Detailed information NTG0092531

Bioinformatically predicted

Overview

• Name: comGA
• Type: Machinery gene
• Locus tag: Llc71_RS12250
• Genome accession: NZ_AP025520
• Coordinates: 2372245..2373225 (-)
• Length: 326 a.a.
• NCBI ID: WP_248536775.1
• Uniprot ID: -
• Organism: Lactococcus cremoris strain 7-1
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2367245..2378225

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Llc71_RS12230 (Llc71_24440)	-	2368324..2369211 (+)	888	WP_248536772.1	S24 family peptidase	-
Llc71_RS12235 (Llc71_24450)	-	2369269..2369592 (+)	324	WP_248536773.1	hypothetical protein	-
Llc71_RS12240 (Llc71_24460)	-	2369714..2371171 (+)	1458	WP_248536774.1	recombinase family protein	-
Llc71_RS13825 (Llc71_24470)	comGC	2371168..2371302 (-)	135	WP_259683622.1	hypothetical protein	Machinery gene
Llc71_RS12245 (Llc71_24480)	comGB	2371320..2372345 (-)	1026	WP_042211510.1	competence type IV pilus assembly protein ComGB	Machinery gene
Llc71_RS12250 (Llc71_24490)	comGA	2372245..2373225 (-)	981	WP_248536775.1	competence type IV pilus ATPase ComGA	Machinery gene

Sequence

Protein

• Length: 326 a.a.
• Molecular weight: 37009.33 Da
• Isoelectric Point: 6.1792

>NTDB_id=92531 Llc71_RS12250 WP_248536775.1 2372245..2373225(-) (comGA) [Lactococcus cremoris strain 7-1]
MVQKKAQELIQKAIEMVASDIYLIASGNLYKIYIRQQLGRTLIEEVNQEIGLALFTHFKFLAGMNTGERRRVQLGACWYE
LEGSSTKRLRLSTVGDFEGNESLVIRLLHDQKQELEFWFDDKLQDFRCKRGLYLFAGPVGSGKTSLMFDLAHRHFSNAQV
ITIEEPVELIDSDFIQLQVNDVIGNSYDELIKLSLRHRPDLLIVGEIRDQQTARAVLRASLTGYTVFSTIHAASVKGVVQ
RLLELGLSDWELKNGLEAVVYQRLIAGKGVLDIAKSKFDTWSPKKWNEKIENLYANGHLTAIEAEREKISINQASKIDTT
DGESFE

Nucleotide

• Length: 981 bp

>NTDB_id=92531 Llc71_RS12250 WP_248536775.1 2372245..2373225(-) (comGA) [Lactococcus cremoris strain 7-1]
ATGGTACAGAAAAAAGCACAAGAACTCATTCAAAAGGCAATTGAGATGGTGGCTTCTGATATTTATTTAATTGCTTCAGG
AAATCTTTATAAGATATATATTCGTCAACAATTAGGGCGAACTTTAATAGAGGAAGTTAACCAAGAGATTGGTTTAGCAT
TATTTACTCATTTTAAATTTCTTGCTGGCATGAATACTGGTGAACGCCGGCGTGTTCAGCTGGGTGCTTGTTGGTATGAA
CTAGAGGGAAGTTCGACAAAACGTTTGCGCCTTTCAACAGTGGGAGATTTTGAAGGAAACGAATCATTGGTTATCCGTCT
TCTGCATGACCAAAAACAAGAACTTGAGTTTTGGTTTGATGATAAACTTCAGGATTTTCGATGTAAACGAGGACTTTATT
TATTTGCTGGGCCAGTAGGGTCTGGGAAAACTTCACTAATGTTTGACTTAGCCCACCGTCATTTTTCAAATGCACAGGTT
ATCACTATTGAGGAGCCTGTAGAATTAATTGATTCTGATTTTATTCAGTTACAAGTTAATGATGTAATTGGGAATAGTTA
TGATGAATTAATTAAACTTTCTTTAAGACACCGACCAGATTTACTAATTGTTGGAGAAATTCGAGATCAGCAGACAGCTC
GTGCTGTATTGCGTGCAAGTTTAACAGGCTATACAGTTTTTTCTACTATTCATGCGGCTTCCGTGAAGGGAGTGGTTCAA
CGTTTGTTGGAATTGGGTTTGAGTGATTGGGAATTAAAAAATGGATTAGAGGCAGTTGTTTATCAACGGTTAATAGCGGG
AAAAGGAGTATTAGATATTGCGAAAAGTAAATTTGACACTTGGTCGCCGAAAAAATGGAATGAAAAGATTGAGAACTTAT
ATGCAAACGGACATCTTACGGCTATTGAGGCCGAAAGGGAAAAAATTAGCATTAATCAAGCAAGCAAAATTGATACAACT
GATGGGGAATCTTTTGAATAA

Domains

Predicted by InterproScan.

• Type II/IV secretion system protein (T2SSE) (9-265)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGA	Lactococcus lactis subsp. cremoris KW2	99.08	100	0.991
comGA/cglA	Streptococcus sobrinus strain NIDR 6715-7	56.452	95.092	0.537
comYA	Streptococcus gordonii str. Challis substr. CH1	54.43	96.933	0.528
comGA/cglA/cilD	Streptococcus pneumoniae Rx1	54.487	95.706	0.521
comGA/cglA/cilD	Streptococcus pneumoniae D39	54.487	95.706	0.521
comGA/cglA/cilD	Streptococcus pneumoniae R6	54.487	95.706	0.521
comGA/cglA/cilD	Streptococcus pneumoniae TIGR4	54.487	95.706	0.521
comGA/cglA/cilD	Streptococcus mitis NCTC 12261	54.487	95.706	0.521
comYA	Streptococcus mutans UA159	52.412	95.399	0.5
comYA	Streptococcus mutans UA140	52.412	95.399	0.5