Detailed information
Bioinformatically predicted
Overview
| Name | comGA | Type | Machinery gene |
| Locus tag | VDS61_RS05005 | Genome accession | NZ_CP141812 |
| Coordinates | 963880..964755 (+) | Length | 291 a.a. |
| NCBI ID | WP_126133420.1 | Uniprot ID | - |
| Organism | Latilactobacillus curvatus strain K285 | ||
| Function | dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 964722..1003982 | 963880..964755 | flank | -33 |
Gene organization within MGE regions
Location: 963880..1003982
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| VDS61_RS05005 (VDS61_04990) | comGA | 963880..964755 (+) | 876 | WP_126133420.1 | competence type IV pilus ATPase ComGA | Machinery gene |
| VDS61_RS05010 (VDS61_04995) | comGB | 964745..965746 (+) | 1002 | WP_076786758.1 | type II secretion system F family protein | Machinery gene |
| VDS61_RS05015 (VDS61_05000) | - | 965799..967223 (-) | 1425 | WP_324722217.1 | recombinase family protein | - |
| VDS61_RS05020 (VDS61_05005) | - | 967336..968217 (-) | 882 | WP_324722218.1 | Ltp family lipoprotein | - |
| VDS61_RS05025 (VDS61_05010) | - | 968280..968996 (-) | 717 | WP_065825488.1 | hypothetical protein | - |
| VDS61_RS05030 (VDS61_05015) | - | 969017..969409 (-) | 393 | WP_324722219.1 | DUF4064 domain-containing protein | - |
| VDS61_RS05035 (VDS61_05020) | - | 969530..970246 (-) | 717 | WP_065825488.1 | hypothetical protein | - |
| VDS61_RS05040 (VDS61_05025) | - | 970267..970659 (-) | 393 | WP_324722219.1 | DUF4064 domain-containing protein | - |
| VDS61_RS05045 (VDS61_05030) | - | 970780..971496 (-) | 717 | WP_065825488.1 | hypothetical protein | - |
| VDS61_RS05050 (VDS61_05035) | - | 971517..971909 (-) | 393 | WP_324722219.1 | DUF4064 domain-containing protein | - |
| VDS61_RS05055 (VDS61_05040) | - | 971981..972382 (-) | 402 | WP_284182909.1 | ImmA/IrrE family metallo-endopeptidase | - |
| VDS61_RS05060 (VDS61_05045) | - | 972384..972719 (-) | 336 | WP_259770237.1 | helix-turn-helix domain-containing protein | - |
| VDS61_RS05065 (VDS61_05050) | - | 972868..973095 (+) | 228 | WP_284182910.1 | helix-turn-helix domain-containing protein | - |
| VDS61_RS05070 (VDS61_05055) | - | 973114..973278 (+) | 165 | WP_155759442.1 | hypothetical protein | - |
| VDS61_RS05075 (VDS61_05060) | - | 973338..973889 (+) | 552 | WP_324722220.1 | helix-turn-helix transcriptional regulator | - |
| VDS61_RS05080 (VDS61_05065) | - | 973886..974038 (+) | 153 | WP_324722221.1 | BOW99_gp33 family protein | - |
| VDS61_RS05085 (VDS61_05070) | - | 974345..974527 (+) | 183 | WP_324722222.1 | hypothetical protein | - |
| VDS61_RS05090 (VDS61_05075) | - | 974527..974997 (+) | 471 | WP_324722223.1 | host-nuclease inhibitor Gam family protein | - |
| VDS61_RS05095 (VDS61_05080) | - | 975009..975722 (+) | 714 | WP_284182969.1 | AAA family ATPase | - |
| VDS61_RS05100 (VDS61_05085) | - | 975715..976293 (+) | 579 | WP_324722224.1 | DUF669 domain-containing protein | - |
| VDS61_RS05105 (VDS61_05090) | - | 976306..977265 (+) | 960 | WP_324722225.1 | DnaD domain protein | - |
| VDS61_RS05110 (VDS61_05095) | - | 977465..977995 (+) | 531 | WP_324722226.1 | helix-turn-helix domain-containing protein | - |
| VDS61_RS05115 (VDS61_05100) | - | 977964..978173 (+) | 210 | WP_155760084.1 | DUF6877 family protein | - |
| VDS61_RS05120 (VDS61_05105) | - | 978173..978337 (+) | 165 | WP_155275678.1 | hypothetical protein | - |
| VDS61_RS05125 (VDS61_05110) | - | 978352..978546 (+) | 195 | WP_039098503.1 | hypothetical protein | - |
| VDS61_RS05130 (VDS61_05115) | - | 978621..979613 (+) | 993 | WP_324722227.1 | DNA cytosine methyltransferase | - |
| VDS61_RS05135 (VDS61_05120) | - | 979870..980271 (+) | 402 | WP_324722228.1 | YopX family protein | - |
| VDS61_RS05140 (VDS61_05125) | - | 980271..980399 (+) | 129 | WP_324722229.1 | hypothetical protein | - |
| VDS61_RS05145 (VDS61_05130) | - | 980399..980863 (+) | 465 | WP_324722230.1 | DUF1064 domain-containing protein | - |
| VDS61_RS05150 (VDS61_05135) | - | 980875..981078 (+) | 204 | WP_065825503.1 | hypothetical protein | - |
| VDS61_RS05155 (VDS61_05140) | - | 981098..981280 (+) | 183 | WP_065825504.1 | hypothetical protein | - |
| VDS61_RS05160 (VDS61_05145) | - | 981280..981516 (+) | 237 | WP_039098607.1 | helix-turn-helix domain-containing protein | - |
| VDS61_RS05165 (VDS61_05150) | - | 981630..982055 (+) | 426 | WP_065825505.1 | ArpU family phage packaging/lysis transcriptional regulator | - |
| VDS61_RS05170 (VDS61_05155) | - | 982653..983021 (-) | 369 | WP_324722231.1 | hypothetical protein | - |
| VDS61_RS05175 (VDS61_05160) | - | 983074..983241 (+) | 168 | WP_324722232.1 | hypothetical protein | - |
| VDS61_RS05180 (VDS61_05165) | - | 983297..983455 (+) | 159 | WP_186738740.1 | hypothetical protein | - |
| VDS61_RS05185 (VDS61_05170) | - | 983461..983634 (+) | 174 | WP_157779297.1 | hypothetical protein | - |
| VDS61_RS05190 (VDS61_05175) | - | 983634..984488 (+) | 855 | WP_324722233.1 | terminase small subunit | - |
| VDS61_RS05195 (VDS61_05180) | - | 984472..985755 (+) | 1284 | WP_324722258.1 | PBSX family phage terminase large subunit | - |
| VDS61_RS05200 (VDS61_05185) | - | 985766..987214 (+) | 1449 | WP_324722234.1 | phage portal protein | - |
| VDS61_RS05205 (VDS61_05190) | - | 987156..987470 (+) | 315 | WP_069468053.1 | ribosomal-processing cysteine protease Prp | - |
| VDS61_RS05210 (VDS61_05195) | - | 987473..988666 (+) | 1194 | WP_324722235.1 | minor capsid protein | - |
| VDS61_RS05215 (VDS61_05200) | - | 988835..989482 (+) | 648 | WP_324722236.1 | DUF4355 domain-containing protein | - |
| VDS61_RS05220 (VDS61_05205) | - | 989495..989851 (+) | 357 | WP_273960332.1 | hypothetical protein | - |
| VDS61_RS05225 (VDS61_05210) | - | 989874..990935 (+) | 1062 | WP_324722237.1 | major capsid protein | - |
| VDS61_RS05230 (VDS61_05215) | - | 990950..991270 (+) | 321 | WP_324722238.1 | phage head-tail connector protein | - |
| VDS61_RS05235 (VDS61_05220) | - | 991267..991653 (+) | 387 | WP_283534150.1 | hypothetical protein | - |
| VDS61_RS05240 (VDS61_05225) | - | 991628..992149 (+) | 522 | WP_411377918.1 | HK97 gp10 family phage protein | - |
| VDS61_RS05245 (VDS61_05230) | - | 992151..992516 (+) | 366 | WP_039098634.1 | hypothetical protein | - |
| VDS61_RS05250 (VDS61_05235) | - | 992529..992993 (+) | 465 | WP_065825517.1 | phage tail tube protein | - |
| VDS61_RS05255 (VDS61_05240) | - | 993050..993241 (+) | 192 | Protein_1002 | Ig domain-containing protein | - |
| VDS61_RS05260 (VDS61_05245) | - | 993265..993669 (+) | 405 | WP_039098623.1 | DUF6096 family protein | - |
| VDS61_RS05265 (VDS61_05250) | - | 993690..994067 (+) | 378 | WP_324722239.1 | hypothetical protein | - |
| VDS61_RS05270 (VDS61_05255) | - | 994064..994264 (+) | 201 | WP_324722240.1 | hypothetical protein | - |
| VDS61_RS05275 (VDS61_05260) | - | 994250..994624 (-) | 375 | WP_182159654.1 | DUF2513 domain-containing protein | - |
| VDS61_RS05280 (VDS61_05265) | - | 994682..999487 (+) | 4806 | WP_324722241.1 | phage tail protein | - |
| VDS61_RS05285 (VDS61_05270) | - | 999503..999862 (+) | 360 | WP_324722242.1 | DUF6711 family protein | - |
Sequence
Protein
Download Length: 291 a.a. Molecular weight: 32061.88 Da Isoelectric Point: 5.3292
>NTDB_id=919669 VDS61_RS05005 WP_126133420.1 963880..964755(+) (comGA) [Latilactobacillus curvatus strain K285]
MTEVLTTLLQKCATEKAQDLYFRPLSTGWAIIERLATGLKPLQKVTLSEGNQWLNQMKYQAGMDISETRRPQTGRSAIEV
AGELIYLRLATVGDFLNRESLVVRFIYPIGQTYHCDDSQILSRLMQLIQQPGLLLFAGPTGSGKTTSLYYLAEQIMQDKM
VVAIEDPIEIQQPAFLQLQVNEAAGLTYAALLKISLRLRPDTLIIGEIRDLQTAQHAVSAALSGHLVLSTIHARSTTGVM
DRLLDLGISHSQLTACLAGVAYQSLVVEGQNVAAHYELATAQQLEEAVHED
MTEVLTTLLQKCATEKAQDLYFRPLSTGWAIIERLATGLKPLQKVTLSEGNQWLNQMKYQAGMDISETRRPQTGRSAIEV
AGELIYLRLATVGDFLNRESLVVRFIYPIGQTYHCDDSQILSRLMQLIQQPGLLLFAGPTGSGKTTSLYYLAEQIMQDKM
VVAIEDPIEIQQPAFLQLQVNEAAGLTYAALLKISLRLRPDTLIIGEIRDLQTAQHAVSAALSGHLVLSTIHARSTTGVM
DRLLDLGISHSQLTACLAGVAYQSLVVEGQNVAAHYELATAQQLEEAVHED
Nucleotide
Download Length: 876 bp
>NTDB_id=919669 VDS61_RS05005 WP_126133420.1 963880..964755(+) (comGA) [Latilactobacillus curvatus strain K285]
ATGACCGAAGTATTAACAACCCTTTTGCAAAAGTGCGCAACGGAAAAAGCGCAGGATCTTTATTTTCGACCACTATCGAC
GGGTTGGGCAATTATTGAACGCTTAGCGACAGGACTAAAGCCGTTACAAAAAGTTACTCTGTCAGAAGGCAATCAATGGC
TCAATCAAATGAAGTATCAAGCGGGGATGGATATCAGTGAAACTCGGCGTCCACAGACCGGCCGTTCAGCGATCGAGGTG
GCAGGCGAATTGATTTATTTACGGTTGGCAACCGTGGGGGATTTTTTGAATCGGGAAAGTTTAGTTGTTCGTTTCATTTA
TCCCATTGGGCAGACTTATCATTGCGACGACTCGCAGATTTTAAGTCGTTTAATGCAGTTAATTCAGCAACCAGGATTAT
TGCTATTTGCCGGTCCAACTGGTTCAGGGAAGACAACAAGTTTGTACTATCTTGCGGAACAAATCATGCAAGATAAAATG
GTGGTTGCGATTGAAGATCCGATAGAGATTCAACAGCCAGCGTTCTTACAGTTACAGGTGAATGAAGCCGCAGGGTTAAC
CTATGCAGCATTGTTGAAAATCAGTCTGCGATTACGGCCTGATACCTTAATTATTGGTGAGATTCGCGACTTACAGACGG
CCCAACACGCGGTTTCAGCGGCGTTGAGCGGTCACTTGGTACTAAGTACGATTCACGCGCGAAGTACAACGGGGGTGATG
GACCGTCTATTAGATCTTGGAATTAGCCACTCACAATTAACCGCTTGTTTAGCGGGTGTTGCCTATCAATCACTAGTGGT
CGAAGGCCAAAATGTAGCGGCCCACTATGAGTTAGCAACTGCACAACAATTGGAGGAGGCTGTTCATGAAGACTAA
ATGACCGAAGTATTAACAACCCTTTTGCAAAAGTGCGCAACGGAAAAAGCGCAGGATCTTTATTTTCGACCACTATCGAC
GGGTTGGGCAATTATTGAACGCTTAGCGACAGGACTAAAGCCGTTACAAAAAGTTACTCTGTCAGAAGGCAATCAATGGC
TCAATCAAATGAAGTATCAAGCGGGGATGGATATCAGTGAAACTCGGCGTCCACAGACCGGCCGTTCAGCGATCGAGGTG
GCAGGCGAATTGATTTATTTACGGTTGGCAACCGTGGGGGATTTTTTGAATCGGGAAAGTTTAGTTGTTCGTTTCATTTA
TCCCATTGGGCAGACTTATCATTGCGACGACTCGCAGATTTTAAGTCGTTTAATGCAGTTAATTCAGCAACCAGGATTAT
TGCTATTTGCCGGTCCAACTGGTTCAGGGAAGACAACAAGTTTGTACTATCTTGCGGAACAAATCATGCAAGATAAAATG
GTGGTTGCGATTGAAGATCCGATAGAGATTCAACAGCCAGCGTTCTTACAGTTACAGGTGAATGAAGCCGCAGGGTTAAC
CTATGCAGCATTGTTGAAAATCAGTCTGCGATTACGGCCTGATACCTTAATTATTGGTGAGATTCGCGACTTACAGACGG
CCCAACACGCGGTTTCAGCGGCGTTGAGCGGTCACTTGGTACTAAGTACGATTCACGCGCGAAGTACAACGGGGGTGATG
GACCGTCTATTAGATCTTGGAATTAGCCACTCACAATTAACCGCTTGTTTAGCGGGTGTTGCCTATCAATCACTAGTGGT
CGAAGGCCAAAATGTAGCGGCCCACTATGAGTTAGCAACTGCACAACAATTGGAGGAGGCTGTTCATGAAGACTAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comGA | Latilactobacillus sakei subsp. sakei 23K |
69.892 |
95.876 |
0.67 |
| comGA/cglA/cilD | Streptococcus mitis NCTC 12261 |
43.015 |
93.471 |
0.402 |
| comGA/cglA | Streptococcus sobrinus strain NIDR 6715-7 |
42.593 |
92.784 |
0.395 |
| comGA/cglA/cilD | Streptococcus pneumoniae TIGR4 |
41.573 |
91.753 |
0.381 |
| comGA/cglA/cilD | Streptococcus pneumoniae R6 |
41.573 |
91.753 |
0.381 |
| comGA/cglA/cilD | Streptococcus pneumoniae Rx1 |
41.573 |
91.753 |
0.381 |
| comGA/cglA/cilD | Streptococcus pneumoniae D39 |
41.573 |
91.753 |
0.381 |
| comGA | Lactococcus lactis subsp. cremoris KW2 |
41.603 |
90.034 |
0.375 |
| comYA | Streptococcus mutans UA140 |
37.113 |
100 |
0.371 |
| comYA | Streptococcus mutans UA159 |
37.113 |
100 |
0.371 |
| comYA | Streptococcus gordonii str. Challis substr. CH1 |
39.194 |
93.814 |
0.368 |