Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   U6115_RS05120 Genome accession   NZ_CP142381
Coordinates   1064448..1065671 (+) Length   407 a.a.
NCBI ID   WP_043578583.1    Uniprot ID   A0A2R2IWA6
Organism   Chromobacterium subtsugae strain ATCC 31532     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1059448..1070671
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U6115_RS05100 (U6115_05100) - 1059710..1060531 (+) 822 WP_043578572.1 inner membrane protein YpjD -
  U6115_RS05105 (U6115_05105) comE 1060592..1060891 (+) 300 WP_043578575.1 ComEA family DNA-binding protein Machinery gene
  U6115_RS05110 (U6115_05110) - 1061308..1062489 (+) 1182 WP_043578577.1 porin -
  U6115_RS05115 (U6115_05115) pilF 1062689..1064395 (+) 1707 WP_043578580.1 type IV-A pilus assembly ATPase PilB Machinery gene
  U6115_RS05120 (U6115_05120) pilC 1064448..1065671 (+) 1224 WP_043578583.1 type II secretion system F family protein Machinery gene
  U6115_RS05125 (U6115_05125) - 1065671..1066591 (+) 921 WP_043578586.1 prepilin peptidase -
  U6115_RS05130 (U6115_05130) coaE 1066576..1067190 (+) 615 WP_043578588.1 dephospho-CoA kinase -
  U6115_RS05135 (U6115_05135) zapD 1067226..1067984 (+) 759 WP_043578820.1 cell division protein ZapD -
  U6115_RS05140 (U6115_05140) yacG 1067990..1068184 (+) 195 WP_043578592.1 DNA gyrase inhibitor YacG -
  U6115_RS05145 (U6115_05145) - 1068252..1069493 (-) 1242 WP_043578595.1 N-acetylmuramoyl-L-alanine amidase -
  U6115_RS05150 (U6115_05150) tsaE 1069451..1069939 (-) 489 WP_369816073.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -

Sequence

Protein


Download         Length: 407 a.a.        Molecular weight: 44909.70 Da        Isoelectric Point: 10.0197

>NTDB_id=925617 U6115_RS05120 WP_043578583.1 1064448..1065671(+) (pilC) [Chromobacterium subtsugae strain ATCC 31532]
MATTAAKKTNPGYIWEWEGKDRAGKAIRGELRAESETVAKTQLRRQGINVSKIRKRRTGFGKRITEKDIALFTRQLSTMM
RAGVPLLQAFDIAAKGHSNPAVTRMLLEVRADVETGLSLAEAFRKRPLYFDKLFCNIIAAGETGGVLDTLLDKLATYKEK
VMAIKAKIKSAMIYPSAIVGTAFIITAVIMIYVIPAFKDLFSSFGANLPAPTLFVIWLSDQFVHFWWLIFGTIFGGLFAF
FYAFKRTPKMQEQMDRILLRLPVIGDIIRKATIARWARTLSTLFSAGVPLVEALDSVGGAAGNQVYAEATRRIQADVSTG
SSLNYSMQRTDLFPNMVLQMTSIGEESGSLDQMLDKVADFYEEEVDNAVAALSSLLEPAIMVILGVLIGGLVIAMYMPIF
KMGQVVG

Nucleotide


Download         Length: 1224 bp        

>NTDB_id=925617 U6115_RS05120 WP_043578583.1 1064448..1065671(+) (pilC) [Chromobacterium subtsugae strain ATCC 31532]
ATGGCGACGACAGCTGCGAAAAAGACGAATCCCGGCTACATCTGGGAATGGGAAGGGAAAGACCGGGCCGGCAAGGCGAT
ACGCGGAGAATTGCGCGCCGAGTCGGAAACCGTGGCCAAGACTCAATTGCGGCGCCAAGGCATCAACGTATCCAAAATCC
GCAAGCGCCGCACCGGCTTCGGCAAGCGGATCACCGAAAAGGACATTGCGTTGTTCACGCGCCAACTGTCGACGATGATG
CGGGCGGGGGTGCCGCTGCTGCAGGCTTTCGACATCGCGGCGAAAGGCCACAGCAATCCGGCGGTGACGCGGATGCTGCT
GGAGGTGCGCGCCGACGTGGAAACCGGGCTGTCGCTGGCCGAGGCCTTCCGCAAGCGCCCGCTGTATTTCGACAAGCTGT
TCTGCAACATCATCGCCGCCGGCGAAACCGGCGGCGTGCTGGACACGCTGCTGGACAAGCTCGCCACCTACAAGGAAAAG
GTGATGGCGATCAAGGCCAAGATCAAGTCGGCGATGATCTACCCGTCGGCCATCGTCGGCACCGCTTTCATCATCACCGC
GGTGATCATGATCTACGTGATCCCGGCCTTCAAGGACCTGTTCTCCAGCTTCGGCGCCAATCTGCCGGCGCCGACGCTGT
TCGTGATCTGGCTGTCCGATCAGTTCGTCCATTTCTGGTGGCTGATCTTCGGCACGATTTTCGGCGGCCTGTTCGCCTTC
TTTTACGCGTTCAAACGCACCCCCAAGATGCAGGAGCAGATGGACCGCATCCTGCTGCGGCTGCCGGTGATAGGCGACAT
CATCCGCAAGGCCACCATCGCGCGCTGGGCGCGCACGCTGTCCACGCTGTTTTCCGCCGGCGTGCCGCTGGTGGAGGCGC
TGGATTCGGTGGGCGGCGCCGCCGGCAACCAGGTGTACGCCGAGGCCACGCGCCGGATCCAGGCTGATGTCAGCACCGGC
TCCAGTCTCAACTATTCGATGCAGCGCACCGATCTGTTCCCCAATATGGTGCTACAGATGACCTCGATAGGCGAGGAGTC
CGGCTCGCTGGACCAGATGCTGGACAAGGTGGCCGACTTTTACGAAGAAGAAGTGGATAATGCGGTGGCCGCGCTGTCCA
GCCTGCTGGAGCCGGCCATCATGGTGATACTGGGGGTATTGATCGGCGGTCTGGTGATCGCGATGTACATGCCTATTTTC
AAAATGGGTCAGGTGGTGGGTTGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(276-398)

Type II secretion system (T2SS), protein F (T2SSF)

(72-195)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2R2IWA6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

53.465

99.263

0.531
  pilC Legionella pneumophila strain ERS1305867

52.723

99.263

0.523
  pilG Neisseria meningitidis 44/76-A

52.43

96.069

0.504
  pilG Neisseria gonorrhoeae MS11

52.43

96.069

0.504
  pilC Acinetobacter baylyi ADP1

50.123

100

0.501
  pilC Acinetobacter baumannii D1279779

48.894

100

0.489
  pilC Vibrio campbellii strain DS40M4

38.107

100

0.386
  pilC Vibrio cholerae strain A1552

37.897

100

0.381
  pilC Thermus thermophilus HB27

37.594

98.034

0.369