Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   VF946_RS05675 Genome accession   NZ_CP141824
Coordinates   1077676..1078338 (-) Length   220 a.a.
NCBI ID   WP_024405509.1    Uniprot ID   -
Organism   Streptococcus suis strain HB18     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 1063106..1078338 1077676..1078338 within 0


Gene organization within MGE regions


Location: 1063106..1078338
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VF946_RS05600 - 1063106..1063471 (-) 366 WP_002303448.1 GNAT family N-acetyltransferase -
  VF946_RS05605 - 1063497..1064762 (-) 1266 Protein_1072 DNA topoisomerase -
  VF946_RS05610 - 1064968..1066287 (-) 1320 WP_002338419.1 IS1380-like element ISSsu5 family transposase -
  VF946_RS05615 - 1066515..1067042 (-) 528 WP_002294507.1 phosphoribosyltransferase family protein -
  VF946_RS05620 - 1067086..1067949 (-) 864 WP_002294505.1 aminoglycoside nucleotidyltransferase ANT(6)-Ia -
  VF946_RS05625 - 1067982..1068716 (-) 735 WP_024411460.1 class I SAM-dependent methyltransferase -
  VF946_RS05630 - 1068697..1069471 (-) 775 Protein_1077 nucleotidyltransferase domain-containing protein -
  VF946_RS05635 lnu(B) 1069703..1070506 (-) 804 WP_002294514.1 lincosamide nucleotidyltransferase Lnu(B) -
  VF946_RS05640 lsa(E) 1070560..1072044 (-) 1485 WP_002294513.1 ABC-F type ribosomal protection protein Lsa(E) -
  VF946_RS05645 - 1072487..1073071 (-) 585 WP_002294511.1 recombinase zinc beta ribbon domain-containing protein -
  VF946_RS05650 - 1073142..1073591 (+) 450 WP_242952495.1 hypothetical protein -
  VF946_RS05655 - 1073642..1073893 (-) 252 WP_002294510.1 hypothetical protein -
  VF946_RS05660 - 1074017..1075171 (-) 1155 WP_105140797.1 helix-turn-helix domain-containing protein -
  VF946_RS05665 - 1075253..1075888 (-) 636 WP_105140796.1 CpXC domain-containing protein -
  VF946_RS05670 comEC/celB 1076013..1077692 (-) 1680 WP_395424540.1 ComEC/Rec2 family competence protein Machinery gene
  VF946_RS05675 comEA/celA/cilE 1077676..1078338 (-) 663 WP_024405509.1 helix-hairpin-helix domain-containing protein Machinery gene

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 23233.97 Da        Isoelectric Point: 4.1447

>NTDB_id=919754 VF946_RS05675 WP_024405509.1 1077676..1078338(-) (comEA/celA/cilE) [Streptococcus suis strain HB18]
MDTIKTYIEMLKEYKWQIALPTVAGLLMATFLIFSQPAKSDQTGLTDFPQTAQTSSSSDLVEETSTEASEEPSQLVVDVK
GAVVKPGLYTLEAGARVNDAVEAAGGLTSQADPKSINLAQKLSDEAVVYVASKDENISVVASTTASSAMSPEEKSTSLVN
LNTATEADLQTISGIGAKRAADIIAYREANGGFKSVNDLNNVSGIGDKTMESIRPYVTVE

Nucleotide


Download         Length: 663 bp        

>NTDB_id=919754 VF946_RS05675 WP_024405509.1 1077676..1078338(-) (comEA/celA/cilE) [Streptococcus suis strain HB18]
ATGGATACGATTAAAACTTATATAGAAATGCTTAAAGAATACAAGTGGCAAATTGCTCTGCCCACAGTGGCTGGCTTGCT
AATGGCGACGTTCTTAATATTCAGTCAACCAGCCAAGTCTGACCAGACAGGACTGACAGATTTTCCGCAGACCGCACAAA
CTTCTAGCAGCTCTGACTTGGTCGAGGAAACCAGTACAGAAGCAAGTGAGGAACCCAGCCAGCTGGTCGTTGATGTCAAA
GGAGCGGTAGTAAAACCAGGGCTCTACACTTTAGAAGCTGGTGCGCGTGTCAATGACGCAGTTGAAGCAGCTGGCGGCTT
GACCAGTCAGGCAGACCCCAAGTCTATCAATCTGGCTCAGAAGCTCAGCGATGAGGCGGTGGTCTATGTAGCCAGCAAGG
ACGAAAACATCTCGGTGGTGGCCAGCACGACTGCCAGCTCTGCTATGTCTCCAGAAGAAAAAAGCACCAGTCTGGTCAAT
CTGAATACGGCGACTGAGGCGGACTTGCAGACCATTTCGGGTATCGGTGCCAAGCGGGCGGCGGACATTATCGCCTATCG
TGAGGCAAACGGTGGCTTCAAGTCGGTGAACGACCTCAACAATGTTTCGGGCATTGGCGACAAGACCATGGAAAGCATTC
GGCCTTATGTCACGGTTGAGTAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(157-218)

SLBB domain (SLBB)

(76-130)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus mitis NCTC 12261

48.402

99.545

0.482
  comEA/celA/cilE Streptococcus pneumoniae Rx1

48.402

99.545

0.482
  comEA/celA/cilE Streptococcus pneumoniae D39

48.402

99.545

0.482
  comEA/celA/cilE Streptococcus pneumoniae R6

48.402

99.545

0.482
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

48.624

99.091

0.482
  comEA/celA/cilE Streptococcus mitis SK321

45.946

100

0.464
  comEA Streptococcus thermophilus LMD-9

59.259

73.636

0.436
  comEA Lactococcus lactis subsp. cremoris KW2

36.283

100

0.373
  comEA Bacillus subtilis subsp. subtilis str. 168

37.915

95.909

0.364