Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   AAEO81_RS26820 Genome accession   NZ_CP151650
Coordinates   5953034..5954251 (+) Length   405 a.a.
NCBI ID   WP_341960024.1    Uniprot ID   -
Organism   Pseudomonas sp. RC10     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 5953034..5964703 5953034..5954251 within 0


Gene organization within MGE regions


Location: 5953034..5964703
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AAEO81_RS26820 (AAEO81_26820) pilC 5953034..5954251 (+) 1218 WP_341960024.1 type II secretion system F family protein Machinery gene
  AAEO81_RS26825 (AAEO81_26825) pilD 5954254..5955126 (+) 873 WP_341960025.1 A24 family peptidase Machinery gene
  AAEO81_RS26830 (AAEO81_26830) coaE 5955123..5955758 (+) 636 WP_341960027.1 dephospho-CoA kinase -
  AAEO81_RS26835 (AAEO81_26835) yacG 5955755..5955958 (+) 204 WP_166597108.1 DNA gyrase inhibitor YacG -
  AAEO81_RS26840 (AAEO81_26840) - 5956114..5956797 (-) 684 WP_341960031.1 energy-coupling factor ABC transporter permease -
  AAEO81_RS26845 (AAEO81_26845) - 5956909..5957553 (-) 645 WP_341960034.1 hydrolase -
  AAEO81_RS26850 (AAEO81_26850) - 5957709..5958608 (+) 900 WP_166597111.1 LysR family transcriptional regulator -
  AAEO81_RS26855 (AAEO81_26855) - 5958668..5959621 (-) 954 WP_341960035.1 2-hydroxyacid dehydrogenase -
  AAEO81_RS26860 (AAEO81_26860) - 5959654..5960418 (-) 765 WP_166597113.1 SDR family oxidoreductase -
  AAEO81_RS26865 (AAEO81_26865) - 5960460..5961161 (-) 702 WP_341964630.1 fumarylacetoacetate hydrolase family protein -
  AAEO81_RS26870 (AAEO81_26870) - 5961458..5962801 (-) 1344 WP_341960037.1 MFS transporter -
  AAEO81_RS26875 (AAEO81_26875) - 5963124..5964026 (+) 903 WP_341960039.1 AraC family transcriptional regulator -
  AAEO81_RS26880 (AAEO81_26880) - 5964146..5964703 (+) 558 WP_341960041.1 hypothetical protein -

Sequence

Protein


Download         Length: 405 a.a.        Molecular weight: 44222.00 Da        Isoelectric Point: 9.9009

>NTDB_id=979524 AAEO81_RS26820 WP_341960024.1 5953034..5954251(+) (pilC) [Pseudomonas sp. RC10]
MATKAVKVSVYAWEGLDRKGTKVTGELNGHNPALIKAQLRKQGINPTKVRKKSVSIFGGGKKIKPLDIAFFSRQMATMMK
AGVPLLQSFDIISEGTENPKFRKLVDDIKHHVASGHSFATALRQHPQYFDDLFCNLVDAGEQAGALESLLDRVATYKEKT
ESLKAKIKKAMTYPIAVVVVAFVVTGILLVKVVPQFQAIFQGFGADLPAFTLMVISLSEALQSYWYMFLLGLVLAIYIFK
RAYRTSENFRNWLDRLVLKIPIIGPLLYKSAVARFARTLSTTFAAGVPLVDALDSVAGATGNIVFKNAVNTVKQDVSTGM
QLNFSMRSTGVFPTLAVQMTSIGEESGALDAMLDKVATYYEDEVDNMVDGLTALMEPMIMAVLGVIVGGLVVAMYLPIFK
LGSVV

Nucleotide


Download         Length: 1218 bp        

>NTDB_id=979524 AAEO81_RS26820 WP_341960024.1 5953034..5954251(+) (pilC) [Pseudomonas sp. RC10]
ATGGCGACCAAGGCAGTCAAAGTCAGCGTTTACGCTTGGGAGGGCCTGGACAGGAAGGGCACGAAGGTCACCGGCGAGCT
AAACGGACACAATCCAGCCTTGATCAAGGCACAACTACGCAAACAAGGTATCAACCCAACCAAGGTCAGAAAAAAATCCG
TCTCCATTTTTGGGGGAGGAAAAAAAATCAAGCCTTTGGATATTGCTTTTTTTAGCAGACAAATGGCGACTATGATGAAG
GCAGGAGTACCCTTACTTCAATCCTTCGATATCATCAGTGAAGGGACGGAAAATCCAAAATTTCGAAAGCTTGTCGATGA
CATCAAACATCATGTGGCTTCTGGACATAGTTTCGCCACAGCCCTACGCCAGCACCCTCAGTATTTCGATGATTTGTTCT
GCAATCTCGTTGACGCAGGCGAGCAGGCGGGTGCGCTTGAGTCACTTCTTGACCGCGTCGCCACTTACAAAGAAAAAACC
GAATCTCTAAAAGCTAAAATCAAGAAAGCGATGACTTACCCTATTGCAGTTGTAGTCGTAGCATTTGTGGTGACAGGCAT
TTTGTTAGTCAAAGTAGTGCCGCAGTTTCAAGCTATCTTTCAAGGCTTCGGTGCAGACCTGCCAGCGTTTACGCTCATGG
TCATATCTTTGTCCGAGGCGCTTCAAAGTTATTGGTATATGTTTCTCTTAGGACTCGTCCTTGCCATATATATATTTAAG
CGCGCATATAGGACATCTGAAAACTTCCGAAACTGGCTTGATCGGCTGGTATTGAAAATCCCAATTATTGGACCGCTGCT
GTATAAATCGGCAGTGGCTCGGTTCGCCAGGACGCTTTCTACGACTTTCGCCGCGGGCGTTCCGCTCGTCGATGCTTTGG
ACTCAGTCGCAGGCGCGACTGGTAACATTGTTTTTAAAAATGCGGTTAACACAGTCAAGCAAGATGTTTCGACAGGCATG
CAACTGAACTTTTCAATGCGGAGCACTGGTGTCTTCCCAACCCTAGCTGTCCAAATGACATCCATTGGCGAAGAGTCCGG
CGCGCTAGACGCTATGCTCGACAAGGTTGCCACTTACTATGAAGACGAAGTCGATAACATGGTCGACGGACTCACGGCAT
TGATGGAGCCCATGATCATGGCTGTACTGGGCGTAATCGTCGGTGGTCTCGTAGTCGCCATGTATCTCCCCATCTTCAAA
CTCGGCAGCGTCGTCTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(71-194)

Type II secretion system (T2SS), protein F (T2SSF)

(275-397)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

76.296

100

0.763
  pilC Acinetobacter baylyi ADP1

60.784

100

0.612
  pilC Acinetobacter baumannii D1279779

59.406

99.753

0.593
  pilC Legionella pneumophila strain ERS1305867

54.293

97.778

0.531
  pilG Neisseria meningitidis 44/76-A

43.035

99.259

0.427
  pilG Neisseria gonorrhoeae MS11

43.035

99.259

0.427
  pilC Vibrio campbellii strain DS40M4

41.379

100

0.415
  pilC Vibrio cholerae strain A1552

41.481

100

0.415
  pilC Thermus thermophilus HB27

40.15

99.012

0.398

Multiple sequence alignment