Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   AABD46_RS10585 Genome accession   NZ_CP150947
Coordinates   2318660..2318944 (-) Length   94 a.a.
NCBI ID   WP_180793850.1    Uniprot ID   -
Organism   Vibrio parahaemolyticus strain vp-HL-202212     
Function   dsDNA binding (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 2318018..2327988 2318660..2318944 within 0


Gene organization within MGE regions


Location: 2318018..2327988
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AABD46_RS10580 (AABD46_10580) rrtA 2318018..2318569 (+) 552 WP_023624117.1 rhombosortase -
  AABD46_RS10585 (AABD46_10585) comEA 2318660..2318944 (-) 285 WP_180793850.1 ComEA family DNA-binding protein Machinery gene
  AABD46_RS10590 (AABD46_10590) ppiD 2319095..2320954 (-) 1860 WP_042781025.1 peptidylprolyl isomerase -
  AABD46_RS10595 (AABD46_10595) - 2321154..2321426 (-) 273 WP_005382341.1 HU family DNA-binding protein -
  AABD46_RS10600 (AABD46_10600) lon 2321620..2323971 (-) 2352 WP_140103112.1 endopeptidase La -
  AABD46_RS10605 (AABD46_10605) clpX 2324103..2325383 (-) 1281 WP_005460618.1 ATP-dependent protease ATP-binding subunit ClpX -
  AABD46_RS10610 (AABD46_10610) clpP 2325455..2326081 (-) 627 WP_005460620.1 ATP-dependent Clp endopeptidase proteolytic subunit ClpP -
  AABD46_RS10615 (AABD46_10615) tig 2326187..2327491 (-) 1305 WP_005460612.1 trigger factor -
  AABD46_RS10620 (AABD46_10620) - 2327785..2327970 (-) 186 WP_005482581.1 hypothetical protein -

Sequence

Protein


Download         Length: 94 a.a.        Molecular weight: 10248.97 Da        Isoelectric Point: 7.9987

>NTDB_id=974191 AABD46_RS10585 WP_180793850.1 2318660..2318944(-) (comEA) [Vibrio parahaemolyticus strain vp-HL-202212]
MKWILTLCLVVFAPLSLAADTKADKYEGIEITVNINTASAEEIATMLKGIGEKKAQSIVDYRTEHGPFKTAADLTNVKGI
GEATIKKNKDRILL

Nucleotide


Download         Length: 285 bp        

>NTDB_id=974191 AABD46_RS10585 WP_180793850.1 2318660..2318944(-) (comEA) [Vibrio parahaemolyticus strain vp-HL-202212]
ATGAAATGGATTTTAACCTTGTGTTTAGTGGTGTTCGCACCACTCAGTTTGGCCGCTGATACCAAGGCTGATAAATATGA
AGGAATTGAAATTACGGTCAATATCAATACTGCTTCTGCAGAAGAGATAGCAACGATGCTGAAAGGTATTGGCGAAAAGA
AAGCGCAAAGCATAGTTGACTACCGTACTGAGCACGGCCCATTTAAAACAGCAGCTGATTTAACCAATGTAAAAGGAATT
GGTGAAGCAACCATCAAGAAAAACAAAGACCGCATTCTTCTATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(32-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Vibrio parahaemolyticus RIMD 2210633

98.936

100

0.989
  comEA Vibrio campbellii strain DS40M4

76.842

100

0.777
  comEA Vibrio cholerae C6706

62.766

100

0.628
  comEA Vibrio cholerae strain A1552

62.766

100

0.628
  comE Neisseria gonorrhoeae MS11

40

95.745

0.383
  comE Neisseria gonorrhoeae MS11

40

95.745

0.383
  comE Neisseria gonorrhoeae MS11

40

95.745

0.383
  comE Neisseria gonorrhoeae MS11

40

95.745

0.383
  comEA/comE1 Glaesserella parasuis strain SC1401

56.452

65.957

0.372
  comE1/comEA Haemophilus influenzae Rd KW20

56.452

65.957

0.372
  comEA Acinetobacter baylyi ADP1

47.222

76.596

0.362

Multiple sequence alignment