Detailed information    

insolico Bioinformatically predicted

Overview

Name   comM   Type   Regulator
Locus tag   R8611_RS09040 Genome accession   NZ_AP026927
Coordinates   1771811..1772431 (-) Length   206 a.a.
NCBI ID   WP_000839908.1    Uniprot ID   A0A0B7M636
Organism   Streptococcus pneumoniae strain PZ900700178     
Function   fratricide immunity (predicted from homology)   
Competence regulation

Genomic Context

Location: 1766811..1777431
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8611_RS09015 (PC0174_17700) recA 1767188..1768354 (-) 1167 WP_001085463.1 recombinase RecA Machinery gene
  R8611_RS09020 (PC0174_17710) cinA 1768409..1769665 (-) 1257 WP_000642723.1 competence/damage-inducible protein A Machinery gene
  R8611_RS09025 (PC0174_17720) brpA 1769750..1770766 (-) 1017 WP_000239283.1 biofilm formation/cell division transcriptional regulator BrpA -
  R8611_RS09030 (PC0174_17730) - 1770774..1771292 (-) 519 WP_000455538.1 GNAT family N-acetyltransferase -
  R8611_RS09035 (PC0174_17740) tsaE 1771282..1771725 (-) 444 WP_000288232.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  R8611_RS09040 (PC0174_17750) comM 1771811..1772431 (-) 621 WP_000839908.1 hypothetical protein Regulator
  R8611_RS09045 (PC0174_17760) - 1772814..1773677 (-) 864 WP_001093634.1 helix-turn-helix domain-containing protein -
  R8611_RS09050 - 1773871..1774023 (+) 153 WP_152411221.1 PhrA family quorum-sensing system peptide -
  R8611_RS09055 (PC0174_17770) - 1774338..1774634 (+) 297 WP_000911559.1 lactococcin 972 family bacteriocin -
  R8611_RS09060 (PC0174_17780) - 1774737..1776752 (+) 2016 WP_000732381.1 bacteriocin-associated integral membrane family protein -
  R8611_RS09065 (PC0174_17790) - 1776754..1777386 (+) 633 WP_000571422.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 206 a.a.        Molecular weight: 23552.72 Da        Isoelectric Point: 10.1254

>NTDB_id=98529 R8611_RS09040 WP_000839908.1 1771811..1772431(-) (comM) [Streptococcus pneumoniae strain PZ900700178]
MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFVSGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLL
INLLGAVLVLSDNLFIKNTLQQELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF

Nucleotide


Download         Length: 621 bp        

>NTDB_id=98529 R8611_RS09040 WP_000839908.1 1771811..1772431(-) (comM) [Streptococcus pneumoniae strain PZ900700178]
ATGAAATCAATGAGAATCTTATTTTTGTTAGCTTTAATTCAAATCAGTTTGAGTAGCTGTTTCCTATGGAAGGAATGCAT
CTTGTCCTTTAAACAAAGTACAGCTTTTTTCATCGGAAGCATGGTTTTCGTTTCAGGAATCTGTGCTGGAGTAAATTATC
TTTATACCCGTAAGCAAGAAGTCCATAGTGTCCTAGCCAGTAAGAAGTCGGTGAAGCTTTTTTACAGTATGTTACTCTTA
ATTAATTTGTTAGGAGCTGTTCTTGTTTTGTCAGATAACTTGTTCATCAAAAATACGCTGCAGCAAGAATTAGTTGACTT
TTTATTGCCATCCTTCTTTTTCCTATTTGGGCTAGATTTGCTGATTTTTTTACCCTTGAAAAAATACGTGCGCGATTTTC
TTGCTATGCTAGACAGAAAAAAGACAGTGTTGGTGACTATTTTAGCAACACTTCTTTTCTTAAGAAATCCAATGACCATT
GTCTCACTTCTGATTTATATTGGACTGGGCTTGTTTTTTGCAGCCTATCTTGTCCCAAATTCGGTTAAGAAGGAAGTTTC
CTTTTATGGTCATATTTTCCGAGATCTTGTATTGGTCATTGTTACGCTCATTTTCTTTTAG

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7M636

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comM Streptococcus pneumoniae D39

100

100

1
  comM Streptococcus pneumoniae R6

100

100

1
  comM Streptococcus pneumoniae TIGR4

100

100

1
  comM Streptococcus mitis NCTC 12261

38.974

94.66

0.369
  comM Streptococcus mitis SK321

38.974

94.66

0.369

Multiple sequence alignment