Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   VOI49_RS10155 Genome accession   NZ_CP142018
Coordinates   2022393..2023664 (-) Length   423 a.a.
NCBI ID   WP_226313886.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae strain lu24     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 2017393..2028664
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VOI49_RS10125 - 2017482..2019044 (-) 1563 WP_324739004.1 DUF2079 domain-containing protein -
  VOI49_RS10130 - 2019389..2019694 (-) 306 WP_003053101.1 DUF1292 domain-containing protein -
  VOI49_RS10135 ruvX 2019705..2020124 (-) 420 WP_003053103.1 Holliday junction resolvase RuvX -
  VOI49_RS10140 - 2020121..2020390 (-) 270 WP_003045720.1 IreB family regulatory phosphoprotein -
  VOI49_RS10145 spx 2020502..2020900 (-) 399 WP_003053105.1 transcriptional regulator Spx -
  VOI49_RS10150 recA 2021199..2022335 (-) 1137 WP_226313885.1 recombinase RecA Machinery gene
  VOI49_RS10155 cinA 2022393..2023664 (-) 1272 WP_226313886.1 competence/damage-inducible protein A Machinery gene
  VOI49_RS10160 - 2023860..2024144 (-) 285 WP_226313887.1 VOC family protein -
  VOI49_RS10165 - 2024144..2024716 (-) 573 WP_115253192.1 DNA-3-methyladenine glycosylase I -
  VOI49_RS10170 ruvA 2024726..2025319 (-) 594 WP_226313888.1 Holliday junction branch migration protein RuvA -
  VOI49_RS10175 - 2025321..2026541 (-) 1221 WP_226313889.1 MDR family MFS transporter -
  VOI49_RS10180 mutL 2026552..2028534 (-) 1983 WP_226313900.1 DNA mismatch repair endonuclease MutL -

Sequence

Protein


Download         Length: 423 a.a.        Molecular weight: 46000.52 Da        Isoelectric Point: 4.7611

>NTDB_id=921043 VOI49_RS10155 WP_226313886.1 2022393..2023664(-) (cinA) [Streptococcus dysgalactiae strain lu24]
MKAELIAVGTEILTGQIVNTNAQFLSEKMAELGIDVYFQTAVGDNEERLLSVIATASQRSDLVILCGGLGPTEDDLTKQT
LAKYLNRDLVFEEEASQKLDDFYASRKESSRTANNAKQAQIIAGSSPLQNRTGLAVGGLITVNKVTYVILPGPPSELKPM
VNEELLPLLSTQSRKLYSRVLRFFGIGESQLVTVLSDLIENQTDPTIAPYAKTGEVTLRLSTKAESQTLADTKLDQLEAQ
LLSRKTPDNQSLSDFLYGYREDNSLAREVFELLVKYDKTITAAESLTAGLFQSTLASFPGASQVFNGGFVTYSMEEKAKM
LGIPLEDLTSYGVVSAYTAEKMAEQARLLTGADIGISLTGVAGPDMLENQPAGTVFIGLAIQNKVESMKVLIGGRSRSDV
RHIATLHAFNMVRKTLLKPENLL

Nucleotide


Download         Length: 1272 bp        

>NTDB_id=921043 VOI49_RS10155 WP_226313886.1 2022393..2023664(-) (cinA) [Streptococcus dysgalactiae strain lu24]
ATGAAAGCTGAACTGATTGCAGTAGGTACCGAAATTTTGACTGGTCAAATTGTGAATACTAATGCTCAATTTCTGTCGGA
AAAAATGGCAGAGCTAGGTATTGATGTCTATTTTCAAACGGCTGTTGGGGACAACGAGGAGCGTTTACTTTCAGTGATTG
CAACTGCTAGTCAGCGGAGTGATTTGGTCATTTTATGTGGTGGTCTTGGCCCCACAGAAGATGATTTAACCAAGCAGACT
TTAGCAAAATACCTTAATAGAGATTTGGTCTTTGAAGAAGAAGCTAGTCAAAAATTAGACGATTTTTATGCCAGTCGTAA
AGAGTCGTCTCGAACGGCAAATAATGCTAAGCAGGCTCAGATCATTGCTGGTTCAAGCCCTCTGCAAAATAGAACAGGAC
TCGCAGTGGGGGGCTTAATCACTGTTAATAAGGTGACTTATGTTATTTTACCAGGGCCGCCAAGTGAATTAAAACCTATG
GTTAATGAGGAACTGCTTCCTCTTTTGTCCACACAATCTCGCAAACTTTACTCGAGAGTCTTACGATTTTTTGGGATTGG
TGAGAGTCAGCTGGTGACGGTCTTATCAGACCTTATTGAGAATCAAACTGACCCTACCATTGCACCTTATGCCAAAACTG
GTGAAGTGACCCTTCGTTTATCAACGAAAGCTGAAAGTCAAACATTAGCAGATACGAAATTAGATCAACTAGAAGCGCAG
CTATTGTCGCGAAAAACTCCTGACAACCAGTCGTTATCAGATTTTCTTTATGGCTATAGAGAGGATAATTCCTTAGCGCG
TGAGGTATTTGAGCTCTTAGTAAAATATGATAAGACAATTACAGCAGCAGAAAGTCTAACCGCGGGATTATTTCAGTCAA
CTTTGGCGAGTTTTCCAGGAGCTTCTCAAGTATTCAATGGAGGCTTTGTGACTTATAGCATGGAAGAAAAAGCGAAAATG
CTAGGCATTCCTCTAGAGGATTTGACATCGTATGGAGTTGTTAGTGCTTATACGGCTGAGAAGATGGCGGAGCAAGCAAG
ATTATTGACTGGTGCTGATATTGGGATAAGTTTAACAGGTGTTGCCGGACCAGATATGTTGGAGAACCAGCCTGCAGGTA
CAGTTTTCATTGGTCTTGCCATTCAAAATAAGGTAGAATCCATGAAGGTTTTAATCGGGGGACGGAGCCGTTCAGATGTG
CGTCATATTGCGACTTTACATGCTTTTAATATGGTCCGTAAAACTTTATTAAAACCTGAAAATTTGCTATAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(263-416)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-243)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

72.34

100

0.723
  cinA Streptococcus mitis SK321

71.223

98.582

0.702
  cinA Streptococcus mitis NCTC 12261

70.024

98.582

0.69
  cinA Streptococcus pneumoniae TIGR4

69.305

98.582

0.683
  cinA Streptococcus pneumoniae Rx1

69.305

98.582

0.683
  cinA Streptococcus pneumoniae R6

69.305

98.582

0.683
  cinA Streptococcus pneumoniae D39

69.065

98.582

0.681
  cinA Streptococcus suis isolate S10

53.606

98.345

0.527
  cinA Bacillus subtilis subsp. subtilis str. 168

46.411

98.818

0.459