Detailed information NTG0093688

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: LLL8_RS06035
• Genome accession: NZ_AP025700
• Coordinates: 1221435..1222283 (+)
• Length: 282 a.a.
• NCBI ID: WP_251900428.1
• Uniprot ID: -
• Organism: Lactococcus lactis strain L8
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1216435..1227283

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LLL8_RS06010 (LLL8_11710)	ilvN	1217188..1217664 (+)	477	WP_017864493.1	acetolactate synthase small subunit	-
LLL8_RS06015 (LLL8_11720)	ilvC	1217710..1218732 (+)	1023	WP_251900427.1	ketol-acid reductoisomerase	-
LLL8_RS06020 (LLL8_11730)	ilvA	1218789..1220039 (+)	1251	WP_015426407.1	threonine ammonia-lyase IlvA	-
LLL8_RS06025 (LLL8_11740)	budA	1220158..1220868 (+)	711	WP_179107502.1	acetolactate decarboxylase	-
LLL8_RS06030 (LLL8_11750)	-	1220909..1221289 (+)	381	WP_015426409.1	RidA family protein	-
LLL8_RS06035 (LLL8_11760)	dprA	1221435..1222283 (+)	849	WP_251900428.1	DNA-processing protein DprA	Machinery gene
LLL8_RS06040 (LLL8_11770)	topA	1222545..1224677 (+)	2133	WP_003131148.1	type I DNA topoisomerase	-
LLL8_RS06045 (LLL8_11780)	trmFO	1224749..1226092 (+)	1344	WP_003131150.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-
LLL8_RS06050 (LLL8_11790)	xerS	1226137..1227207 (-)	1071	WP_251900429.1	tyrosine recombinase XerS	-

Sequence

Protein

• Length: 282 a.a.
• Molecular weight: 32119.17 Da
• Isoelectric Point: 9.5086

>NTDB_id=93688 LLL8_RS06035 WP_251900428.1 1221435..1222283(+) (dprA) [Lactococcus lactis strain L8]
MITNFDLYRWKKAGMTNLGVNKLLKFFHRYDKKISLRQMGQIAQLKSIPNFIEQYKNQDVSKLREDYKIYPSFSLLDEIY
PERLKEIYNPPVLLFYQGDIRLLKTPKLAFVGSRQASSQGIKAVQKIVTELNQNFTIVSGLAKGIDTASHLSAIKNKIPT
IAVIGTGLDIFYPLENRKIQEYLAKNQLILSEYSVGEKPLRYHFPERNRIIAGLSHGVVVIEAKLRSGSLITCERALEEG
RDIFAVPGNIADGFSDGCNHLIQQGAKLIYQAQDILEEYLYD

Nucleotide

• Length: 849 bp

>NTDB_id=93688 LLL8_RS06035 WP_251900428.1 1221435..1222283(+) (dprA) [Lactococcus lactis strain L8]
ATGATAACAAATTTTGATTTATATCGTTGGAAGAAAGCTGGCATGACCAATTTAGGAGTAAATAAACTTTTAAAATTTTT
TCATAGATATGATAAAAAAATAAGTTTAAGACAAATGGGACAAATAGCACAACTTAAATCAATTCCCAACTTTATTGAAC
AATATAAAAATCAAGACGTAAGTAAACTGAGAGAAGATTATAAAATATACCCATCATTTTCTCTTCTTGATGAAATTTAT
CCCGAAAGGCTCAAGGAAATTTACAATCCACCGGTTCTATTATTTTATCAAGGAGATATAAGACTCTTAAAAACTCCTAA
ATTAGCTTTTGTTGGTAGTCGACAAGCAAGCTCACAAGGAATTAAAGCCGTTCAAAAAATTGTGACAGAGTTGAACCAAA
ATTTTACGATTGTCAGCGGACTCGCTAAAGGAATAGATACAGCAAGTCATCTTTCTGCCATTAAAAATAAAATCCCTACA
ATTGCAGTTATCGGTACAGGCTTAGATATCTTTTATCCTTTAGAAAATCGAAAAATTCAAGAATATCTTGCTAAAAACCA
ACTCATACTATCAGAATATTCAGTCGGAGAAAAACCACTTCGCTATCATTTTCCTGAACGCAATCGTATCATTGCGGGAC
TTTCACATGGTGTAGTAGTGATAGAAGCAAAGTTACGAAGTGGTAGTTTAATTACTTGTGAGCGCGCTCTGGAAGAAGGA
AGAGATATTTTCGCTGTACCAGGAAACATAGCAGATGGATTTTCAGATGGCTGTAATCATCTAATACAACAAGGAGCAAA
ATTAATCTATCAAGCCCAAGATATCTTAGAAGAATATTTGTATGATTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (76-270)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (2-63)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Lactococcus lactis subsp. cremoris KW2	86.879	100	0.869
dprA	Streptococcus mutans UA159	59.353	98.582	0.585
dprA/cilB/dalA	Streptococcus mitis SK321	54.643	99.291	0.543
dprA/cilB/dalA	Streptococcus pneumoniae R6	53.929	99.291	0.535
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	53.929	99.291	0.535
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	53.929	99.291	0.535
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	53.929	99.291	0.535
dprA/cilB/dalA	Streptococcus pneumoniae D39	53.929	99.291	0.535
dprA	Bacillus subtilis subsp. subtilis str. 168	40.364	97.518	0.394
dprA	Legionella pneumophila strain ERS1305867	39.13	97.872	0.383
dprA	Haemophilus influenzae Rd KW20	38.889	95.745	0.372
dprA	Latilactobacillus sakei subsp. sakei 23K	40.784	90.426	0.369