Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYC   Type   Machinery gene
Locus tag   ABD408_RS00605 Genome accession   NZ_CP155735
Coordinates   97565..97891 (+) Length   108 a.a.
NCBI ID   WP_032465607.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain 4958/15     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 92565..102891
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABD408_RS00590 (ABD408_00580) - 95197..95562 (+) 366 WP_002986560.1 DUF1033 family protein -
  ABD408_RS00595 (ABD408_00585) comYA 95655..96593 (+) 939 WP_023612548.1 competence type IV pilus ATPase ComGA Machinery gene
  ABD408_RS00600 (ABD408_00590) comYB 96529..97563 (+) 1035 WP_229363300.1 competence type IV pilus assembly protein ComGB Machinery gene
  ABD408_RS00605 (ABD408_00595) comYC 97565..97891 (+) 327 WP_032465607.1 competence type IV pilus major pilin ComGC Machinery gene
  ABD408_RS00610 (ABD408_00600) comGD 97866..98294 (+) 429 WP_002986548.1 competence type IV pilus minor pilin ComGD -
  ABD408_RS00615 (ABD408_00605) comGE 98251..98535 (+) 285 WP_002987779.1 competence type IV pilus minor pilin ComGE -
  ABD408_RS00620 (ABD408_00610) comYF 98528..98962 (+) 435 WP_023612536.1 competence type IV pilus minor pilin ComGF Machinery gene
  ABD408_RS00625 (ABD408_00615) comGG 98946..99272 (+) 327 WP_002992739.1 competence type IV pilus minor pilin ComGG -
  ABD408_RS00630 (ABD408_00620) comYH 99370..100323 (+) 954 WP_002987790.1 class I SAM-dependent methyltransferase Machinery gene
  ABD408_RS00635 (ABD408_00625) - 100382..101578 (+) 1197 WP_023612537.1 acetate kinase -
  ABD408_RS00640 (ABD408_00630) - 101765..102073 (+) 309 WP_032465606.1 hypothetical protein -

Sequence

Protein


Download         Length: 108 a.a.        Molecular weight: 12375.38 Da        Isoelectric Point: 10.0732

>NTDB_id=998885 ABD408_RS00605 WP_032465607.1 97565..97891(+) (comYC) [Streptococcus pyogenes strain 4958/15]
MINQWNNLRHKKLKGFTLLEMLLVILVISVLMLLFVPNLSKQKDRVTETGNAAVVKLVENQAELYELSQGSKPSLSQLKA
DGSITEKQEKAYQDYYNKHKNEKARLSN

Nucleotide


Download         Length: 327 bp        

>NTDB_id=998885 ABD408_RS00605 WP_032465607.1 97565..97891(+) (comYC) [Streptococcus pyogenes strain 4958/15]
ATGATTAATCAATGGAACAACTTACGACACAAGAAGCTAAAAGGATTTACTCTTCTAGAAATGTTATTGGTGATTCTTGT
CATCAGTGTTTTGATGCTATTATTTGTGCCTAATTTAAGCAAGCAAAAAGACAGGGTTACAGAAACAGGTAATGCCGCTG
TTGTTAAATTAGTGGAGAATCAAGCAGAACTATATGAATTATCTCAAGGCTCAAAACCAAGTTTGAGCCAGTTAAAGGCA
GATGGTAGTATCACTGAGAAACAAGAAAAAGCTTATCAAGACTATTATAACAAACATAAAAATGAAAAAGCCCGTCTTAG
CAATTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(12-34)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYC Streptococcus gordonii str. Challis substr. CH1

56.19

97.222

0.546
  comGC/cglC Streptococcus mitis SK321

61.957

85.185

0.528
  comGC Lactococcus lactis subsp. cremoris KW2

55.882

94.444

0.528
  comGC/cglC Streptococcus mitis NCTC 12261

60.87

85.185

0.519
  comGC/cglC Streptococcus pneumoniae TIGR4

59.783

85.185

0.509
  comGC/cglC Streptococcus pneumoniae Rx1

59.783

85.185

0.509
  comGC/cglC Streptococcus pneumoniae D39

59.783

85.185

0.509
  comGC/cglC Streptococcus pneumoniae R6

59.783

85.185

0.509
  comYC Streptococcus mutans UA140

55.208

88.889

0.491
  comYC Streptococcus mutans UA159

55.208

88.889

0.491
  comYC Streptococcus suis isolate S10

59.259

75

0.444

Multiple sequence alignment