Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   R8611_RS09095 Genome accession   NZ_AP026927
Coordinates   1788465..1789289 (-) Length   274 a.a.
NCBI ID   WP_050199562.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700178     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1783465..1794289
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8611_RS09090 (PC0174_17840) - 1786843..1788174 (-) 1332 WP_000390048.1 hemolysin family protein -
  R8611_RS09095 (PC0174_17850) endA 1788465..1789289 (-) 825 WP_050199562.1 DNA-entry nuclease EndA Machinery gene
  R8611_RS09100 (PC0174_17860) - 1789328..1789516 (-) 189 WP_001036519.1 DNA-directed RNA polymerase subunit beta -
  R8611_RS09105 (PC0174_17870) murA 1789509..1790792 (-) 1284 WP_000358028.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  R8611_RS09110 (PC0174_17880) - 1790816..1791046 (-) 231 WP_000250384.1 DUF1146 family protein -
  R8611_RS09115 (PC0174_17890) sepM 1791104..1792141 (-) 1038 WP_000727275.1 SepM family pheromone-processing serine protease Regulator
  R8611_RS09120 (PC0174_17900) coaD 1792125..1792613 (-) 489 WP_050199560.1 pantetheine-phosphate adenylyltransferase -
  R8611_RS09125 (PC0174_17910) rsmD 1792603..1793142 (-) 540 WP_000706962.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  R8611_RS09130 (PC0174_17920) asnA 1793207..1794199 (-) 993 WP_000747993.1 aspartate--ammonia ligase -

Sequence

Protein


Download         Length: 274 a.a.        Molecular weight: 29951.70 Da        Isoelectric Point: 10.1700

>NTDB_id=98530 R8611_RS09095 WP_050199562.1 1788465..1789289(-) (endA) [Streptococcus pneumoniae strain PZ900700178]
MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSTANSPKIKLSQKKQASEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIV
NGNKTNLDAKVSSKPYADNKTKTVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRVRYRVTLYYASNEDLVPSASQIE
AKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ

Nucleotide


Download         Length: 825 bp        

>NTDB_id=98530 R8611_RS09095 WP_050199562.1 1788465..1789289(-) (endA) [Streptococcus pneumoniae strain PZ900700178]
ATGAACAAAAAAACAAGACAGACACTAATCGGACTGCTAGTGTTATTGCTTTTGTCTACAGGGAGCTATTATATCAAGCA
GATGCAGTCGACAGCTAATAGTCCTAAAATCAAGCTTAGTCAGAAAAAACAAGCGTCTGAAGCTCCTAGTCAAGCATTGG
CAGAGAGTGTCTTAACAGACGCAGTCAAGAGTCAAATAAAGGGGAGTCTGGAGTGGAATGGCTCAGGTGCTTTTATCGTC
AATGGTAATAAAACAAATCTAGATGCCAAGGTTTCAAGTAAGCCCTACGCTGACAATAAAACAAAGACAGTGGGCAAGGA
AACTGTTCCAACCGTAGCTAATGCCCTCTTGTCTAAGGCCACTCGTCAGTACAAGAATCGTAAAGAAACTGGGAATGGTT
CAACTTCTTGGACTCCTCCAGGTTGGCATCAGGTCAAGAATCTAAAGGGCTCTTATACCCATGCAGTCGATAGAGGTCAT
TTGTTAGGCTATGCCTTAATCGGTGGTTTGGATGGTTTTGATGCCTCAACAAGCAATCCTAAAAACATTGCTGTTCAGAC
AGCCTGGGCAAATCAGGCACAAGCCGAGTATTCGACTGGTCAAAACTACTATGAAAGCAAGGTGCGTAAAGCCTTGGACC
AAAACAAGCGTGTCCGTTACCGTGTAACCCTTTACTACGCTTCAAACGAGGATTTAGTTCCCTCAGCTTCACAGATTGAA
GCCAAGTCTTCGGATGGAGAATTGGAATTCAATGTTCTAGTTCCCAATGTTCAAAAGGGACTTCAACTGGATTACCGAAC
TGGAGAAGTAACTGTAACTCAGTAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(75-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

98.175

100

0.982
  endA Streptococcus pneumoniae D39

98.175

100

0.982
  endA Streptococcus pneumoniae R6

98.175

100

0.982
  endA Streptococcus pneumoniae TIGR4

98.175

100

0.982

Multiple sequence alignment