Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   R8624_RS02400 Genome accession   NZ_AP026930
Coordinates   464786..465373 (-) Length   195 a.a.
NCBI ID   WP_000205166.1    Uniprot ID   Q9ETN5
Organism   Streptococcus pneumoniae strain PZ900701208     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 459786..470373
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8624_RS02370 (PC1195_04540) - 460248..461588 (+) 1341 WP_000275285.1 sensor histidine kinase -
  R8624_RS02375 (PC1195_04550) blpC 461633..461788 (-) 156 WP_000358814.1 quorum-sensing system pheromone BlpC -
  R8624_RS02380 (PC1195_04560) - 461845..463206 (-) 1362 WP_050311724.1 bacteriocin secretion accessory protein -
  R8624_RS02385 (PC1195_04570) comA 463217..463486 (-) 270 WP_317650355.1 hypothetical protein Regulator
  R8624_RS02390 (PC1195_04580) comA/nlmT 463462..463929 (-) 468 WP_317650241.1 ATP-binding cassette domain-containing protein Regulator
  R8624_RS02395 (PC1195_04590) comA/nlmT 464134..464841 (-) 708 WP_317650242.1 ABC transporter transmembrane domain-containing protein Regulator
  R8624_RS02400 (PC1195_04600) comA/nlmT 464786..465373 (-) 588 WP_000205166.1 cysteine peptidase family C39 domain-containing protein Regulator
  R8624_RS02405 (PC1195_04610) blpI 465655..465852 (+) 198 WP_001093259.1 bacteriocin-like peptide BlpI -
  R8624_RS02410 (PC1195_04630) blpJ 466319..466588 (+) 270 WP_001093248.1 bacteriocin-like peptide BlpJ -
  R8624_RS02415 (PC1195_04640) blpU 466657..466887 (+) 231 WP_050243503.1 bacteriocin-like peptide BlpU -
  R8624_RS02420 - 466890..467009 (+) 120 WP_050233614.1 PncF family bacteriocin immunity protein -
  R8624_RS02425 (PC1195_04650) - 467306..467470 (+) 165 WP_000727118.1 hypothetical protein -
  R8624_RS02430 (PC1195_04660) - 467467..467871 (+) 405 WP_050311725.1 hypothetical protein -
  R8624_RS02435 (PC1195_04680) - 468500..468883 (+) 384 WP_000877381.1 hypothetical protein -
  R8624_RS02440 (PC1195_04690) - 468935..469624 (+) 690 WP_000760515.1 CPBP family intramembrane glutamic endopeptidase -
  R8624_RS02445 (PC1195_04700) blpZ 469666..469914 (+) 249 WP_050311727.1 immunity protein BlpZ -

Sequence

Protein


Download         Length: 195 a.a.        Molecular weight: 22270.71 Da        Isoelectric Point: 9.6188

>NTDB_id=98730 R8624_RS02400 WP_000205166.1 464786..465373(-) (comA/nlmT) [Streptococcus pneumoniae strain PZ900701208]
MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKTNKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDV
PYPFIVHVNKEGKLQHYYVVYQTKKDYLIIGDPDPSVKITKMSKERFFYEWTGVAIFLATKPSYQPHKDKKNGLLSKLPS
SDFQTKISHCLHCSLKLIGHYYQYRWFLLSPRNLG

Nucleotide


Download         Length: 588 bp        

>NTDB_id=98730 R8624_RS02400 WP_000205166.1 464786..465373(-) (comA/nlmT) [Streptococcus pneumoniae strain PZ900701208]
ATGACTTCTTATAAACGTACATTTGTTCCTCAAATAGATGCGAGAGACTGTGGTGTCGCTGCCTTAGCCTCGATTGCTAA
ATTCTATGGTTCAGATTTTTCTCTAGCTCACTTGAGAGAACTTGCAAAGACCAATAAAGAAGGGACGACTGCTCTTGGCA
TTGTAAAAGCCGCTGATGAAATGGGCTTTGAAACAAGACCTGTTCAAGCAGATAAAACGCTCTTTGACATGAGTGATGTC
CCCTATCCATTTATCGTTCACGTTAACAAAGAAGGAAAACTCCAACATTACTATGTTGTCTATCAAACAAAGAAAGACTA
TCTGATTATTGGTGATCCTGACCCTTCTGTAAAAATCACTAAAATGTCAAAAGAACGCTTTTTCTATGAATGGACTGGAG
TAGCTATTTTTCTAGCTACCAAACCCAGCTATCAACCCCATAAAGATAAAAAGAATGGTCTACTAAGCAAGCTTCCTTCC
TCTGATTTTCAAACAAAAATCTCTCATTGCTTACATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATAGGTGGTT
CTTACTATCTCCAAGGAATCTTGGATGA

Domains

Predicted by InterproScan.

Peptidase C39 family (Peptidase_C39)

(7-142)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9ETN5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

59.89

93.333

0.559
  comA Streptococcus mitis NCTC 12261

54.891

94.359

0.518
  comA Streptococcus mitis SK321

54.348

94.359

0.513
  comA Streptococcus pneumoniae TIGR4

53.804

94.359

0.508
  comA Streptococcus pneumoniae Rx1

53.804

94.359

0.508
  comA Streptococcus pneumoniae D39

53.804

94.359

0.508
  comA Streptococcus pneumoniae R6

53.804

94.359

0.508
  comA Streptococcus gordonii str. Challis substr. CH1

52.717

94.359

0.497

Multiple sequence alignment