Detailed information    

insolico Bioinformatically predicted

Overview


Name   comA   Type   Regulator
Locus tag   R8624_RS02385 Genome accession   NZ_AP026930
Coordinates   463217..463486 (-) Length   89 a.a.
NCBI ID   WP_317650355.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900701208     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context


Location: 458217..468486
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8624_RS02355 (PC1195_04510) - 458550..458879 (-) 330 WP_000132575.1 hypothetical protein -
  R8624_RS02360 (PC1195_04520) - 459155..459493 (+) 339 WP_000682121.1 LytTR family DNA-binding domain-containing protein -
  R8624_RS02365 (PC1195_04530) comE/blpR 459498..460235 (+) 738 WP_001219126.1 response regulator transcription factor Regulator
  R8624_RS02370 (PC1195_04540) - 460248..461588 (+) 1341 WP_000275285.1 sensor histidine kinase -
  R8624_RS02375 (PC1195_04550) blpC 461633..461788 (-) 156 WP_000358814.1 quorum-sensing system pheromone BlpC -
  R8624_RS02380 (PC1195_04560) - 461845..463206 (-) 1362 WP_050311724.1 bacteriocin secretion accessory protein -
  R8624_RS02385 (PC1195_04570) comA 463217..463486 (-) 270 WP_317650355.1 hypothetical protein Regulator
  R8624_RS02390 (PC1195_04580) comA/nlmT 463462..463929 (-) 468 WP_317650241.1 ATP-binding cassette domain-containing protein Regulator
  R8624_RS02395 (PC1195_04590) comA/nlmT 464134..464841 (-) 708 WP_317650242.1 ABC transporter transmembrane domain-containing protein Regulator
  R8624_RS02400 (PC1195_04600) comA/nlmT 464786..465373 (-) 588 WP_000205166.1 cysteine peptidase family C39 domain-containing protein Regulator
  R8624_RS02405 (PC1195_04610) blpI 465655..465852 (+) 198 WP_001093259.1 bacteriocin-like peptide BlpI -
  R8624_RS02410 (PC1195_04630) blpJ 466319..466588 (+) 270 WP_001093248.1 bacteriocin-like peptide BlpJ -
  R8624_RS02415 (PC1195_04640) blpU 466657..466887 (+) 231 WP_050243503.1 bacteriocin-like peptide BlpU -
  R8624_RS02420 - 466890..467009 (+) 120 WP_050233614.1 PncF family bacteriocin immunity protein -
  R8624_RS02425 (PC1195_04650) - 467306..467470 (+) 165 WP_000727118.1 hypothetical protein -
  R8624_RS02430 (PC1195_04660) - 467467..467871 (+) 405 WP_050311725.1 hypothetical protein -

Sequence


Protein


Download         Length: 89 a.a.        Molecular weight: 9968.74 Da        Isoelectric Point: 9.8151

>NTDB_id=98727 R8624_RS02385 WP_317650355.1 463217..463486(-) (comA) [Streptococcus pneumoniae strain PZ900701208]
MALARALLTKSPVLILDKATSGLDVLTEKKVIDNLMSLTDKTILFVAHRLSIAERTNRVIVLDQGKIIEVGSHQELMQAQ
GFYHHLFNK

Nucleotide


Download         Length: 270 bp        

>NTDB_id=98727 R8624_RS02385 WP_317650355.1 463217..463486(-) (comA) [Streptococcus pneumoniae strain PZ900701208]
ATCGCTCTCGCTCGTGCTCTTTTAACTAAATCTCCTGTTTTAATACTAGATAAAGCTACTAGCGGTCTTGATGTCTTGAC
TGAGAAAAAGGTTATAGATAATCTTATGTCCCTAACTGATAAAACCATTCTCTTTGTAGCCCATCGTCTCAGTATAGCCG
AACGAACTAACCGTGTCATTGTTCTTGACCAGGGGAAAATCATTGAAGTTGGTAGTCACCAAGAGTTAATGCAAGCGCAA
GGATTCTACCATCATCTATTCAATAAATAA

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus gordonii str. Challis substr. CH1

70.455

98.876

0.697

  comA/nlmT Streptococcus mutans UA159

69.318

98.876

0.685

  comA Streptococcus mitis NCTC 12261

67.045

98.876

0.663

  comA Streptococcus pneumoniae TIGR4

65.909

98.876

0.652

  comA Streptococcus pneumoniae D39

65.909

98.876

0.652

  comA Streptococcus pneumoniae Rx1

65.909

98.876

0.652

  comA Streptococcus pneumoniae R6

65.909

98.876

0.652

  comA Streptococcus mitis SK321

64.773

98.876

0.64

  rcrQ Streptococcus mutans UA159

43.956

100

0.449


Multiple sequence alignment