Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   L6411_RS00415 Genome accession   NZ_AP025333
Coordinates   67621..68802 (+) Length   393 a.a.
NCBI ID   WP_237374194.1    Uniprot ID   -
Organism   Streptococcus ruminantium strain GUT-189     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 62621..73802
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L6411_RS00395 (GUT189_00590) - 62765..64264 (+) 1500 WP_155962533.1 quinol oxidase -
  L6411_RS00400 (GUT189_00600) mutL 64402..66339 (+) 1938 WP_237374191.1 DNA mismatch repair endonuclease MutL -
  L6411_RS00405 (GUT189_00610) ruvA 66368..66958 (+) 591 WP_155969326.1 Holliday junction branch migration protein RuvA -
  L6411_RS00410 (GUT189_00620) - 67008..67562 (+) 555 WP_024532323.1 DNA-3-methyladenine glycosylase I -
  L6411_RS00415 (GUT189_00630) cinA 67621..68802 (+) 1182 WP_237374194.1 competence/damage-inducible protein A Machinery gene
  L6411_RS00420 (GUT189_00640) recA 68854..69996 (+) 1143 WP_024532325.1 recombinase RecA Machinery gene
  L6411_RS00425 (GUT189_00650) spx 70525..70923 (+) 399 WP_024532326.1 transcriptional regulator Spx -
  L6411_RS00430 (GUT189_00660) - 71027..71293 (+) 267 WP_002939360.1 IreB family regulatory phosphoprotein -
  L6411_RS00435 (GUT189_00670) ruvX 71293..71712 (+) 420 WP_032537883.1 Holliday junction resolvase RuvX -
  L6411_RS00440 (GUT189_00680) - 71724..72029 (+) 306 WP_024532328.1 DUF1292 domain-containing protein -
  L6411_RS00445 (GUT189_00690) - 72304..72849 (+) 546 WP_237374195.1 nucleotidyltransferase family protein -
  L6411_RS00450 (GUT189_00700) comX/sigX 72942..73412 (+) 471 WP_024532329.1 sigma-70 family RNA polymerase sigma factor Regulator

Sequence

Protein


Download         Length: 393 a.a.        Molecular weight: 42522.60 Da        Isoelectric Point: 4.7409

>NTDB_id=91213 L6411_RS00415 WP_237374194.1 67621..68802(+) (cinA) [Streptococcus ruminantium strain GUT-189]
MKAELIAVGTEILTGQIVNTNTQFLSEKCAELGIDVYFHTSVGDNQGRLLQVLDIASRRSDLVILCGGLGPTEDDLTKQT
LARFLGKELVLDEQAKLKLDRFFASRPGRIRTPNNERQAQIVAGSTPLQNPAGLAVGGLIEQEGITYVVLPGPPSELKAM
FTTSLLPMLDNSHSQLYSRVMRFFGIGESQLVTILADLIDNQTNPTLAPYAKVGEVTLRLSTKATCQEEADQVLDRLETQ
ILQRDKLAEYFYAYGEENSLVKLVATSLAGKEQTLAVWEQGTGGLLQAELSLALAEQPYFIGGRVVGQKGAASGNLSVQA
SGIRDDLQADLGLAMSVFIKPSSTVDNVLAKVSLALSSPSGVIQKELDLGGYSWQHIRQLACLQALDFVRNTL

Nucleotide


Download         Length: 1182 bp        

>NTDB_id=91213 L6411_RS00415 WP_237374194.1 67621..68802(+) (cinA) [Streptococcus ruminantium strain GUT-189]
ATGAAAGCAGAACTAATCGCTGTTGGAACGGAGATTTTAACAGGGCAGATTGTTAATACGAATACTCAGTTTCTATCCGA
AAAATGTGCAGAGCTGGGAATTGATGTCTACTTCCACACAAGTGTTGGAGACAACCAAGGTAGACTTTTACAGGTGCTGG
ATATAGCCAGTAGACGCAGTGATTTGGTCATTCTATGTGGAGGTCTTGGCCCTACGGAAGATGATTTAACCAAACAAACA
TTAGCTCGATTTTTAGGGAAAGAATTAGTTTTGGATGAGCAGGCCAAGCTTAAATTAGACCGTTTTTTTGCTAGTCGTCC
AGGTCGTATTCGCACACCTAACAATGAACGTCAGGCACAGATTGTAGCAGGAAGTACCCCCTTGCAAAATCCTGCTGGTT
TAGCCGTTGGGGGATTGATTGAGCAAGAAGGAATAACCTATGTTGTACTTCCAGGCCCTCCGAGTGAGCTAAAAGCTATG
TTTACTACCAGTCTATTGCCGATGCTAGACAATTCTCATAGCCAACTTTACTCACGGGTTATGAGATTTTTTGGTATTGG
AGAAAGTCAGCTGGTGACGATTTTAGCAGATTTGATTGATAATCAGACTAATCCAACTTTAGCACCTTATGCTAAAGTCG
GTGAAGTCACCTTGCGCCTGTCTACCAAAGCTACTTGCCAAGAAGAAGCAGATCAAGTATTGGATCGTTTAGAAACACAA
ATTTTGCAACGTGATAAACTAGCAGAGTATTTCTATGCCTATGGTGAGGAAAATAGTCTGGTGAAATTGGTGGCGACCAG
CTTGGCGGGGAAAGAGCAAACTCTGGCTGTATGGGAACAGGGGACGGGTGGGCTCTTACAAGCAGAATTGAGTTTGGCGC
TGGCCGAACAGCCTTATTTTATCGGAGGTAGGGTTGTTGGTCAGAAAGGAGCTGCTTCGGGCAATTTGTCTGTTCAAGCA
AGCGGTATTCGTGACGATCTACAAGCCGATTTAGGTTTAGCTATGTCGGTTTTTATCAAGCCGTCCTCAACGGTAGACAA
CGTTCTTGCTAAGGTCTCACTGGCCTTATCAAGTCCTTCTGGAGTTATTCAAAAGGAGCTAGATTTGGGAGGTTATTCAT
GGCAACATATCCGTCAACTAGCTTGTTTACAAGCTCTAGATTTTGTACGAAATACTTTGTGA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-253)

Competence-damaged protein (CinA)

(309-393)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus suis isolate S10

78.626

100

0.786
  cinA Streptococcus mitis SK321

55.288

100

0.585
  cinA Streptococcus mitis NCTC 12261

54.808

100

0.58
  cinA Streptococcus mutans UA159

54.988

100

0.575
  cinA Streptococcus pneumoniae TIGR4

54.327

100

0.575
  cinA Streptococcus pneumoniae Rx1

54.327

100

0.575
  cinA Streptococcus pneumoniae R6

54.327

100

0.575
  cinA Streptococcus pneumoniae D39

54.087

100

0.573
  cinA Bacillus subtilis subsp. subtilis str. 168

47.883

78.117

0.374

Multiple sequence alignment