Detailed information NTG0098728

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: R8624_RS02390
• Genome accession: NZ_AP026930
• Coordinates: 463462..463929 (-)
• Length: 155 a.a.
• NCBI ID: WP_317650241.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain PZ900701208
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 458462..468929

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R8624_RS02355 (PC1195_04510)	-	458550..458879 (-)	330	WP_000132575.1	hypothetical protein	-
R8624_RS02360 (PC1195_04520)	-	459155..459493 (+)	339	WP_000682121.1	LytTR family DNA-binding domain-containing protein	-
R8624_RS02365 (PC1195_04530)	comE/blpR	459498..460235 (+)	738	WP_001219126.1	response regulator transcription factor	Regulator
R8624_RS02370 (PC1195_04540)	-	460248..461588 (+)	1341	WP_000275285.1	sensor histidine kinase	-
R8624_RS02375 (PC1195_04550)	blpC	461633..461788 (-)	156	WP_000358814.1	quorum-sensing system pheromone BlpC	-
R8624_RS02380 (PC1195_04560)	-	461845..463206 (-)	1362	WP_050311724.1	bacteriocin secretion accessory protein	-
R8624_RS02385 (PC1195_04570)	comA	463217..463486 (-)	270	WP_317650355.1	hypothetical protein	Regulator
R8624_RS02390 (PC1195_04580)	comA/nlmT	463462..463929 (-)	468	WP_317650241.1	ATP-binding cassette domain-containing protein	Regulator
R8624_RS02395 (PC1195_04590)	comA/nlmT	464134..464841 (-)	708	WP_317650242.1	ABC transporter transmembrane domain-containing protein	Regulator
R8624_RS02400 (PC1195_04600)	comA/nlmT	464786..465373 (-)	588	WP_000205166.1	cysteine peptidase family C39 domain-containing protein	Regulator
R8624_RS02405 (PC1195_04610)	blpI	465655..465852 (+)	198	WP_001093259.1	bacteriocin-like peptide BlpI	-
R8624_RS02410 (PC1195_04630)	blpJ	466319..466588 (+)	270	WP_001093248.1	bacteriocin-like peptide BlpJ	-
R8624_RS02415 (PC1195_04640)	blpU	466657..466887 (+)	231	WP_050243503.1	bacteriocin-like peptide BlpU	-
R8624_RS02420	-	466890..467009 (+)	120	WP_050233614.1	PncF family bacteriocin immunity protein	-
R8624_RS02425 (PC1195_04650)	-	467306..467470 (+)	165	WP_000727118.1	hypothetical protein	-
R8624_RS02430 (PC1195_04660)	-	467467..467871 (+)	405	WP_050311725.1	hypothetical protein	-
R8624_RS02435 (PC1195_04680)	-	468500..468883 (+)	384	WP_000877381.1	hypothetical protein	-

Sequence

Protein

• Length: 155 a.a.
• Molecular weight: 17634.23 Da
• Isoelectric Point: 5.6331

>NTDB_id=98728 R8624_RS02390 WP_317650241.1 463462..463929(-) (comA/nlmT) [Streptococcus pneumoniae strain PZ900701208]
MGDIEFDDLSYKYGFGRDTLTDINLTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRHI
NYLPQQAYIFNGSILENLTLGGNHMISQEDILKACELAEIRQDIERMPMGFKLSSLMELVYQEDRSNESLSLVLF

Nucleotide

• Length: 468 bp

>NTDB_id=98728 R8624_RS02390 WP_317650241.1 463462..463929(-) (comA/nlmT) [Streptococcus pneumoniae strain PZ900701208]
ATGGGCGATATTGAATTTGATGACCTTTCTTATAAGTATGGTTTTGGACGAGATACCTTAACAGATATTAATCTCACGAT
TAAACAAGGAGATAAGGTTAGCCTAGTTGGAGTTAGTGGTTCTGGTAAAACAACTTTAGCCAAAATGATTGTCAATTTCT
TTGAACCCTACAAAGGGCATATTTCCATCAATCATCAGGATATTAAAAACATTGATAAAAAAGTCTTGCGCCGTCATATT
AATTACCTACCACAACAAGCCTATATCTTTAATGGCTCTATTTTGGAAAACTTAACCTTGGGCGGTAATCATATGATTAG
CCAAGAAGATATTCTAAAAGCTTGTGAATTAGCTGAAATCCGTCAAGACATTGAAAGAATGCCTATGGGCTTCAAACTCA
GCTCTCTGATGGAGCTGGTCTATCAGGAGGACAGAAGCAACGAATCGCTCTCGCTCGTGCTCTTTTAA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (20-124)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	70.229	84.516	0.594
comA	Streptococcus mitis NCTC 12261	63.359	84.516	0.535
comA	Streptococcus pneumoniae Rx1	62.595	84.516	0.529
comA	Streptococcus pneumoniae D39	62.595	84.516	0.529
comA	Streptococcus pneumoniae R6	62.595	84.516	0.529
comA	Streptococcus mitis SK321	62.595	84.516	0.529
comA	Streptococcus pneumoniae TIGR4	61.832	84.516	0.523
comA	Streptococcus gordonii str. Challis substr. CH1	57.252	84.516	0.484