKAFTFLEALIALLVISGSLLVYQGLTRTLLKHSHYLARHDQDNWLLFSHQLREELSGARFYKVADNKLYVEK
GKKVLAFGQFKSHDFRKSASNGKGYQPMLFGISRSHIHIEQSQICITLKWKSGLERTFYYAFQD

Nucleotide

• Length: 435 bp

>NTDB_id=999176 ABD410_RS00680 WP_023612536.1 104529..104963(+) (comYF) [Streptococcus pyogenes strain 1851/03]
TTGAGTAAACAATTAAGTAACATAAAAGCTTTTACCTTTCTAGAGGCGTTAATAGCCTTACTCGTGATCTCAGGGTCTTT
ATTGGTTTATCAAGGTTTGACCCGAACCCTCCTTAAACATAGCCATTATCTAGCCCGTCATGATCAAGATAATTGGCTCT
TATTTTCTCATCAATTGCGAGAGGAGTTAAGTGGAGCAAGATTTTACAAAGTAGCTGATAATAAACTATACGTTGAAAAA
GGAAAGAAAGTACTAGCTTTTGGCCAATTTAAAAGTCATGATTTTCGAAAATCAGCTAGTAATGGAAAAGGGTATCAACC
CATGTTATTTGGAATATCACGTAGTCATATTCACATAGAGCAGTCACAGATTTGCATTACTTTAAAGTGGAAAAGTGGGT
TAGAAAGGACTTTTTATTATGCCTTTCAAGACTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (41-135)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYF	Streptococcus mutans UA140	50.36	96.528	0.486
comYF	Streptococcus mutans UA159	49.64	96.528	0.479
comGF	Lactococcus lactis subsp. cremoris KW2	46.715	95.139	0.444
comGF/cglF	Streptococcus mitis NCTC 12261	43.284	93.056	0.403
comGF/cglF	Streptococcus pneumoniae Rx1	42.105	92.361	0.389
comGF/cglF	Streptococcus pneumoniae D39	42.105	92.361	0.389
comGF/cglF	Streptococcus pneumoniae R6	42.105	92.361	0.389
comGF/cglF	Streptococcus pneumoniae TIGR4	42.105	92.361	0.389
comGF/cglF	Streptococcus mitis SK321	41.353	92.361	0.382