Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   R8566_RS10405 Genome accession   NZ_AP026920
Coordinates   1995621..1996574 (-) Length   317 a.a.
NCBI ID   WP_000345085.1    Uniprot ID   A0A0T9IPY8
Organism   Streptococcus pneumoniae strain PZ900700014     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1990621..2001574
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8566_RS10380 (PC0014_20450) - 1991383..1992006 (-) 624 WP_000932659.1 hypothetical protein -
  R8566_RS10385 (PC0014_20460) jag 1992057..1993043 (-) 987 WP_000260025.1 RNA-binding cell elongation regulator Jag/EloR -
  R8566_RS10390 (PC0014_20470) - 1993062..1993886 (-) 825 WP_000727904.1 membrane protein insertase YidC -
  R8566_RS10395 (PC0014_20480) rnpA 1993861..1994232 (-) 372 WP_000739241.1 ribonuclease P protein component -
  R8566_RS10400 (PC0014_20490) - 1994380..1995570 (-) 1191 WP_000167766.1 acetate kinase -
  R8566_RS10405 (PC0014_20500) comYH 1995621..1996574 (-) 954 WP_000345085.1 class I SAM-dependent methyltransferase Machinery gene
  R8566_RS10410 - 1996635..1997222 (-) 588 Protein_2021 class I SAM-dependent methyltransferase -
  R8566_RS10415 (PC0014_20530) comGG/cglG 1997359..1997772 (-) 414 WP_000265619.1 competence type IV pilus minor pilin ComGG Machinery gene
  R8566_RS10420 (PC0014_20540) comGF/cglF 1997750..1998211 (-) 462 WP_000250523.1 competence type IV pilus minor pilin ComGF Machinery gene
  R8566_RS10425 (PC0014_20550) comGE/cglE 1998174..1998476 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  R8566_RS10430 (PC0014_20560) comGD/cglD 1998439..1998843 (-) 405 WP_000588005.1 competence type IV pilus minor pilin ComGD Machinery gene
  R8566_RS10435 (PC0014_20570) comGC/cglC 1998836..1999162 (-) 327 WP_000738638.1 comG operon protein ComGC Machinery gene
  R8566_RS10440 (PC0014_20580) comGB/cglB 1999164..2000180 (-) 1017 WP_074196785.1 competence type IV pilus assembly protein ComGB Machinery gene
  R8566_RS10445 (PC0014_20590) comGA/cglA/cilD 2000128..2001069 (-) 942 WP_000249564.1 competence type IV pilus ATPase ComGA Machinery gene
  R8566_RS10450 (PC0014_20600) - 2001145..2001510 (-) 366 WP_000286415.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 35703.88 Da        Isoelectric Point: 4.2270

>NTDB_id=97982 R8566_RS10405 WP_000345085.1 1995621..1996574(-) (comYH) [Streptococcus pneumoniae strain PZ900700014]
MDFEKIEQAYIYLLENVQVIQSDLATNFYDALVEQNSIYLDGETELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQT
EPLQANHQFTPDAIALLLVFIVEELFTEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEVDDLLIDLAASMADVIGLQ
AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGFKYLKSDGYAIFLAPSDLLTSPQ
SDLLKVWLKEEASLVAMISLPENLFANAKQSKTIFILQKKNEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI

Nucleotide


Download         Length: 954 bp        

>NTDB_id=97982 R8566_RS10405 WP_000345085.1 1995621..1996574(-) (comYH) [Streptococcus pneumoniae strain PZ900700014]
ATGGATTTTGAAAAAATTGAACAAGCTTATATCTATTTACTAGAGAATGTCCAAGTCATCCAAAGTGATTTGGCGACCAA
CTTTTATGACGCCTTGGTGGAGCAAAATAGCATCTATCTGGATGGTGAAACTGAGCTAAACCAGGTCAAAGACAACAATC
AGGCCCTTAAGCGTTTAGCACTACGCAAAGAAGAATGGCTCAAGACCTACCAGTTTCTCTTGATGAAGGCTGGGCAAACA
GAACCCTTGCAGGCCAATCACCAGTTTACGCCAGATGCTATTGCCTTACTTTTGGTATTTATTGTGGAAGAGTTGTTTAC
AGAGGAGGAAATTACTATCCTCGAAATGGGTTCTGGGATGGGAATTCTAGGCGCTACTTTCTTGACCTCGCTTGATAAAA
AGGTGGATTACTTGGGAATGGAAGTGGATGATTTGCTGATTGATCTGGCAGCTAGCATGGCAGATGTAATTGGTTTGCAG
GCTGGCTTTGTCCAAGGAGATGCCGTTCGCCCACAAATGCTCAAAGAAAGCGATGTGGTCATCAGTGACTTGCCTGTTGG
CTATTATCCTGATGATGCCGTTGCGTCGCGCCATCAAGTTGCTTCTAGCCAAGAACATACTTACGCTCATCACTTGCTCA
TGGAACAAGGGTTTAAGTACCTTAAGTCAGATGGATATGCTATTTTTCTAGCTCCGAGTGATTTGTTGACCAGTCCTCAA
AGTGATTTGTTGAAAGTCTGGTTGAAAGAGGAGGCAAGTCTGGTTGCTATGATTAGTCTGCCTGAAAATCTCTTTGCTAA
TGCCAAACAATCTAAGACTATTTTTATCTTACAGAAGAAAAATGAAATAGCAGTAGAGCCTTTTGTTTATCCACTTGCTA
GCTTGCAAGATGCAAGTGTTTTAATGAAATTTAAAGAAAATTTTCAAAAATGGACTCAAGGTACTGAAATATAA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(69-282)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0T9IPY8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA140

54.313

98.738

0.536
  comYH Streptococcus mutans UA159

53.994

98.738

0.533

Multiple sequence alignment