Detailed information NTG0918074

Bioinformatically predicted

Overview

• Name: comGC
• Type: Machinery gene
• Locus tag: AB1F71_RS09185
• Genome accession: NZ_CP160386
• Coordinates: 1853024..1853338 (-)
• Length: 104 a.a.
• NCBI ID: WP_002263437.1
• Uniprot ID: Q8DS51
• Organism: Streptococcus mutans strain UA159 ykuR deletion
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1848024..1858338

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AB1F71_RS09145 (AB1F71_09145)	-	1848091..1848531 (-)	441	WP_002263445.1	hypothetical protein	-
AB1F71_RS09150 (AB1F71_09150)	-	1848500..1848745 (-)	246	WP_002263444.1	helix-turn-helix transcriptional regulator	-
AB1F71_RS09155 (AB1F71_09155)	-	1849314..1850513 (-)	1200	WP_002263443.1	acetate kinase	-
AB1F71_RS09160 (AB1F71_09160)	comGH	1850572..1851525 (-)	954	WP_002263442.1	class I SAM-dependent methyltransferase	Machinery gene
AB1F71_RS09165 (AB1F71_09165)	comGG	1851580..1851969 (-)	390	WP_002263441.1	competence type IV pilus minor pilin ComGG	Machinery gene
AB1F71_RS09170 (AB1F71_09170)	comGF	1851947..1852381 (-)	435	WP_002263440.1	competence type IV pilus minor pilin ComGF	Machinery gene
AB1F71_RS09175 (AB1F71_09175)	comGE	1852368..1852661 (-)	294	WP_002263439.1	competence type IV pilus minor pilin ComGE	Machinery gene
AB1F71_RS09180 (AB1F71_09180)	comGD	1852633..1853037 (-)	405	WP_002263438.1	competence type IV pilus minor pilin ComGD	Machinery gene
AB1F71_RS09185 (AB1F71_09185)	comGC	1853024..1853338 (-)	315	WP_002263437.1	competence type IV pilus major pilin ComGC	Machinery gene
AB1F71_RS09190 (AB1F71_09190)	comGB	1853338..1854369 (-)	1032	WP_255262721.1	competence type IV pilus assembly protein ComGB	Machinery gene
AB1F71_RS09195 (AB1F71_09195)	comGA	1854305..1855246 (-)	942	WP_002263435.1	competence type IV pilus ATPase ComGA	Machinery gene
AB1F71_RS09200 (AB1F71_09200)	-	1855376..1855759 (-)	384	WP_002263434.1	DUF1033 family protein	-

Sequence

Protein

• Length: 104 a.a.
• Molecular weight: 11591.60 Da
• Isoelectric Point: 10.2206

>NTDB_id=918074 AB1F71_RS09185 WP_002263437.1 1853024..1853338(-) (comGC) [Streptococcus mutans strain UA159 ykuR deletion]
MKKIKRVSVRAFTLIEMLVVLLIISILLLLFVPNLTKQKDKVKDTGGSAVVKVVESQAELYELNKTDSATLSKLVASGDI
TQEQANSYKDYYAKHPSKTRHVAN

Nucleotide

• Length: 315 bp

>NTDB_id=918074 AB1F71_RS09185 WP_002263437.1 1853024..1853338(-) (comGC) [Streptococcus mutans strain UA159 ykuR deletion]
ATGAAAAAGATCAAGAGAGTCAGTGTACGGGCTTTTACGCTTATAGAAATGTTAGTAGTTCTTCTCATTATTAGTATTCT
TTTACTATTATTTGTTCCTAATTTAACTAAGCAAAAAGATAAGGTAAAAGATACTGGCGGTTCTGCCGTGGTTAAAGTTG
TAGAAAGTCAGGCTGAGCTTTATGAGCTTAATAAAACCGATTCTGCTACTCTTTCTAAATTAGTAGCTAGTGGTGATATT
ACACAAGAACAGGCAAATTCATACAAGGATTACTATGCAAAACACCCAAGTAAAACACGGCATGTCGCGAATTAA

Domains

Predicted by InterProScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (9-30)

3D structure

• AlphaFold DB: Q8DS51

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGC	Streptococcus mutans UA140	100	100	1
comGC	Streptococcus mutans UA159	100	100	1
comGC	Streptococcus gordonii str. Challis substr. CH1	71.429	100	0.721
comGC/cglC	Streptococcus mitis SK321	66.667	95.192	0.635
comGC/cglC	Streptococcus mitis NCTC 12261	69.565	88.462	0.615
comGC/cglC	Streptococcus pneumoniae R6	63.636	95.192	0.606
comGC/cglC	Streptococcus pneumoniae Rx1	63.636	95.192	0.606
comGC/cglC	Streptococcus pneumoniae D39	63.636	95.192	0.606
comGC/cglC	Streptococcus pneumoniae TIGR4	63.636	95.192	0.606
comGC	Lactococcus lactis subsp. cremoris KW2	55.446	97.115	0.538
comGC	Streptococcus suis isolate S10	60.227	84.615	0.51