Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   L6419_RS00420 Genome accession   NZ_AP025332
Coordinates   70135..71316 (+) Length   393 a.a.
NCBI ID   WP_237375479.1    Uniprot ID   -
Organism   Streptococcus ruminantium strain GUT-184     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 65135..76316
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L6419_RS00400 (GUT184_00600) - 65279..66778 (+) 1500 WP_155969328.1 quinol oxidase -
  L6419_RS00405 (GUT184_00610) mutL 66916..68853 (+) 1938 WP_237375476.1 DNA mismatch repair endonuclease MutL -
  L6419_RS00410 (GUT184_00620) ruvA 68882..69472 (+) 591 WP_155969326.1 Holliday junction branch migration protein RuvA -
  L6419_RS00415 (GUT184_00630) - 69522..70076 (+) 555 WP_237375478.1 DNA-3-methyladenine glycosylase I -
  L6419_RS00420 (GUT184_00640) cinA 70135..71316 (+) 1182 WP_237375479.1 competence/damage-inducible protein A Machinery gene
  L6419_RS00425 (GUT184_00650) recA 71368..72510 (+) 1143 WP_024532325.1 recombinase RecA Machinery gene
  L6419_RS00430 (GUT184_00660) spx 73041..73439 (+) 399 WP_024532326.1 transcriptional regulator Spx -
  L6419_RS00435 (GUT184_00670) - 73543..73809 (+) 267 WP_002939360.1 IreB family regulatory phosphoprotein -
  L6419_RS00440 (GUT184_00680) ruvX 73809..74228 (+) 420 WP_032537883.1 Holliday junction resolvase RuvX -
  L6419_RS00445 (GUT184_00690) - 74240..74545 (+) 306 WP_024532328.1 DUF1292 domain-containing protein -
  L6419_RS00450 - 74820..75366 (+) 547 Protein_70 nucleotidyltransferase family protein -
  L6419_RS00455 (GUT184_00720) comX/sigX 75459..75929 (+) 471 WP_155973900.1 sigma-70 family RNA polymerase sigma factor Regulator

Sequence

Protein


Download         Length: 393 a.a.        Molecular weight: 42486.51 Da        Isoelectric Point: 4.8959

>NTDB_id=91160 L6419_RS00420 WP_237375479.1 70135..71316(+) (cinA) [Streptococcus ruminantium strain GUT-184]
MKAELIAVGTEILTGQIVNTNTQFLSEKCAELGIDVYFHTSVGDNQGRLLQVLDIASRRSDLVILCGGLGPTEDDLTKQT
LARFLGKELVLDEQAKLKLDRFFASRPGRIRTPNNERQAQIVAGSTPLQNPAGLAVGGLIEQEGITYVVLPGPPSELKAM
FTTSLLPMLGNSHSQLYSRVLRFFGIGESQLVTILADLIDNQTNPTLAPYAKVGEVTLRLSTKATCQEEADQVLDRLETQ
ILQRDKLAEYFYAYGEENSLVKLVATSLAGKEQTLAVWEQGTGGHLQAELSLALAEQPYFIGGRVVGQKGAASGNLSVQA
SGIRDDLQADLGLAMSVFIKPSSTVDNVLSKVSLALSSPSGVIQKELDLGGYSWQHIRQLACLQALDFVRNTL

Nucleotide


Download         Length: 1182 bp        

>NTDB_id=91160 L6419_RS00420 WP_237375479.1 70135..71316(+) (cinA) [Streptococcus ruminantium strain GUT-184]
ATGAAAGCAGAACTAATCGCTGTTGGAACGGAGATTTTAACAGGGCAGATTGTTAATACGAATACTCAGTTTCTATCCGA
AAAATGTGCAGAGCTGGGAATTGATGTCTACTTCCACACAAGTGTTGGAGACAACCAAGGTAGACTTTTACAGGTGCTGG
ATATAGCCAGTAGACGCAGTGATTTGGTCATTCTATGTGGAGGTCTTGGCCCTACGGAAGATGATTTAACCAAACAAACA
TTAGCTCGATTTTTAGGGAAAGAATTAGTTTTGGATGAGCAGGCCAAGCTTAAATTAGACCGTTTTTTTGCTAGTCGTCC
AGGTCGTATTCGCACACCTAACAATGAACGTCAGGCACAGATTGTAGCAGGAAGTACCCCCTTGCAAAATCCTGCTGGTT
TAGCCGTTGGGGGATTGATTGAGCAAGAAGGAATAACCTATGTTGTACTTCCAGGCCCTCCGAGTGAGCTAAAAGCTATG
TTTACTACCAGTCTATTGCCGATGCTAGGCAATTCTCATAGCCAACTTTACTCACGGGTTCTGAGATTTTTTGGTATTGG
AGAAAGTCAGCTGGTGACGATTTTAGCAGATTTGATTGATAATCAGACTAATCCAACTTTAGCACCTTATGCTAAAGTCG
GTGAAGTCACCTTGCGCCTGTCTACCAAAGCTACTTGCCAAGAAGAAGCAGATCAAGTATTGGATCGTTTAGAAACACAA
ATTTTGCAACGTGATAAACTAGCAGAGTATTTCTATGCCTATGGCGAAGAAAATAGTCTGGTGAAATTGGTGGCAACCAG
CTTGGCGGGGAAAGAGCAAACTCTGGCTGTATGGGAACAGGGGACGGGTGGGCACTTACAAGCAGAATTGAGTTTGGCAC
TGGCCGAACAGCCTTATTTTATCGGAGGTAGGGTTGTTGGTCAGAAAGGAGCTGCTTCGGGCAATTTGTCTGTTCAAGCA
AGCGGTATTCGTGACGATCTACAAGCCGATTTAGGTTTAGCTATGTCGGTTTTTATCAAGCCGTCCTCAACGGTAGACAA
CGTTCTTTCCAAGGTCTCACTGGCCTTATCAAGTCCTTCTGGAGTTATTCAAAAGGAGCTAGATTTGGGAGGTTATTCAT
GGCAACATATCCGTCAACTAGCTTGTTTACAAGCTCTAGATTTTGTACGAAATACTTTGTGA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(309-393)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-253)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus suis isolate S10

78.372

100

0.784
  cinA Streptococcus mitis SK321

55.288

100

0.585
  cinA Streptococcus mitis NCTC 12261

54.808

100

0.58
  cinA Streptococcus mutans UA159

54.988

100

0.575
  cinA Streptococcus pneumoniae TIGR4

54.327

100

0.575
  cinA Streptococcus pneumoniae Rx1

54.327

100

0.575
  cinA Streptococcus pneumoniae R6

54.327

100

0.575
  cinA Streptococcus pneumoniae D39

54.087

100

0.573
  cinA Bacillus subtilis subsp. subtilis str. 168

47.883

78.117

0.374

Multiple sequence alignment