Detailed information NTG0919753

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: VF946_RS05670
• Genome accession: NZ_CP141824
• Coordinates: 1076013..1077692 (-)
• Length: 559 a.a.
• NCBI ID: WP_395424540.1
• Uniprot ID: -
• Organism: Streptococcus suis strain HB18
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
Genomic island	1063106..1078338	1076013..1077692	within	0

Gene organization within MGE regions

Location: 1063106..1078338

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
VF946_RS05600	-	1063106..1063471 (-)	366	WP_002303448.1	GNAT family N-acetyltransferase	-
VF946_RS05605	-	1063497..1064762 (-)	1266	Protein_1072	DNA topoisomerase	-
VF946_RS05610	-	1064968..1066287 (-)	1320	WP_002338419.1	IS1380-like element ISSsu5 family transposase	-
VF946_RS05615	-	1066515..1067042 (-)	528	WP_002294507.1	phosphoribosyltransferase family protein	-
VF946_RS05620	-	1067086..1067949 (-)	864	WP_002294505.1	aminoglycoside nucleotidyltransferase ANT(6)-Ia	-
VF946_RS05625	-	1067982..1068716 (-)	735	WP_024411460.1	class I SAM-dependent methyltransferase	-
VF946_RS05630	-	1068697..1069471 (-)	775	Protein_1077	nucleotidyltransferase domain-containing protein	-
VF946_RS05635	lnu(B)	1069703..1070506 (-)	804	WP_002294514.1	lincosamide nucleotidyltransferase Lnu(B)	-
VF946_RS05640	lsa(E)	1070560..1072044 (-)	1485	WP_002294513.1	ABC-F type ribosomal protection protein Lsa(E)	-
VF946_RS05645	-	1072487..1073071 (-)	585	WP_002294511.1	recombinase zinc beta ribbon domain-containing protein	-
VF946_RS05650	-	1073142..1073591 (+)	450	WP_242952495.1	hypothetical protein	-
VF946_RS05655	-	1073642..1073893 (-)	252	WP_002294510.1	hypothetical protein	-
VF946_RS05660	-	1074017..1075171 (-)	1155	WP_105140797.1	helix-turn-helix domain-containing protein	-
VF946_RS05665	-	1075253..1075888 (-)	636	WP_105140796.1	CpXC domain-containing protein	-
VF946_RS05670	comEC/celB	1076013..1077692 (-)	1680	WP_395424540.1	ComEC/Rec2 family competence protein	Machinery gene
VF946_RS05675	comEA/celA/cilE	1077676..1078338 (-)	663	WP_024405509.1	helix-hairpin-helix domain-containing protein	Machinery gene

Sequence

Protein

• Length: 559 a.a.
• Molecular weight: 63172.54 Da
• Isoelectric Point: 8.9424

>NTDB_id=919753 VF946_RS05670 WP_395424540.1 1076013..1077692(-) (comEC/celB) [Streptococcus suis strain HB18]
MSRLSKLPCQPVHLAVLAVAAYFAVHSFSLLTMCLLSLVLAVFGVRQGKTVFLKTLPLLTLCGLFFGCQKVQWERAAQSA
PEQVTTVQVIPDTIDINGDSLSFRGRADGQNYQVFYKLTSQEEQTYFQNLADLVQLEVEAEVSLPAGQRNFKGFDYQAYL
KTQGIYRTVKLTAIKKIVPVQSWNVFDWLSTWRRQALVYVKINFPAPMSHYMTGLLFGELDSDFDQMSDLYSSLGIIHLF
ALSGMQVGFFIDKFRWILLRLGLTKETVDKLQIPFSLVYAGLTGFSVSVVRSLVQKILGNLGLRKLDNFAVTVFICLLIL
PRFLLTAGGVLTFTYAFLLTVFDFEDLGQVKKAAVESLSISLGILPVLMTYFYAFQPLSILLTFVFSFVFDVLLLPGLSV
IFLLSPVVKMTWVNGFFIFMEKIIVWVADLGLRPWILGKPSELVLLLLLVSLFLLYDFHRRKKWLLGLSLVLALLFFITK
HPLENEVTVLDIGQGDSIFLRDMRGRTVLIDVGGRVDFAAKEAWQERSRQANAERTLIPYLHSRGVDRIDSLVLTHTEV

Nucleotide

• Length: 1680 bp

>NTDB_id=919753 VF946_RS05670 WP_395424540.1 1076013..1077692(-) (comEC/celB) [Streptococcus suis strain HB18]
ATGTCACGGTTGAGTAAGCTCCCCTGCCAGCCCGTTCACCTGGCAGTCTTGGCGGTGGCAGCTTACTTTGCAGTCCACTC
TTTTTCCCTCTTGACAATGTGCCTGCTCAGCTTGGTGTTAGCTGTCTTTGGTGTTCGGCAAGGTAAGACAGTTTTCCTCA
AAACGCTGCCGCTTCTAACCCTGTGTGGTCTCTTTTTCGGATGCCAAAAGGTCCAATGGGAGCGGGCAGCTCAGTCAGCC
CCAGAGCAAGTGACGACTGTGCAGGTCATTCCAGATACCATAGACATCAATGGCGACAGCTTGTCTTTTCGTGGTCGGGC
TGATGGACAAAACTATCAGGTTTTCTACAAATTAACCAGTCAGGAGGAGCAGACCTATTTTCAAAATCTGGCAGACCTGG
TCCAGCTAGAAGTGGAAGCAGAGGTCAGCCTGCCAGCTGGTCAGCGGAATTTCAAGGGCTTTGACTATCAGGCCTATCTG
AAAACACAGGGCATCTATCGGACTGTCAAGCTAACGGCGATTAAGAAGATTGTCCCTGTCCAGTCTTGGAATGTTTTTGA
CTGGCTGTCAACTTGGCGGAGGCAGGCCTTGGTCTATGTCAAAATCAATTTTCCGGCTCCCATGAGTCACTACATGACAG
GGCTTTTGTTTGGGGAGCTGGATAGTGATTTTGACCAGATGAGTGACCTCTATTCCAGTCTAGGAATCATTCATCTCTTT
GCCCTGTCTGGTATGCAGGTGGGCTTTTTCATCGACAAGTTTCGTTGGATTTTGTTGCGTCTGGGCTTGACCAAGGAAAC
AGTGGATAAGTTACAAATTCCCTTTTCCCTTGTCTATGCTGGTTTGACAGGCTTTTCTGTGTCGGTGGTGCGGTCCTTGG
TCCAAAAAATTCTGGGTAATCTAGGCTTGCGGAAGTTGGATAATTTTGCGGTGACGGTCTTTATCTGTCTGTTGATACTG
CCCCGATTTTTACTGACAGCAGGAGGAGTGCTGACTTTTACTTATGCTTTCTTGCTGACGGTCTTTGATTTTGAGGATTT
GGGGCAGGTCAAAAAGGCTGCGGTGGAGAGCCTCAGTATTTCACTGGGAATTTTGCCGGTGCTTATGACCTATTTCTATG
CCTTTCAGCCTCTATCTATCCTCTTGACCTTTGTCTTTTCCTTTGTCTTTGATGTCCTACTCTTGCCAGGTTTGTCAGTC
ATTTTTCTCCTGTCGCCAGTTGTCAAGATGACTTGGGTCAACGGATTTTTCATCTTTATGGAGAAAATCATTGTCTGGGT
GGCTGATTTGGGATTGCGGCCTTGGATACTGGGCAAGCCGTCTGAGCTGGTCCTCTTGCTTTTGCTGGTCAGCCTCTTCT
TGCTCTACGATTTCCACAGGAGAAAGAAATGGCTTCTAGGACTGAGCTTGGTCCTCGCTCTGCTATTTTTCATCACCAAA
CACCCGCTGGAAAATGAGGTGACGGTGCTGGACATCGGGCAGGGGGACAGCATCTTTTTGCGGGATATGCGGGGGCGGAC
GGTTCTGATTGATGTAGGCGGACGAGTCGATTTCGCGGCCAAGGAAGCGTGGCAGGAGCGGTCTCGGCAGGCAAATGCAG
AGCGGACTTTGATTCCCTATCTGCATAGTCGGGGTGTGGATAGGATTGATAGTTTAGTCCTGACCCACACCGAAGTGTGA

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (30-175)

• Competence protein (Competence) (215-461)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	52.432	99.284	0.521
comEC/celB	Streptococcus mitis NCTC 12261	51.724	98.569	0.51
comEC/celB	Streptococcus pneumoniae TIGR4	51.277	98.032	0.503
comEC/celB	Streptococcus pneumoniae Rx1	51.095	98.032	0.501
comEC/celB	Streptococcus pneumoniae D39	51.095	98.032	0.501
comEC/celB	Streptococcus pneumoniae R6	51.095	98.032	0.501
comEC	Lactococcus lactis subsp. cremoris KW2	46.809	100	0.472