Detailed information NTG0994357

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: AAYT22_RS02325
• Genome accession: NZ_CP154876
• Coordinates: 449920..450507 (-)
• Length: 195 a.a.
• NCBI ID: WP_374918082.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 20155336
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 444920..455507

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AAYT22_RS02300 (AAYT22_02285)	-	445384..446724 (+)	1341	WP_001017622.1	sensor histidine kinase	-
AAYT22_RS02305 (AAYT22_02290)	blpC	446766..446921 (-)	156	WP_000358817.1	quorum-sensing system pheromone BlpC	-
AAYT22_RS02310 (AAYT22_02295)	-	446978..448339 (-)	1362	WP_001069074.1	bacteriocin secretion accessory protein	-
AAYT22_RS02315 (AAYT22_02300)	comA/nlmT	448350..448997 (-)	648	WP_078064020.1	ATP-binding cassette domain-containing protein	Regulator
AAYT22_RS02320 (AAYT22_02305)	comA/nlmT	449013..450026 (-)	1014	WP_318528993.1	ABC transporter transmembrane domain-containing protein	Regulator
AAYT22_RS02325 (AAYT22_02310)	comA/nlmT	449920..450507 (-)	588	WP_374918082.1	cysteine peptidase family C39 domain-containing protein	Regulator
AAYT22_RS02330 (AAYT22_02315)	blpI	450789..450986 (+)	198	WP_001093259.1	bacteriocin-like peptide BlpI	-
AAYT22_RS02335 (AAYT22_02320)	blpJ	451453..451722 (+)	270	WP_001093248.1	bacteriocin-like peptide BlpJ	-
AAYT22_RS02340 (AAYT22_02325)	blpK	451791..452039 (+)	249	WP_000379965.1	bacteriocin-like peptide BlpK	-
AAYT22_RS02345 (AAYT22_02330)	cipB	452283..452432 (+)	150	WP_001836413.1	bacteriocin-like peptide BlpO	Regulator
AAYT22_RS02350	-	452468..452533 (+)	66	Protein_461	ComC/BlpC family peptide pheromone/bacteriocin	-
AAYT22_RS02355 (AAYT22_02335)	-	452536..452655 (+)	120	WP_000346296.1	PncF family bacteriocin immunity protein	-
AAYT22_RS02360 (AAYT22_02340)	-	453136..453494 (+)	359	Protein_463	immunity protein	-
AAYT22_RS02365 (AAYT22_02345)	-	454123..454506 (+)	384	WP_000877381.1	hypothetical protein	-
AAYT22_RS02370 (AAYT22_02350)	-	454558..455247 (+)	690	WP_000760532.1	CPBP family intramembrane glutamic endopeptidase	-

Sequence

Protein

• Length: 195 a.a.
• Molecular weight: 22314.72 Da
• Isoelectric Point: 9.4885

>NTDB_id=994357 AAYT22_RS02325 WP_374918082.1 449920..450507(-) (comA/nlmT) [Streptococcus pneumoniae strain 20155336]
MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKTNKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDV
PYPFIVHVNKEGKLQHYYVVYQTKKDYLIIGDPDPSVKITKMSKERFFYEWTGVDIFLATKPSYQPHKDKKNGLLSKLPS
SDFQTKISHCLHCSLKLIGHYYQYRWFLLSPRNLG

Nucleotide

• Length: 588 bp

>NTDB_id=994357 AAYT22_RS02325 WP_374918082.1 449920..450507(-) (comA/nlmT) [Streptococcus pneumoniae strain 20155336]
ATGACTTCTTATAAACGTACATTTGTTCCTCAAATAGATGCGAGAGACTGTGGTGTCGCTGCCTTAGCCTCGATTGCTAA
ATTCTATGGTTCAGATTTTTCTCTAGCTCACTTGAGAGAACTTGCAAAGACCAATAAAGAAGGGACGACTGCTCTTGGCA
TTGTAAAAGCCGCTGATGAAATGGGCTTTGAAACAAGACCTGTTCAAGCAGATAAAACGCTCTTTGACATGAGTGATGTC
CCCTATCCATTTATCGTTCACGTTAACAAAGAAGGAAAACTCCAACATTACTATGTTGTCTATCAAACAAAGAAAGACTA
TCTGATTATTGGTGATCCTGACCCTTCTGTAAAAATCACTAAAATGTCAAAAGAACGCTTTTTCTATGAATGGACTGGAG
TAGATATTTTTCTAGCTACCAAACCCAGCTATCAACCCCATAAAGATAAAAAGAATGGTCTACTAAGCAAGCTTCCTTCC
TCTGATTTTCAAACAAAAATCTCTCATTGCTTACATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATAGGTGGTT
CTTACTATCTCCAAGGAATCTTGGATGA

Domains

Predicted by InterproScan.

• Peptidase C39 family (Peptidase_C39) (7-142)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	59.341	93.333	0.554
comA	Streptococcus mitis NCTC 12261	54.891	94.359	0.518
comA	Streptococcus mitis SK321	54.348	94.359	0.513
comA	Streptococcus pneumoniae TIGR4	53.804	94.359	0.508
comA	Streptococcus pneumoniae Rx1	53.804	94.359	0.508
comA	Streptococcus pneumoniae D39	53.804	94.359	0.508
comA	Streptococcus pneumoniae R6	53.804	94.359	0.508
comA	Streptococcus gordonii str. Challis substr. CH1	52.717	94.359	0.497