Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   R8611_RS09020 Genome accession   NZ_AP026927
Coordinates   1768409..1769665 (-) Length   418 a.a.
NCBI ID   WP_000642723.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700178     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1763409..1774665
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8611_RS08995 (PC0174_17660) - 1763467..1763673 (-) 207 WP_000366087.1 hypothetical protein -
  R8611_RS09000 (PC0174_17670) - 1763660..1763821 (-) 162 WP_000289348.1 helix-turn-helix domain-containing protein -
  R8611_RS09005 (PC0174_17680) lytA 1764180..1765136 (-) 957 WP_000405240.1 N-acetylmuramoyl-L-alanine amidase LytA -
  R8611_RS09010 (PC0174_17690) - 1765512..1766882 (-) 1371 WP_050137376.1 MATE family efflux transporter -
  R8611_RS09015 (PC0174_17700) recA 1767188..1768354 (-) 1167 WP_001085463.1 recombinase RecA Machinery gene
  R8611_RS09020 (PC0174_17710) cinA 1768409..1769665 (-) 1257 WP_000642723.1 competence/damage-inducible protein A Machinery gene
  R8611_RS09025 (PC0174_17720) brpA 1769750..1770766 (-) 1017 WP_000239283.1 biofilm formation/cell division transcriptional regulator BrpA -
  R8611_RS09030 (PC0174_17730) - 1770774..1771292 (-) 519 WP_000455538.1 GNAT family N-acetyltransferase -
  R8611_RS09035 (PC0174_17740) tsaE 1771282..1771725 (-) 444 WP_000288232.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  R8611_RS09040 (PC0174_17750) comM 1771811..1772431 (-) 621 WP_000839908.1 hypothetical protein Regulator
  R8611_RS09045 (PC0174_17760) - 1772814..1773677 (-) 864 WP_001093634.1 helix-turn-helix domain-containing protein -
  R8611_RS09050 - 1773871..1774023 (+) 153 WP_152411221.1 PhrA family quorum-sensing system peptide -
  R8611_RS09055 (PC0174_17770) - 1774338..1774634 (+) 297 WP_000911559.1 lactococcin 972 family bacteriocin -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 45060.47 Da        Isoelectric Point: 4.6461

>NTDB_id=98528 R8611_RS09020 WP_000642723.1 1768409..1769665(-) (cinA) [Streptococcus pneumoniae strain PZ900700178]
MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGDNEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQT
LAKFLGKALVFNPQAQEKLDIFFALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLRLSTKASSQEEANQALDILENQI
LDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQGKTIAAAESLTAGLFQATVANFSGVSSIFKGGFVTYSLEEKSRML
DIPAKNLEEHGVVSEFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQDQGTEVIKVNIGGRSRADVR
HIAVMHAFNLVRKALLSD

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=98528 R8611_RS09020 WP_000642723.1 1768409..1769665(-) (cinA) [Streptococcus pneumoniae strain PZ900700178]
ATGAAAGCAGAAATCATTGCTGTTGGAACAGAGATTTTGACAGGGCAGATTGTCAACACCAATGCCCAGTTTTTGTCGGA
AAAACTAGCTGAGATTGGGGTAGATGTATATTTTCAGACGGCTGTAGGAGACAATGAAGTTCGTCTCTTGTCTTTGCTTG
AGATTGCCAGTCAACGTAGTAGTCTGGTGATTTTGACAGGCGGTTTGGGGCCAACTGAGGACGACCTAACCAAACAAACC
CTAGCTAAATTTTTAGGGAAAGCATTAGTCTTTAATCCTCAGGCTCAGGAGAAGTTGGATATCTTTTTTGCCCTGCGACC
AGACTATGCCCGAACACCGAATAACGAAAGACAAGCTCAAATTGTAGAAGGAGCGATTCCACTGCCAAACGAAACAGGAC
TGGCTGTTGGAGGAAAATTAGAAGTAGACGGAGTGACCTATGTCGTCCTTCCAGGTCCGCCAAGTGAATTGAAACCCATG
GTCTTAAACCAACTTCTACCCAAGTTGATGACAGGGAGCAAGCTGTATTCCCGAGTTCTTCGTTTCTTTGGGATTGGCGA
GAGCCAGCTGGTTACGATTTTGGCTGATTTAATTGATAATCAGATCGATCCTACCTTGGCCCCTTATGCCAAGACAGGAG
AAGTCACTCTACGTCTGTCAACAAAGGCTAGCAGTCAAGAAGAGGCGAATCAAGCGCTGGATATCTTGGAAAATCAAATC
TTGGACTGCCAGACTTTCGAAGGAATTTCTTTACGAGACTTTTGCTATGGTTATGGGGAAGAAACTAGTTTAGCCAGCAT
TGTGGTAGAAGAACTGAAAAGGCAAGGGAAAACCATCGCGGCTGCAGAGAGTTTGACGGCAGGTCTTTTCCAAGCTACCG
TGGCGAATTTTTCTGGAGTTTCAAGTATATTTAAGGGTGGTTTTGTGACCTATAGCTTGGAGGAAAAATCAAGGATGTTG
GATATTCCTGCCAAGAATTTGGAAGAACATGGTGTGGTGTCTGAATTTACAGCTCAGAAGATGGCTGAGCAGGCACGAAG
CAAGACCCAGTCTGATTTTGGAATTAGTTTGACTGGAGTGGCAGGACCAGATAGCCTAGAAGGACACCCAGTTGGGACAG
TCTTCATAGGCTTGGCGCAAGATCAAGGAACTGAGGTTATCAAGGTTAATATTGGAGGCAGAAGCCGAGCAGATGTACGT
CACATTGCGGTTATGCATGCCTTTAACCTAGTTCGCAAGGCTTTATTAAGTGACTAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(262-414)

Damage-inducible protein CinA KH domain (CinA_KH)

(177-240)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus pneumoniae TIGR4

99.522

100

0.995
  cinA Streptococcus pneumoniae Rx1

99.282

100

0.993
  cinA Streptococcus pneumoniae R6

99.282

100

0.993
  cinA Streptococcus pneumoniae D39

99.043

100

0.99
  cinA Streptococcus mitis SK321

93.541

100

0.935
  cinA Streptococcus mitis NCTC 12261

93.301

100

0.933
  cinA Streptococcus mutans UA159

70.813

100

0.708
  cinA Streptococcus suis isolate S10

54.808

99.522

0.545
  cinA Bacillus subtilis subsp. subtilis str. 168

45.694

100

0.457

Multiple sequence alignment