Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   AAYT22_RS02315 Genome accession   NZ_CP154876
Coordinates   448350..448997 (-) Length   215 a.a.
NCBI ID   WP_078064020.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 20155336     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 443350..453997
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AAYT22_RS02285 (AAYT22_02270) - 443685..444014 (-) 330 WP_000132572.1 hypothetical protein -
  AAYT22_RS02290 (AAYT22_02275) - 444290..444628 (+) 339 WP_000876675.1 LytTR family DNA-binding domain-containing protein -
  AAYT22_RS02295 (AAYT22_02280) comE/blpR 444633..445370 (+) 738 WP_001219122.1 response regulator transcription factor Regulator
  AAYT22_RS02300 (AAYT22_02285) - 445384..446724 (+) 1341 WP_001017622.1 sensor histidine kinase -
  AAYT22_RS02305 (AAYT22_02290) blpC 446766..446921 (-) 156 WP_000358817.1 quorum-sensing system pheromone BlpC -
  AAYT22_RS02310 (AAYT22_02295) - 446978..448339 (-) 1362 WP_001069074.1 bacteriocin secretion accessory protein -
  AAYT22_RS02315 (AAYT22_02300) comA/nlmT 448350..448997 (-) 648 WP_078064020.1 ATP-binding cassette domain-containing protein Regulator
  AAYT22_RS02320 (AAYT22_02305) comA/nlmT 449013..450026 (-) 1014 WP_318528993.1 ABC transporter transmembrane domain-containing protein Regulator
  AAYT22_RS02325 (AAYT22_02310) comA/nlmT 449920..450507 (-) 588 WP_374918082.1 cysteine peptidase family C39 domain-containing protein Regulator
  AAYT22_RS02330 (AAYT22_02315) blpI 450789..450986 (+) 198 WP_001093259.1 bacteriocin-like peptide BlpI -
  AAYT22_RS02335 (AAYT22_02320) blpJ 451453..451722 (+) 270 WP_001093248.1 bacteriocin-like peptide BlpJ -
  AAYT22_RS02340 (AAYT22_02325) blpK 451791..452039 (+) 249 WP_000379965.1 bacteriocin-like peptide BlpK -
  AAYT22_RS02345 (AAYT22_02330) cipB 452283..452432 (+) 150 WP_001836413.1 bacteriocin-like peptide BlpO Regulator
  AAYT22_RS02350 - 452468..452533 (+) 66 Protein_461 ComC/BlpC family peptide pheromone/bacteriocin -
  AAYT22_RS02355 (AAYT22_02335) - 452536..452655 (+) 120 WP_000346296.1 PncF family bacteriocin immunity protein -
  AAYT22_RS02360 (AAYT22_02340) - 453136..453494 (+) 359 Protein_463 immunity protein -

Sequence

Protein


Download         Length: 215 a.a.        Molecular weight: 23976.78 Da        Isoelectric Point: 9.2946

>NTDB_id=994355 AAYT22_RS02315 WP_078064020.1 448350..448997(-) (comA/nlmT) [Streptococcus pneumoniae strain 20155336]
MNLTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRHINYLPQQAYIFNGSILENLTLGG
NHMISQEDILKACEVAEIRQDIERMPMGYQTQLSDGAGLSGGQKQRIALARALLTKSPVLILDEATSGLDVLTEKKVIDN
LMSLTDKTILFVAHRLSIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK

Nucleotide


Download         Length: 648 bp        

>NTDB_id=994355 AAYT22_RS02315 WP_078064020.1 448350..448997(-) (comA/nlmT) [Streptococcus pneumoniae strain 20155336]
ATTAATCTCACGATTAAACAAGGAGATAAGGTTAGCCTAGTTGGAGTTAGTGGTTCTGGTAAAACAACTTTAGCCAAAAT
GATTGTCAATTTCTTTGAACCCTACAAAGGGCATATTTCCATCAATCATCAGGATATTAAAAACATTGATAAAAAAGTCT
TGCGCCGTCATATTAATTACCTACCCCAACAAGCCTATATCTTTAATGGCTCTATTTTGGAAAACTTAACCTTGGGCGGT
AATCATATGATTAGTCAAGAAGATATTCTAAAAGCTTGTGAAGTAGCTGAAATCCGTCAAGACATTGAAAGAATGCCTAT
GGGCTATCAAACTCAGCTCTCTGATGGAGCTGGTCTATCAGGAGGACAGAAGCAACGAATCGCTCTCGCTCGTGCTCTTT
TAACTAAATCTCCTGTTTTAATACTAGATGAAGCTACTAGCGGTCTTGATGTCTTGACTGAGAAAAAGGTTATAGATAAT
CTTATGTCTCTAACTGATAAAACCATTCTCTTTGTAGCCCATCGTCTCAGTATAGCCGAACGAACCAACCGTGTCATTGT
TCTTGACCAGGGGAAAATCATTGAAGTTGGTAGTCACCAAGAGTTAATGCAGGCGCAAGGTTTCTACCATCATCTATTCA
ATAAATAA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(1-147)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

71.495

99.535

0.712
  comA Streptococcus mitis NCTC 12261

66.977

100

0.67
  comA Streptococcus pneumoniae Rx1

66.512

100

0.665
  comA Streptococcus pneumoniae D39

66.512

100

0.665
  comA Streptococcus pneumoniae R6

66.512

100

0.665
  comA Streptococcus mitis SK321

66.512

100

0.665
  comA Streptococcus pneumoniae TIGR4

66.047

100

0.66
  comA Streptococcus gordonii str. Challis substr. CH1

66.047

100

0.66
  rcrQ Streptococcus mutans UA159

38.679

98.605

0.381

Multiple sequence alignment