Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   AAYT22_RS02320 Genome accession   NZ_CP154876
Coordinates   449013..450026 (-) Length   337 a.a.
NCBI ID   WP_318528993.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 20155336     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 444013..455026
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AAYT22_RS02290 (AAYT22_02275) - 444290..444628 (+) 339 WP_000876675.1 LytTR family DNA-binding domain-containing protein -
  AAYT22_RS02295 (AAYT22_02280) comE/blpR 444633..445370 (+) 738 WP_001219122.1 response regulator transcription factor Regulator
  AAYT22_RS02300 (AAYT22_02285) - 445384..446724 (+) 1341 WP_001017622.1 sensor histidine kinase -
  AAYT22_RS02305 (AAYT22_02290) blpC 446766..446921 (-) 156 WP_000358817.1 quorum-sensing system pheromone BlpC -
  AAYT22_RS02310 (AAYT22_02295) - 446978..448339 (-) 1362 WP_001069074.1 bacteriocin secretion accessory protein -
  AAYT22_RS02315 (AAYT22_02300) comA/nlmT 448350..448997 (-) 648 WP_078064020.1 ATP-binding cassette domain-containing protein Regulator
  AAYT22_RS02320 (AAYT22_02305) comA/nlmT 449013..450026 (-) 1014 WP_318528993.1 ABC transporter transmembrane domain-containing protein Regulator
  AAYT22_RS02325 (AAYT22_02310) comA/nlmT 449920..450507 (-) 588 WP_374918082.1 cysteine peptidase family C39 domain-containing protein Regulator
  AAYT22_RS02330 (AAYT22_02315) blpI 450789..450986 (+) 198 WP_001093259.1 bacteriocin-like peptide BlpI -
  AAYT22_RS02335 (AAYT22_02320) blpJ 451453..451722 (+) 270 WP_001093248.1 bacteriocin-like peptide BlpJ -
  AAYT22_RS02340 (AAYT22_02325) blpK 451791..452039 (+) 249 WP_000379965.1 bacteriocin-like peptide BlpK -
  AAYT22_RS02345 (AAYT22_02330) cipB 452283..452432 (+) 150 WP_001836413.1 bacteriocin-like peptide BlpO Regulator
  AAYT22_RS02350 - 452468..452533 (+) 66 Protein_461 ComC/BlpC family peptide pheromone/bacteriocin -
  AAYT22_RS02355 (AAYT22_02335) - 452536..452655 (+) 120 WP_000346296.1 PncF family bacteriocin immunity protein -
  AAYT22_RS02360 (AAYT22_02340) - 453136..453494 (+) 359 Protein_463 immunity protein -
  AAYT22_RS02365 (AAYT22_02345) - 454123..454506 (+) 384 WP_000877381.1 hypothetical protein -

Sequence

Protein


Download         Length: 337 a.a.        Molecular weight: 38270.69 Da        Isoelectric Point: 5.1196

>NTDB_id=994356 AAYT22_RS02320 WP_318528993.1 449013..450026(-) (comA/nlmT) [Streptococcus pneumoniae strain 20155336]
MIFKQKSLIAYIVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYILQQVMSFSRDYLLTVLSQRLSI
DVILSYIRHIFELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLISISIYM
FIIFSFMKPFEKMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQTSLKQGTK
LVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLQSAKVANNRLNEVYLVESEFQVQENPVHSHF
LMGDIEFDDLSYKYGFG

Nucleotide


Download         Length: 1014 bp        

>NTDB_id=994356 AAYT22_RS02320 WP_318528993.1 449013..450026(-) (comA/nlmT) [Streptococcus pneumoniae strain 20155336]
CTGATTTTCAAACAAAAATCTCTCATTGCTTACATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATAGGTGGTTC
TTACTATCTCCAAGGAATCTTGGATGAGTACATTCCAAATCAGATGAAATCAACTTTAGGAATCATCTCAGTTGGTCTGG
TTATCACCTATATCCTCCAACAAGTCATGAGCTTCTCCAGAGATTATCTCCTAACCGTTCTGAGCCAGAGATTAAGCATT
GATGTGATTTTATCCTATATTCGCCATATTTTTGAACTTCCCATGTCTTTCTTTGCGACACGTCGTACAGGAGAAATCAT
TTCACGATTCACAGATGCTAACTCTATTATAGATGCCTTGGCTTCTACCATTCTTTCTCTTTTTCTGGATGTTTCTATTC
TGATTCTTGTAGGAGGCGTCTTACTGGCACAAAACCCTAATCTCTTCCTTCTTTCTCTTATTTCCATTTCTATATACATG
TTCATCATCTTTTCTTTTATGAAACCTTTCGAAAAAATGAACCATGATGTCATGCAAAGTAATTCTATGGTTAGCTCTGC
CATTATCGAAGATATCAACGGGATTGAAACTATAAAGTCGCTCACGAGTGAAGAAAATCGCTATCAAAATATAGACAGCG
AATTTGTAGATTATTTGGAAAAATCCTTTAAGCTCAGTAAATATTCTATTTTACAAACGAGTTTAAAGCAGGGAACAAAA
TTAGTTCTGAATATCCTTATCCTATGGTTTGGCGCTCAATTAGTCATGTCAAGTAAAATTTCTATCGGTCAGCTGATTAC
CTTTAACACACTTTTTTCTTACTTTACAACTCCTATGGAAAATATTATCAACCTCCAAACCAAACTCCAATCTGCGAAGG
TCGCTAATAACCGTTTGAACGAAGTCTATCTAGTCGAATCTGAATTTCAAGTTCAAGAAAACCCTGTTCATTCACATTTT
TTGATGGGCGATATTGAATTTGATGACCTTTCTTATAAGTATGGTTTTGGATGA

Domains

Predicted by InterproScan.

ABC transporter transmembrane region (ABC_membrane)

(10-279)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

72.7

100

0.727
  comA Streptococcus gordonii str. Challis substr. CH1

66.864

100

0.671
  comA Streptococcus mitis NCTC 12261

66.469

100

0.665
  comA Streptococcus pneumoniae Rx1

66.172

100

0.662
  comA Streptococcus pneumoniae D39

66.172

100

0.662
  comA Streptococcus pneumoniae R6

66.172

100

0.662
  comA Streptococcus pneumoniae TIGR4

65.875

100

0.659
  comA Streptococcus mitis SK321

65.875

100

0.659

Multiple sequence alignment