Detailed information NTG0098531

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: R8611_RS09115
• Genome accession: NZ_AP026927
• Coordinates: 1791104..1792141 (-)
• Length: 345 a.a.
• NCBI ID: WP_000727275.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain PZ900700178
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1786104..1797141

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R8611_RS09090 (PC0174_17840)	-	1786843..1788174 (-)	1332	WP_000390048.1	hemolysin family protein	-
R8611_RS09095 (PC0174_17850)	endA	1788465..1789289 (-)	825	WP_050199562.1	DNA-entry nuclease EndA	Machinery gene
R8611_RS09100 (PC0174_17860)	-	1789328..1789516 (-)	189	WP_001036519.1	DNA-directed RNA polymerase subunit beta	-
R8611_RS09105 (PC0174_17870)	murA	1789509..1790792 (-)	1284	WP_000358028.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
R8611_RS09110 (PC0174_17880)	-	1790816..1791046 (-)	231	WP_000250384.1	DUF1146 family protein	-
R8611_RS09115 (PC0174_17890)	sepM	1791104..1792141 (-)	1038	WP_000727275.1	SepM family pheromone-processing serine protease	Regulator
R8611_RS09120 (PC0174_17900)	coaD	1792125..1792613 (-)	489	WP_050199560.1	pantetheine-phosphate adenylyltransferase	-
R8611_RS09125 (PC0174_17910)	rsmD	1792603..1793142 (-)	540	WP_000706962.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
R8611_RS09130 (PC0174_17920)	asnA	1793207..1794199 (-)	993	WP_000747993.1	aspartate--ammonia ligase	-
R8611_RS09135 (PC0174_17930)	-	1794310..1794993 (-)	684	WP_001016917.1	Bax inhibitor-1/YccA family protein	-
R8611_RS09140 (PC0174_17940)	-	1795049..1795789 (-)	741	WP_000152680.1	RNA methyltransferase	-
R8611_RS09145 (PC0174_17950)	-	1795823..1796101 (+)	279	WP_001174613.1	acylphosphatase	-
R8611_RS09150 (PC0174_17960)	yidC	1796179..1797105 (+)	927	WP_000835941.1	membrane protein insertase YidC	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37609.64 Da
• Isoelectric Point: 4.9590

>NTDB_id=98531 R8611_RS09115 WP_000727275.1 1791104..1792141(-) (sepM) [Streptococcus pneumoniae strain PZ900700178]
MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFT
DIRSAQETTGGSSDVEFMRINQFYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKEILNISDTVTAVNDQTF
DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVISNVPISFSTAGIGGPSAGLMFSL
AIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAK
TIKTDMKIVPVKTLQDAIDYLKNNP

Nucleotide

• Length: 1038 bp

>NTDB_id=98531 R8611_RS09115 WP_000727275.1 1791104..1792141(-) (sepM) [Streptococcus pneumoniae strain PZ900700178]
ATGAAAAAAAAGATTAGATGGCCCTTATACGTCATTGCGGCCTTGATTGTGACTTTCTTGGCATTTGTAGTGCCCTTGCC
TTATTATATAGAGGTTCCAGGTGGTTCGGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATAAGGAAGCTG
GTGCCTATCAATTCGTTACGGTTGGTGTTCAACATGCCACTTTAGCTCATATGATTTATGCTTGGTTGACACCTTTTACA
GATATTCGTAGTGCTCAGGAGACTACAGGTGGTTCTTCCGATGTTGAATTTATGCGAATCAATCAATTCTACATGCAAAC
ATCGCAAAATATGGCCAAGTATCAAGGACTAAAAACAGCTGGTAAGGATATCGAACTCAAGTACTTTGGAGTTTATGTTT
TGAATGTGACGGATAATTCAACCTTTAAAGAGATTCTCAATATCTCTGATACAGTCACAGCAGTCAATGATCAGACCTTT
GATAGTTCCAAAGACTTGATTGATTACGTCAGTTCTCAAAAATTAGGGGATTCCGTCAAGGTCACCTATGAAGAGGATGG
GCAAACCAAGTCTGCAGAAGGAAAAATCATCACCTTGGAAAATGGCAAAAATGGAATTGGAATCGGCTTGATTGACCGTA
CAGAGGTAATCAGCAATGTCCCAATTAGCTTTTCAACAGCTGGTATTGGCGGTCCAAGTGCTGGTCTCATGTTTAGTCTA
GCTATCTATACTCAAATAGCTCACCCAGATCTTCGTAATGGTCGTATTGTTGCCGGTACAGGTACCATTGACCGCGATGG
TAATGTGGGAGACATTGGAGGTATTGATAAGAAGGTTGTAGCTTCGGCTAGGGCAGGTGCTGCTATTTTCTTTGCTCCTG
ATAACCCTGTTAGCGAAGAAGAACAAAAGGCGCATCCGGACGCGAAAAACAACTACCAAACAGCCCTAGAAGCGGCTAAA
ACAATCAAGACGGATATGAAAATCGTGCCCGTTAAAACCCTACAAGATGCGATTGATTACTTGAAAAACAATCCCTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (130-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (230-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	59.357	99.13	0.588